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11 results for “acute leukemia”
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Research ArticleOpen accessPhrase in the titleAge Difference in Immunophenotype of Acute LeukemiaKazunori Nakase, Mary Sartor, Kenneth BradstockWe examined the immunophenotype of 880 cases with acute leukemia and analyzed their age difference in relation to the morphological subtype and the karyotype. We divided the patients into 3 age groups: child (0-15 years), adult (16-59 years) and elderly (60 years and older) group. The diagnoses based on the French-American-British (FAB) criteria and the immunophenotype as follows: 453 patients … …American Journal of Immunology, Vol. 2, Issue 3 · 30 Sep 2006 · 6,941 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleUse of Novel Triphenyltin (IV) Dithiocarbamate Compounds in Assessing the Cytotoxicity and Mode of Cell Death of Acute Lymphoblastic Leukemia Cell Lines, CCRF CEM (CCL-119)Normah Awang, Nur Hidayah Hasrin, Nurul Farahana Kamaludin et al.Chemotherapy and radiotherapy are often used to treat Acute Lymphoblastic Leukemia (ALL). However, the resistance problem of treatment using the current drug in ALL patients has decreased the effectiveness of such therapy. Therefore, a study needs to be conducted to identify the potential of new anticancer agents. Organotin (IV) dithiocarbamate, an organometallic compound, causes toxic effects on cancer cells in … …OnLine Journal of Biological Sciences, Vol. 23, Issue 2 · 10 Mar 2023 · 5,159 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEmotion Regulation in Childhood with Cancer (Acute Lymphocytic Leukemia)Siti Yuyun Rahayu Fitri, Ediasri T. Atmodiwirjo, Winarini WilmanProblem statement: Emotion regulation in children with Leukemia actively undergoing a chemotherapy program has distinctive forms of regulation in the research on different cultures. Furthermore, the capability of children to regulate their emotions during a dynamic process involving frequent hospitalization and painful treatment is of increasing interest to researchers. This must also take into account how the role of culture … …Current Research in Medicine, Vol. 2, Issue 2 · 4 Oct 2011 · 7,583 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleGenetic Mutation Assessment of NPM1 Gene and Gene Expression of MDR1 in Iraqi Patients with Acute Myeloid LeukemiaAhmed Abduljabbar Suleiman, Ali Zaid Al-Saffar, Tamadher Abbas Rafaa, Hasan Abdulwahab JwadSince its discovery, mutations in NPM1 have been frequently associated with a large number of Acute Myeloid Leukemia (AML) patients. The vast majority of genetic changes were previously detected in exon 12, however little information report mutations in Nuclear Export Signal region (NES) of NPM1. Sequencing analysis included exon 2 and 3 for 75 Iraqi AML patients showed three SNPs, … …OnLine Journal of Biological Sciences, Vol. 18, Issue 1 · 11 Jan 2018 · 7,782 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleThe Triple Immune Argument; Surveillance/Evasion/ Senescence and the Increased Incidence of Acute Myeloid Leukemia Observed with AgeManar M. IsmailAML originates from genetic insults of hematopoietic stem and progenitor cells (HSPCs/HSCs) that was identified earlier as leukemia stem cells (LSCs). In quiescent state, trafficking immune cells are crucial for eradication of aberrant clones and obtaining balance between proliferation and apoptosis to maintain HSCs pool. Regulatory T-cells shield the HSCs from the inflammatory reactions by suppressing T- and B- cells. … …American Journal of Immunology, Vol. 13, Issue 4 · 22 Dec 2017 · 7,806 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHematologic Cancer Cell Detection and Classification Using Optimized VGG-19 with Stratified K-fold Cross-ValidationHema Patel, Himal Shah, Gayatri Patel, Atul PatelThe most prevalent pediatric blood malignancy is acute lymphoblastic leukemia (ALL). ALL is a lethal disease in which patients have a lower survival rate. Its prompt detection and precise categorization are essential for successful treatment. Manual microscopic diagnosis is laborious, prone to mistakes, and heavily reliant on specialized knowledge. With stratified 7-fold cross-validation, which assures an equal ratio of normal … …Journal of Computer Science, Vol. 21, Issue 11 · 24 Dec 2025 · 1,812 accessesView PDFCite
Research ArticleOpen accessIn the keywordsChildhood Cancer-a Hospital based study using Decision Tree TechniquesK. Kalaivani, R. ShanmugalakshmiProblem statement: Cancer is generally regarded as a disease of adults. But there being a higher proportion of childhood cancer (ALL-Acute Lymphoblastic Leukemia) in India. The incidence of childhood cancer has increased over the last 25 years, but the increase is much larger in females. The aim was to increase our understanding of the determinants of south Indian parental reactions … …Journal of Computer Science, Vol. 7, Issue 12 · 17 Oct 2011 · 7,057 accessesView PDFCite
Review ArticleOpen accessIn the abstractBioprospection of Endophytic Bacteria Isolated from Mangrove Ecosystems and their Potential Biotechnological ApplicationsAlfian Mubaraq, Mariani Sembiring et al.The unique mangrove ecosystem hosts a variety of microorganism activities, including the crucial role of endophytic bacteria. Microorganisms found in mangrove forests play an important role in maintaining the biosphere by uniting various living beings and can be vital for future biotechnological applications. The use of microorganisms in the field of biotechnology is prevalent for producing antimicrobials against pathogenic bacteria … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 16 Aug 2024 · 4,996 accessesView PDFCite
Case ReportOpen accessIn the abstractThe Diagnostic and Etiologic Challenge of Myocarditis in Oncologic Patients: Acute Myocarditis During Induction Treatment with All-Trans Retinoic AcidNúria Coma, Sergio Moral, Rosa Coll et al.Myocarditis is an inflammatory disease of the myocardium characterized by myocardial infiltration with inflammatory cells and non-ischemic myocytic necrosis. Its diagnosis is based on clinical, electrocardiogram, laboratory and echocardiographic parameters and also cardiac magnetic resonance or endomyocardial biopsy when possible. It occurs primarily as a result of infections that include viruses, parasites, bacteria and fungi. Moreover, there are other causes … …American Journal of Infectious Diseases, Vol. 17, Issue 3 · 7 Jun 2021 · 7,013 accessesView PDFCite
Research ArticleOpen accessIn the abstractATRA AS A POTENTIAL ANTIMETASTATIC AGENT IN COLORECTAL ADENOCARCINOMARobert Edwards, Kambiz Afrasiabi, Kehui WangThe family of Retinoic acid compounds have long been the subject of intense study and interest as chemo prophylactic agents. This dates back to their therapeutic effect in leukoplakia Where ATRA was shown to lead to the reversal of premalignant lesions and Subsequent reports on their use in metastatic colorectal adenocarcinoma and a vast array of other malignant disorders as … …OnLine Journal of Biological Sciences, Vol. 14, Issue 2 · 26 Mar 2014 · 7,344 accessesView PDFCite