Author

Normah Awang

Faculty of Health Sciences, Environmental Health and Industrial Safety Program, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Malaysia

11 articles in our journals

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Research ArticleOpen accessCytotoxicity and Apoptosis Prevailed by Tricyclohexyltin(IV) Dithiocarbamate Compounds Against Human Lung Carcinoma Cell Line (A549)Normah Awang, Nurul Amalina Abd Aziz, Nur Fatini Nordin, Nurul Farahana KamaludinIn Malaysia, lung cancer is a highly common kind of cancer and the leading cause of cancer-related deaths. This study examined the cytotoxicity of two new tricyclohexyltin(IV) dithiocarbamate compounds compounds, which are tricyclohexyltin(IV) N-methyl-N-benzyldithiocarbamate (C1) and tricyclohexyltin(IV) N-ethyl-N-benzyldithiocarbamate (C2), on lung carcinoma cell lines (A549) of humans. The cytotoxicity was assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) assay. Cell death mode … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 13 Jun 2024 · 4,622 accessesView PDF Cite

Research ArticleOpen accessUse of Novel Triphenyltin (IV) Dithiocarbamate Compounds in Assessing the Cytotoxicity and Mode of Cell Death of Acute Lymphoblastic Leukemia Cell Lines, CCRF CEM (CCL-119)Normah Awang, Nur Hidayah Hasrin, Nurul Farahana Kamaludin et al.Chemotherapy and radiotherapy are often used to treat Acute Lymphoblastic Leukemia (ALL). However, the resistance problem of treatment using the current drug in ALL patients has decreased the effectiveness of such therapy. Therefore, a study needs to be conducted to identify the potential of new anticancer agents. Organotin (IV) dithiocarbamate, an organometallic compound, causes toxic effects on cancer cells in … …OnLine Journal of Biological Sciences, Vol. 23, Issue 2 · 10 Mar 2023 · 5,159 accessesView PDF Cite

Research ArticleOpen accessCytotoxic Activity of Tinospora crispa Crude Extracts (Stem) Against K562 Human Leukemia CellsNormah Awang, Haziratul Iffah Ruzali, Rapidah Mohamad et al.Tinospora crispa (T. crispa) is traditionally used as an herbal medicine for treatment of gout and is an analgesic, anti-inflammatory and antihyperuricemic agent. Cytotoxicity of hexane, dichloromethane, ethanol and aqueous extracts of T. crispa stem against K562 cells was assessed. Crude extracts of T. crispa stem were obtained by sonication and maceration methods. T. crispa stem powder was macerated and … …OnLine Journal of Biological Sciences, Vol. 19, Issue 2 · 11 May 2019 · 7,870 accessesView PDF Cite

Research ArticleOpen accessCytogenetic Analysis among Train Depot Workers Exposed to Total Volatile Organic CompoundsNormah Awang, Siti Adillah Isah, Asmah HamidOccupational exposure to toxic chemicals such as Total Volatile Organic Compounds (TVOC) from diesel engine exhaust implicates genotoxic risk. The objective of this study was to determine the DNA damage among KL Sentral depot workers exposed to TVOC by means of cytogenetic analysis. Data were obtained partially from disseminated questionnaires and buccal cells samples were collected from a total of … …OnLine Journal of Biological Sciences, Vol. 15, Issue 2 · 12 Jun 2015 · 7,443 accessesView PDF Cite

Research ArticleOpen accessCYTOTOXICITY AND MODE OF CELL DEATH INDUCED BY TRIPHENYLTIN (IV) COMPOUNDS IN VITRONormah Awang, Zalila Abdul Aziz, Nurul Farahana Kamaludin, Kok Meng ChanA series of newly synthesized organotin (IV) with N-alkyl-N-phenyldithiocarbamate ligands namely triphenyltin (IV) ethylphenyldithiocarbamate (compound 1) and triphenyltin (IV) butylphenyldithiocarbamate (compound 2) were assessed for their cytotoxic effect against HT-29 human colon adenocarcinoma cells and human CCD-18Co normal colon cells. The cytotoxicity of these organotins in both cells was assessed using 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazholium bromide (MTT) assay upon 24 h treatment. … …OnLine Journal of Biological Sciences, Vol. 14, Issue 2 · 15 Mar 2014 · 8,746 accessesView PDF Cite

Research ArticleOpen accessThe Effectiveness of Organotin (IV) Benzylisopropyldithiocarbamate Compounds as Insecticide Against Aedes Aegypti Linn (Diptera: Culicidae) in LaboratoryHidayatulfathi Othman, Nor Atikah Kosnon, Normah Awang, Nurul Farahana KamaludinProblem statement: The widespread use of insecticides had resulted in insecticide resistance of vectors of dengue as well as polluting the environment. Organotin (IV) compounds had the potential to be developed as the insecticides to overcome the existing problem. Approach: The aim of this study was to examine the insecticidal effects which were larvicidal and adulticidal effects of organotin (IV) … …American Journal of Applied Sciences, Vol. 9, Issue 8 · 25 Jun 2012 · 6,980 accessesView PDF Cite

Research ArticleOpen accessStudy of Ambient and Indoor Air Quality in the Building Built on the Former LandfillAnuar Ithnin, Nazipah Zakaria, Nor Azura Sulong et al.Problem statement: The air quality study of PPR Taman Wahyu II, Selayang, Selangor was a residential project that was built on the former landfill site. The landfill site will produce landfill gases which can influence the air quality level in and outside the building. Approach: This air quality study also involving PPR Intan Baiduri, Batu Caves, Selangor as a control … …American Journal of Applied Sciences, Vol. 9, Issue 8 · 21 Jun 2012 · 6,989 accessesView PDF Cite

Research ArticleOpen accessRemoving Boron from an Aqueous Solution Using Turmeric Extract-Aided Coagulation-FlocculationAzhar Abdul Halim, Nur Hanani Thaldiri, Normah Awang, Mohd Talib LatifProblem statement: Boron exists in an environment naturally either through weathering of rocks or volcanic activity but due to anthropogenic activity, boron had been distributed widely into our surroundings. Boron was a problematic pollutant due to the difficulty to remove it from the water. Turmeric which had been widely used as a spice and traditional medicine, were investigated to determine … …American Journal of Environmental Sciences, Vol. 8, Issue 3 · 15 Jun 2012 · 8,329 accessesView PDF Cite

Research ArticleOpen accessEffects of Pollutant Diesel Fuels on Neurobehavioral Performance among Workers in Locomotive DepotAnuar Ithnin, Radiah Abu Hasan Shaari, Mazrura Sahani et al.Problem statement: Diesel fuel contains various combinations of hydrocarbons such as cyclohexane, n-hexane, benzene and toluene which can cause health problems in major exposure of that pollutant in locomotive depots. Studies were conducted to evaluate the exposure towards diesel fuel pollutant and the effect on neurobehavioral performances among workers in locomotive depots. Approach: Method used was questionnaire form and neurobehavioral … …American Journal of Environmental Sciences, Vol. 7, Issue 3 · 11 Jul 2011 · 7,458 accessesView PDF Cite

Research ArticleOpen accessSynthesis, Characterization and Biological Activities of Organotin (IV) Methylcyclohexyldithiocarbamate CompoundsNormah Awang, Ibrahim Baba, Bohari M. Yamin et al.Problem statement: The growing interest in the chemistry of sulphur donor ligands are due to their encouraging anticancer, antibacterial and antifungal activities as well as their widespread industrial application. Dithiocarbamates belong to this class and much attention has been paid to them. Approach: Novel organotin compounds with the molecular formula RmSn[S2CN(CH3)(C6H11)]4-m (where m = 2, R = CH3, C2H5; m … …American Journal of Applied Sciences, Vol. 8, Issue 4 · 18 Apr 2011 · 9,210 accessesView PDF Cite