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10 results for “Immune Complexes”
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Research ArticleOpen accessPhrase in the titleExploring the Role of Immune Complexes in Essential HypertensionIvan MilosevicEssential hypertension is a rise of arterial blood pressure whose etiology is unknown. Immune complexes are complexes created by the binding of an antibody to the antigen. They are also called circulating immune complexes because of its precipitation in peripheral blood vessels, commonly on the places of their bifurcation and the places of higher blood pressure (glomerules of kidney or … …American Journal of Immunology, Vol. 18, Issue 1 · 2 Nov 2022 · 9,974 accessesView PDFCite
Review ArticleOpen accessPhrase in the titleCirculating Immune Complexes as an Important Link between Inflammation and Lipid Alterations in AtherosclerosisAnastasia Vladimirovna Poznyak, Nikolay Alexandrovich Orekhov, Vasily Nikolaevich Sukhorukov et al.This review article rigorously investigates the emerging facets of atherosclerosis pathogenesis through an exhaustive examination of the existing data on the intricate interplay between lipid metabolism disorders and inflammation. A primary objective of this study is to thoroughly explore the role of Circulating Immune Complexes (CIC) as a pivotal indicator of this multifaceted interaction. The focus of this review centers … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 14 Aug 2024 · 3,926 accessesView PDFCite
Case ReportOpen accessIn the abstractConsumption of an Extremely Biodiverse Probiotic and a Supplement based on Microbial Chondroitin Sulfate is Associated with Very Low Serum Alpha-N-acetylgalactosaminidase (Nagalase) Activity and Decrease of C-reactive Protein ValuesMichael Carter, Stefania Pacini, Marco RuggieroWe describe the case of a 57-years-old male healthy professional who added to his nutritional plan a novel, extremely biodiverse, probiotic and a supplement based on microbial chondroitin sulfate, vitamin D3 and ultrapure phosphatidylcholine to improve his healthy life expectancy. After three months of such a nutritional regimen, serum alpha-N-acetylgalactosaminidase (nagalase) activity was 0.40 that is a value below the … …American Journal of Immunology, Vol. 16, Issue 1 · 22 Apr 2020 · 13,049 accessesView PDFCite
Case ReportOpen accessIn the abstractImmunе-Mediated Myocarditis Associated with Leptospirosis in 6 Years Old Labrador RetrieverOleinikov Dmitrii, Letunoskaja AnnaAbout 6 years old, male Labrador retriever was presented for 10 days long weakness and fatigue. After diagnostic examinations, a preliminary diagnosis of Leptospirosis was suggested. Cardiologist consultation was advised. At admission, the dog was depressed, the visible mucosa was pale and capillary refilling time was slowed. Weak systolic murmur and rhythm disturbances were auscultated. Thoracic radiography revealed the accented … …American Journal of Animal and Veterinary Sciences, Vol. 13, Issue 3 · 4 Oct 2018 · 7,090 accessesView PDFCite
EditorialOpen accessIn the abstractAre we Able to Harness the Immunomodulatory Power of Cytokines for Novel Autoimmune Disease Treatments?Giuseppe Nocentini, Graziella Migliorati, Carlo RiccardiSince the end of the 1970s, interleukin 2 (IL-2) has been known as a key player in T cell expansion/activation (Watson et al., 1980). In the late 1980s, some groups used IL-2 to stimulate the immune systems of tumour patients (Jacobs et al., 1986). The idea seemed brilliant and several attempts were made, but the results were disappointing (Lim et … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 2 · 22 Oct 2015 · 7,625 accessesView PDFCite
EditorialOpen accessIn the abstractNeutrophil Extracellular Traps as Therapeutic Targets for Inflammatory DiseaseRory R. KoenenNeutrophilic granulocytes, or neutrophils are the most abundant circulating white blood cell and constitute a first line of defense against pathogens. They are characterized by a large polymorphic lobular nucleus and the presence of many secretory granules in their cytoplasm. Neutrophils are essential for a functional host defense, as is evidenced by the occurrence of severe infections in individuals with … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 25 Feb 2015 · 8,737 accessesView PDFCite
EditorialOpen accessIn the abstractTo NET or not to NETJadwiga JablonskaBranzk, N., A. Lubojemska, S.E. Hardison, Q. Wang and V. Papayannopoulos et al., 2014. Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens. Nat. Immunol.,15: 1017-1025. DOI: 10.1038/ni.2987 Brinkmann, V., U. Reichard, C. Goosmann, B. Fauler and A. Zychlinsky et al., 2004. Neutrophil extracellular traps kill bacteria. Science, 303: 1532-1535. DOI: 10.1126/science.1092385 Cools-Lartigue, J., … …American Journal of Immunology, Vol. 10, Issue 4 · 3 Dec 2014 · 8,383 accessesView PDFCite
Research ArticleOpen accessIn the abstractCLINICAL EXPERIENCE OF CANCER IMMUNOTHERAPY INTEGRATED WITH OLEIC ACID COMPLEXED WITH DE-GLYCOSYLATED VITAMIN D BINDING PROTEINEmma Ward, Rodney Smith, Jacopo J.V. Branca et al.Proteins highly represented in milk such as α-lactalbumin and lactoferrin bind Oleic Acid (OA) to form complexes with selective anti-tumor activity. A protein present in milk, colostrum and blood, vitamin D binding protein is the precursor of a potent Macrophage Activating Factor (GcMAF) and in analogy with other OA-protein complexes, we proposed that OA-GcMAF could demonstrate a greater immunotherapeutic activity … …American Journal of Immunology, Vol. 10, Issue 1 · 8 Mar 2014 · 13,186 accessesView PDFCite
Research ArticleOpen accessIn the abstractUltrastructural and Immunological Characterization of Hepatitis C Core Protein-DNA Plasmid ComplexesNelson Acosta-Rivero, Yaraima Aguilera, Viviana Falcon et al.Recently, it has been shown that a truncated HCV core (HCcAg) variant, covering the first 120 aa (HCcAg.120), interacts with plasmid DNA vaccine (pIDKE2), encoding the HCV structural proteins (HCcAg, E1 and E2). In the present work, HCcAg.120-pIDKE2 complexes, forming heterogeneous packaged structures, were visualized using a negative stain/rotary shadow technique. Interestingly, 72 hours after intramuscular injection of HCcAg.120-pIDKE2 complexes … …American Journal of Immunology, Vol. 2, Issue 3 · 30 Sep 2006 · 6,743 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntroduction of Three Complementary Technologies into Clinical Medicine: Development of New Diagnostic and Prognostic ParametersGernot P. Tilz, Marco Wiltgen, Ulrike Demel et al.Molecular medicine leads us to understand some diseases at the molecular level. Examples are the analysis of immune complexes and receptor - anti receptor compounds used in clinical medicine. Structural changes of some serum proteins occur in inflammation, neoplasie and autoimmunity. The detection and analysis of such structural modifications may offer a new field for the diagnosis, prognosis and therapy … …American Journal of Immunology, Vol. 2, Issue 1 · 31 Mar 2006 · 6,956 accessesView PDFCite