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16 results for “Osteoarthritis”
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Literature ReviewOpen accessEvery word in the titleCorrelation of Atherosclerosis and Osteoarthritis, the Role of Inflammation in the Pathogenesis of Osteoarthritis and AtherosclerosisAnastasia V. Poznyak, Nikolay A. Orekhov, Aleksandra Sergeevna Utkina et al.Cardiovascular Diseases (CVD) rank among the leading causes of death globally, accounting for a substantial proportion of mortality rates and affecting millions of individuals. Risk factors such as ageing, obesity, diabetes and a sedentary lifestyle contribute significantly to the prevalence of CVD. Osteoarthritis (OA), on the other hand, is one of the most common joint disorders, affecting a large segment … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 15 Feb 2026 · 1,769 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAssessment of Therapeutic Effects of Platelet-Rich Plasma in Knee Osteoarthritis: Possible Role of Inflammatory CytokinesMohammed H. Hassan, Sawsan Abuhamdah et al.Osteoarthritis (OA) is a multifactorial disease that commonly affects the knee. Tumor Necrosis Factor-α (TNF-α) regulates inflammation during OA. Macrophage Migration Inhibitory Factor (MIF) may be involved in the pathophysiology of arthritis. Platelet-Rich Plasma (PRP) may reduce pain associated with OA. The present study assessed the possible therapeutic effects of PRP in patients with OA of the knee with varying … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 2 · 15 Jun 2021 · 6,987 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleComparison of Improved Semi-Automated Segmentation Technique with Manual Segmentation: Data from the Osteoarthritis InitiativeHong Seng Gan, Khairil Amir SayutiManual segmentation is the standard procedure in osteoarthritis study. However, this method is infamous for being excessive, time consuming and exhaustive. In this study, we overcame the problem of excessive expert interaction reported in manual segmentation by developing a semi-automated random walks technique with computer-aided labelling system. To minimize expert interaction, non-cartilage seeds were generated by using computer. Then, random … …American Journal of Applied Sciences, Vol. 13, Issue 11 · 24 Oct 2016 · 7,363 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleTHE IMPACT OF ANTIOXIDANTS ON INFLAMMATION AND OXIDATIVE STRESS MARKERS IN OSTEOARTHRITIS RAT MODEL: SCANNING ELECTRON MICROSCOPE INSIGHTSEl Hassan Heidar, FareedF Al Faya, Waleed N. Hassan et al.Osteoarthritis (OA) is characterized by degradation of matrix and destruction of articular cartilage. Articular chondrocytes are solely responsible for the production and maintenance of the extracellular matrix. Therefore, chondrocyte disruption is implicated in cartilage degeneration. Numerous studies have shown that antioxidant treatments are promising therapeutics in cases of OA. This study was designedto examine whether vitamin E protects rat articular … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 19 May 2014 · 7,616 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAssociation of Polymorphism in Growth and Differentiation Factor 5 Gene with Osteoarthritis KneeAbhishek Mishra, Divya Sanghi, Amar Chandra Sharma et al.The present study investigated to identify the association of polymorphism in GDF-5 gene with osteoarthritis in North Indian population. In a case-control study, 300 cases with knee osteoarthritis and an equal number of age and gender matched healthy controls were included. Cases were diagnosed using the ACR Guidelines of Knee Osteoarthritis (KOA). Clinical symptoms were assessed with the knee specific … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 1 · 18 Mar 2013 · 9,417 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImpact of Dietary Polydextrose on Clinical Signs of Canine OsteoarthritisA. C. Beynen, D. H.J. Saris, L. De Jong et al.Problem statement: Osteoarthritis is an inflammatory joint disease associated with loss of cartilage matrix. There is suggestive evidence that the intake of polydextrose fiber has anti-inflammatory activity. It was reasoned that polydextrose may have a positive influence on canine osteoarthritis. Approach: A double-blind, placebo-controlled trial with privately owned dogs was carried out to assess the efficacy of STA-LITE® polydextrose in … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 3 · 5 Oct 2011 · 9,052 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleOral Administration of Gelatin Hydrolysate Reduces Clinical Signs of Canine Osteoarthritis in a Double-Blind, Placebo-Controlled TrialA.C. Beynen, H.W. Van Geene, H.V. Grim et al.Problem statement: There are indications that the intake of gelatin hydrolysate has a beneficial impact on the clinical signs of osteoarthritis in dogs. Data from a controlled trial were required to substantiate these indications. Approach: A double-blind, placebo-controlled trial with privately owned dogs was carried out to assess the efficacy of a preparation of gelatin hydrolysate in the treatment of … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 2 · 30 Jun 2010 · 18,245 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleInfluence of Dietary Beta-1,3/1,6-Glucans on Clinical Signs of Canine Osteoarthritis in a Double-Blind, Placebo-Controlled TrialA.C. Beynen, E. LegersteeProblem statement: There are indications for a beneficial effect of beta-1,3/1,6-glucans on the clinical signs of dogs with osteoarthritis. Data from a controlled trial were necessary to prove or disprove the indications. Approach: A double-blind, placebo-controlled trial with privately owned dogs was carried out to assess the efficacy of a preparation of beta-1,3/1,6-glucans in the treatment of osteoarthritis. With the … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 2 · 30 Jun 2010 · 10,105 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAssessment of Risk of Falls in Elderly Patients with Osteoarthritis of the Knee and Low Back PainVictor Hugo do Vale Bastos, Marco Antonio Araujo Leite, Marco Orsini et al.This study aimed identify which groups of elderly are at higher risk of falls, with osteoarthritis (OA), low back pain or both conditions. 29 elderly were distributed in three groups: OA of the Knee (OAK), Low Back Pain (LBP) and the two events concomitantly (OL). Evaluation tools applied were: Mini Mental State Examination (MMSE), Visual Analogue Scale (VAS), Western Ontario … …Current Research in Medicine, Vol. 3, Issue 2 · 30 Aug 2012 · 7,271 accessesView PDFCite
Case ReportOpen accessIn the keywordsNon-Specific Interstitial Pneumonia Overlapping Tuberculosis: A Diagnostic Challenge in ElderlyPradeep Chakaravarthy, Divanshee Sharma, Manjunath Totaganti et al.Non-Specific Interstitial Pneumonia (NSIP) is linked to numerous etiologies, including connective tissue diseases, certain drugs, HIV and idiopathic causes. We present a case of an 82-year-old woman with subacute onset shortness of breath as the presenting feature of Non-specific interstitial pneumonia. Chest imaging demonstrated bilateral infiltrates and tentatively diagnosed as NSIP and started on Tyrosine kinase inhibitor - Nintedanib. But … …American Journal of Infectious Diseases, Vol. 17, Issue 4 · 5 Jan 2022 · 6,168 accessesView PDFCite