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Review Article · Open access · Published 4 January 2026

Theory and Strategies of Atherosclerotic Renal Artery Stenosis Treatment

Anastasia V. Poznyak1, Nikolay A. Orekhov1, Gulalek Amanmyradovna Babayeva2, Maria Andreevna Vergun2, Ksenia Olegovna Lapshina3, Vasily N. Sukhorukov4 & Alexander N. Orekhov1

American Journal of Biochemistry and Biotechnology, Volume 21, Issue 3, pp. 307–318 · doi.org/10.3844/ajbbsp.2025.307.318

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Abstract

Atherosclerosis is a disease that affects large arteries and contributes to the development of cardiovascular disease and adverse events. The main characteristic of this disease is the formation of plaques that narrow the lumen of the vessel. However, atherosclerosis is not the only cause of vasoconstriction. For example, various causes may be involved in renal artery stenosis, such as vasculitis and fibromuscular dysplasia. Nonetheless, atherosclerosis remains one of the major problems associated with it. By itself, renal artery stenosis leads to issues with blood supply to the kidneys and can be one of the causes of kidney failure. In our review, we examined in detail the pathology of atherosclerotic renal artery stenosis, focusing on diagnostic methods and treatment strategies.

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Poznyak, A. V., Orekhov, N. A., Babayeva, G. A., Vergun, M. A., Lapshina, K. O., Sukhorukov, V. N. & Orekhov, A. N. (2025). Theory and Strategies of Atherosclerotic Renal Artery Stenosis Treatment. American Journal of Biochemistry and Biotechnology, 21(3), 307–318. https://doi.org/10.3844/ajbbsp.2025.307.318

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Theory and Strategies of Atherosclerotic Renal Artery Stenosis TreatmentAmerican Journal of Biochemistry and Biotechnology · Volume 21, Issue 3 · pp. 307–318 · CC BY 4.0Download