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22 results for “Diagnostic Strategies”
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Review ArticleOpen accessIn the keywordsDiagnosis of Pain in Small Companion AnimalsGiorgia della Rocca, Alice Catanzaro, Alessandra Di Salvo, Mary Ellen GoldbergIt is now widely accepted that animals are able to experience pain in a similar way to humans. Acute and/or chronic pain is associated not only with many surgical procedures, but also with various medical diseases, where pain may increase morbidity and mortality. Moreover, some types of pain (e.g., neuropathic pain) can be considered as an illness in themselves. Recognizing … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 2 · 15 Jun 2015 · 7,997 accessesView PDFCite
Literature ReviewOpen accessIn the abstractMicroRNAs in Atherosclerosis: Key Players, Diagnostic Potential, and Therapeutic OpportunitiesAnastasia V Poznyak, Stanislav Anatolievich Antonov, Ulyana V. Rozhkova et al.Atherosclerosis is a significant contributor to cardiovascular diseases, often progressing silently over many years before clinical symptoms manifest. The multifaceted pathogenesis of atherosclerosis, involving processes such as endothelial dysfunction and inflammation, presents challenges in early diagnosis and effective treatment. MicroRNAs (miRNAs), a class of non-coding RNA molecules with post-transcriptional gene regulation abilities, have emerged as potential key players in atherosclerosis … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 25 Jul 2026 · 740 accessesView PDFCite
Literature ReviewOpen accessIn the abstractIntracranial Atherosclerotic Disease: Treatment Potential and Diagnostic OpportunitiesAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Anton Yuvenalievich Postnov et al.Atherosclerosis, characterized by the accumulation of atherosclerotic plaques within large arteries, substantially increases the risk of cardiovascular events, including ischemic stroke. Intracranial atherosclerotic disease (ICAD) represents a particularly significant clinical threat given its strong association with ischemic stroke across multiple intracranial arterial territories. This review provides a comprehensive analysis of the pathogenesis, diagnosis, and management of intracranial atherosclerosis. Special attention … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 5 May 2026 · 1,093 accessesView PDFCite
Literature ReviewOpen accessIn the abstractPotential Therapies for Mitochondrial Diseases Caused by mtDNA MutationsAnastasia V. Poznyak, Nikolay A. Orekhov, Dmitry Felixovich Beloyartsev et al.Mitochondrial diseases, caused by mutations in mitochondrial DNA (mtDNA), present significant genetic and clinical complexities that challenge accurate diagnosis and treatment. This review examines the critical molecular mechanisms underlying these disorders, particularly the role of heteroplasmy, where mixtures of mutated and normal mtDNA influence disease severity, and the nuclear-mitochondrial DNA interactions that compound diagnostic and therapeutic challenges. The threshold effect, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,735 accessesView PDFCite
Review ArticleOpen accessIn the abstractTheory and Strategies of Atherosclerotic Renal Artery Stenosis TreatmentAnastasia V. Poznyak, Nikolay A. Orekhov, Gulalek Amanmyradovna Babayeva et al.Atherosclerosis is a disease that affects large arteries and contributes to the development of cardiovascular disease and adverse events. The main characteristic of this disease is the formation of plaques that narrow the lumen of the vessel. However, atherosclerosis is not the only cause of vasoconstriction. For example, various causes may be involved in renal artery stenosis, such as vasculitis … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 4 Jan 2026 · 1,859 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Integrated Nursing and Digital Droplet PCR on Bullous Dermatoid Conditions: A Randomized Controlled TrialConghui ChenBullous skin disease is an autoimmune disease characterized by the formation of blisters on the skin or mucous membrane, which seriously impairs the quality of life and overall health. Similar to the research on biomolecules (mechanics of protein interaction), cells (including cell membrane elasticity, cell adhesion, cytoskeletal dynamics, response to mechanical stimulation, cell deformation and cell endoforce transfer) and tissue … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 2 Jul 2026 · 985 accessesView PDFCite
Case SeriesOpen accessIn the abstractSurge of Mucormycosis in the Jaws Among COVID-19 Patients: A Case Series Highlighting the Role of Diabetes and ImmunosuppressionRam Mohan, Dharnappa Poojary, Sreehari Sreedhar et al.Mucormycosis is a life-threatening fungal infection caused by Mucorales species, frequently occurring in immunocompromised patients. This case series investigates the alarming rise in maxillary mucormycosis among post-COVID-19 patients in India and explores its correlation with uncontrolled diabetes and immunosuppressive conditions. This case series analyzed 52 patients, primarily with maxillary infections, to identify the association between COVID-19 and mucormycosis. Diagnostic methods … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 13 Apr 2026 · 1,346 accessesView PDFCite
Case ReportOpen accessIn the abstractFeline Dermatophytic Pseudomycetoma (Microsporum canis) Infection with Actinobactoer ursingii in a British Shorthair Cat: A Case Report in ThailandRatchanon Kusolsongkhrokul, Natapol PumipuntuDermatophytic pseudomycetoma is a rare, invasive fungal infection characterized by deep dermal and subcutaneous involvement of dermatophytes, uncommonly reported in cats. A 10-month-old, 2.8 kg, sexually intact female British Shorthair cat presented to a veterinary clinic with multiple abscessed nodules on the body, legs, and tail. Lesions contained yellow purulent discharge with granular material resembling fungal grains. Hematological and biochemical … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 4 · 18 Feb 2026 · 2,364 accessesView PDFCite
Literature ReviewOpen accessIn the abstractSigns of Predisposition to Atherosclerosis in Fetal DevelopmentAnastasia Vladimirovna Poznyak, Igor Alexandrovich Sobenin, Elizaveta M. Pleshko et al.Atherosclerotic Cardiovascular Disease (ASCVD) remains a significant global health concern, contributing to a substantial number of deaths worldwide. The etiology of this condition is multifaceted, influenced by a plethora of genetic and environmental determinants. Notably, certain risk factors and predictive markers associated with ASCVD may already present or emerge during the prenatal or neonatal period. Early recognition of these markers … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 15 Feb 2026 · 1,302 accessesView PDFCite
Research ArticleOpen accessIn the abstractImproving Diabetes Risk Prediction Using Ensemble Boosting and SMOTE-Based Class BalancingKittipol Wisaeng, Pankom Sriboonlue, Benchalak MuangmeesriAccurate diabetes prediction is vital for early intervention, optimized resource allocation, and minimizing long-term complications. This study presents a comparative evaluation of traditional and advanced machine learning models for diabetes classification using a structured clinical dataset. Seven baseline algorithms were assessed against five advanced ensemble methods: CatBoost, LightGBM, XGBoost, Voting Ensemble, and Stacking Ensemble. To improve algorithm learning, the Synthetic … …Journal of Computer Science, Vol. 22, Issue 1 · 1 Feb 2026 · 1,976 accessesView PDFCite