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6 results for “Ulyana V. Rozhkova”

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Review ArticleOpen accessIn the author namesJAK Inhibitors for Rheumatoid Arthritis: Assessing Efficacy and Safety in TreatmentAnastasia V. Poznyak, Varvara A Orekhova, Natalia Vladimirovna Elizova et al.Rheumatoid Arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation, progressive joint destruction, and systemic complications. Dysregulated cytokine signaling through the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway plays a central role in RA pathogenesis, making JAK inhibitors an important therapeutic option. Tofacitinib, baricitinib, and upadacitinib are oral targeted synthetic disease-modifying antirheumatic drugs that interfere with … …OnLine Journal of Biological Sciences, Vol. 26, Issue 4 · 8 Oct 2026 · 412 accessesView PDFCite
Review ArticleOpen accessIn the author namesResveratrol for Atherosclerosis: Potential MechanismsAnastasia Vladimirovna Poznyak, Sergey Kozlov, Gulalek A Babayeva et al.Cardiovascular disease is a big problem around the world. At the heart of most serious cardiovascular diseases is such a pathology as atherosclerosis. Atherosclerosis is a complex set of interactions between inflammation, oxidative stress, lipid disorders, and other molecular, genetic, and lifestyle factors. It is this complexity and multicomponent nature of atherogenesis that make the treatment of atherosclerosis a non-trivial … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 11 Aug 2026 · 605 accessesView PDFCite
Research ArticleOpen accessIn the author namesAdipokines Overview: The Major Component of Immune DysregulationAnastasia Vladimirovna Poznyak, Daria Dmitryevna Borodko, Stanislav Anatolievich Antonov et al.Purpose of Review: Obesity is increasingly recognized as an immune endocrine disorder rather than only a metabolic condition. This review critically examines how adipokines particularly adiponectin, resistin, adipsin, and chemerin mediate the interplay between obesity and autoimmunity. Unlike previous reviews that broadly surveyed cytokines, our focus is on comparative roles of specific adipokines across multiple autoimmune diseases. Recent Findings: Evidence … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 11 Aug 2026 · 879 accessesView PDFCite
Literature ReviewOpen accessIn the author namesMicroRNAs in Atherosclerosis: Key Players, Diagnostic Potential, and Therapeutic OpportunitiesAnastasia V Poznyak, Stanislav Anatolievich Antonov, Ulyana V. Rozhkova et al.Atherosclerosis is a significant contributor to cardiovascular diseases, often progressing silently over many years before clinical symptoms manifest. The multifaceted pathogenesis of atherosclerosis, involving processes such as endothelial dysfunction and inflammation, presents challenges in early diagnosis and effective treatment. MicroRNAs (miRNAs), a class of non-coding RNA molecules with post-transcriptional gene regulation abilities, have emerged as potential key players in atherosclerosis … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 25 Jul 2026 · 740 accessesView PDFCite