Author

Nikolay A. Orekhov

Laboratory of Angiopathology, Institute of General Pathology and Pathophysiology, 8 Baltiiskaya Street, Moscow, Russia

3 articles in our journals

Articles where this person is an author, newest first. People are matched by their name as printed (no ORCID iD is recorded for them), not by name alone; search the name as text to find namesakes too.

Literature ReviewOpen accessCorrelation of Atherosclerosis and Osteoarthritis, the Role of Inflammation in the Pathogenesis of Osteoarthritis and AtherosclerosisAnastasia V. Poznyak, Nikolay A. Orekhov, Aleksandra Sergeevna Utkina et al.Cardiovascular Diseases (CVD) rank among the leading causes of death globally, accounting for a substantial proportion of mortality rates and affecting millions of individuals. Risk factors such as ageing, obesity, diabetes and a sedentary lifestyle contribute significantly to the prevalence of CVD. Osteoarthritis (OA), on the other hand, is one of the most common joint disorders, affecting a large segment … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 15 Feb 2026 · 1,769 accessesView PDF Cite

Literature ReviewOpen accessPotential Therapies for Mitochondrial Diseases Caused by mtDNA MutationsAnastasia V. Poznyak, Nikolay A. Orekhov, Dmitry Felixovich Beloyartsev et al.Mitochondrial diseases, caused by mutations in mitochondrial DNA (mtDNA), present significant genetic and clinical complexities that challenge accurate diagnosis and treatment. This review examines the critical molecular mechanisms underlying these disorders, particularly the role of heteroplasmy, where mixtures of mutated and normal mtDNA influence disease severity, and the nuclear-mitochondrial DNA interactions that compound diagnostic and therapeutic challenges. The threshold effect, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,735 accessesView PDF Cite

Review ArticleOpen accessTheory and Strategies of Atherosclerotic Renal Artery Stenosis TreatmentAnastasia V. Poznyak, Nikolay A. Orekhov, Gulalek Amanmyradovna Babayeva et al.Atherosclerosis is a disease that affects large arteries and contributes to the development of cardiovascular disease and adverse events. The main characteristic of this disease is the formation of plaques that narrow the lumen of the vessel. However, atherosclerosis is not the only cause of vasoconstriction. For example, various causes may be involved in renal artery stenosis, such as vasculitis … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 4 Jan 2026 · 1,859 accessesView PDF Cite