Resveratrol for Atherosclerosis: Potential Mechanisms
Anastasia Vladimirovna Poznyak1, Sergey Kozlov2, Gulalek A Babayeva3, Vasily Nikolaevich Sukhorukov3,4, Alexander Nikolaevich Orekhov4, Stanislav Anatolievich Antonov2, Ulyana Vyacheslavovna Rozhkova1 & Vsevolod Vyacheslavovich Pavshintsev2 Show affiliations
- Institute for Atherosclerosis Research, Osennyaya Moscow, Russia
- Chazov National Medical Research Center of Cardiology of the Ministry of Health of the Russian Federation, Moscow, Russia
- Institute of Experimental Cardiology, National Medical Research Center of Cardiology, Moscow, Russia
- Institute of General Pathology and Pathophysiology, Laboratory of Angiopathology, Moscow, Russia
OnLine Journal of Biological Sciences, Volume 26, Issue 2, pp. 032 · doi.org/10.3844/ojbsci.2026.26.02.032
Abstract
Cardiovascular disease is a big problem around the world. At the heart of most serious cardiovascular diseases is such a pathology as atherosclerosis. Atherosclerosis is a complex set of interactions between inflammation, oxidative stress, lipid disorders, and other molecular, genetic, and lifestyle factors. It is this complexity and multicomponent nature of atherogenesis that make the treatment of atherosclerosis a non-trivial task. Currently, there are no entirely effective strategies for preventing or treating atherosclerosis. Nevertheless, various medications demonstrate varying degrees of effectiveness in relation to processes linked to atherogenesis. In this review, we reviewed a list of possible mechanisms that may contribute to the effectiveness of resveratrol against atherosclerosis.
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Poznyak, A. V., Kozlov, S., Babayeva, G. A., Sukhorukov, V. N., Orekhov, A. N., Antonov, S. A., Rozhkova, U. V. & Pavshintsev, V. V. (2026). Resveratrol for Atherosclerosis: Potential Mechanisms. OnLine Journal of Biological Sciences, 26(2), 032. https://doi.org/10.3844/ojbsci.2026.26.02.032
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