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17 articles for “Metabolic Disorders”
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Research ArticleOpen accessPhrase in the titleHormonal and Metabolic Disorders of Human Immunodeficiency Virus Infection and Substance AbuseJag H. Khalsa, Frank Vocci, Adrian DobsThere are an estimated 200 million users of an illicit drug in the world today. In addition, an estimated 40 million people are infected with the human immunodeficiency virus (HIV) and an estimated 180 million people are infected with the hepatitis C virus (HCV). Both the use of an illicit drug and the co-occurrence of infections are associated with a … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,715 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSerum Ornithine Carbamoyltransferase Activity and Correlation with Fatty Liver in Dairy Cows with Displaced AbomasumKen Onda, Reiichiro Sato, Yosuke Sasaki et al.Ornithine Carbamoyltransferase (OCT) is a hepatocyte-specific enzyme; elevated serum activity indicates liver damage. Displaced abomasum frequently occurs around the time of parturition in dairy cattle and is associated with fatty liver. We analyzed serum OCT activities to investigate the relationship between displaced abomasum and fatty liver. Lactating Holstein cows, 75 clinically healthy and 22 with displaced abomasum, were used. Serum … …American Journal of Animal and Veterinary Sciences, Vol. 11, Issue 3 · 13 Jul 2016 · 7,660 accessesView PDFCite
Research ArticleOpen accessIn the abstractAdipokines Overview: The Major Component of Immune DysregulationAnastasia Vladimirovna Poznyak, Daria Dmitryevna Borodko, Stanislav Anatolievich Antonov et al.Purpose of Review: Obesity is increasingly recognized as an immune endocrine disorder rather than only a metabolic condition. This review critically examines how adipokines particularly adiponectin, resistin, adipsin, and chemerin mediate the interplay between obesity and autoimmunity. Unlike previous reviews that broadly surveyed cytokines, our focus is on comparative roles of specific adipokines across multiple autoimmune diseases. Recent Findings: Evidence … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 11 Aug 2026 · 879 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Intricate Relationship between Obesity and Type 2 DiabetesAnastasia V. Poznyak, Elizaveta M. Pleshko, Aleksandra S. Utkina et al.The rising prevalence of obesity and type 2 diabetes mellitus (T2DM) has emerged as one of the most pressing global public health challenges, profoundly impacting various demographic groups worldwide. This review synthesizes recent epidemiological data and explores the intricate biochemical mechanisms linking obesity to T2DM. We highlight the multifactorial nature of obesity, characterized by excessive adipose tissue, systemic inflammation, and … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 9 Aug 2026 · 455 accessesView PDFCite
Literature ReviewOpen accessIn the abstractCorrelation of Atherosclerosis and Osteoarthritis, the Role of Inflammation in the Pathogenesis of Osteoarthritis and AtherosclerosisAnastasia V. Poznyak, Nikolay A. Orekhov, Aleksandra Sergeevna Utkina et al.Cardiovascular Diseases (CVD) rank among the leading causes of death globally, accounting for a substantial proportion of mortality rates and affecting millions of individuals. Risk factors such as ageing, obesity, diabetes and a sedentary lifestyle contribute significantly to the prevalence of CVD. Osteoarthritis (OA), on the other hand, is one of the most common joint disorders, affecting a large segment … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 15 Feb 2026 · 1,769 accessesView PDFCite
Research ArticleOpen accessIn the abstractPost-COVID Impact Analysis and Effective Recommendation Solutions Over Risk Prediction Using Hybrid ModelBoddeti Jaggan Mohan Ravi Kumar, P. V. G. D. Prasad Reddy, G SrinivasThe COVID-19 pandemic (2019-2022) resulted in significant global mortality, largely attributed to the virus's unpredictable pathophysiology, rapid disease progression affecting multiple organ systems, and initial lack of effective treatments. This study systematically examines post-COVID-19 complications across major organ systems, including respiratory dysfunction, cardiovascular complications, renal disorders, musculoskeletal pain, gastrointestinal disturbances, neurological sequelae, alopecia, endocrine and metabolic dysregulation, and mental health … …Journal of Computer Science, Vol. 21, Issue 11 · 23 Dec 2025 · 1,643 accessesView PDFCite
Research ArticleOpen accessIn the abstractOat Pellets and Hay in Alpacas of Pastures of the Andean Zone, PerúMarcial Enciso Altamirano, Jimny Núñez Delgado, Alejandrina Sotelo-Méndez et al.The research was carried out at the INIA's Quimsachata experimental center in Puno, Peru; with the purpose of evaluating oat pellets and hay in Alpaca pastures in the Andean Zone. A total of Sixty-three 15-month-old female alpacas were used to evaluate their weight gain and feed consumption. The experiment was conducted with three treatments and 21 replicates under a completely … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 4 · 4 Mar 2025 · 5,583 accessesView PDFCite
Literature ReviewOpen accessIn the abstractUnveiling the Complex Relationship between Polycystic Ovary Syndrome and Cardiovascular Risk Factors: A Comprehensive ReviewAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina et al.Polycystic ovary syndrome remains a relatively unexplored endocrine disorder with significant implications for female health. Despite its prevalence and known associations with various metabolic disorders, the specific link between polycystic ovary syndrome and cardiovascular risk factors, particularly atherosclerosis, remains inadequately understood. This review aims to address the existing research gap by investigating the connection between polycystic ovary syndrome and cardiovascular … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 2 Oct 2024 · 4,607 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Review ArticleOpen accessIn the abstractUnveiling the Impact of Endogenous Sialidases on Human Non-Infectious Disease PathogenesisRaisa Sergeevna Surkova, Anastasia Vladimirovna Poznyak, Dmitry Alexandrovich Kashirskikh et al.In our review, we have compiled existing information regarding the role of endogenous sialidases (neuraminidases) in the initiation and development of various non-infectious processes in humans. Precisely, pathologies of the cardiovascular system, tumor formations, neurological and metabolic disorders, and hereditary diseases. Sialidases appeared to be widely involved in a variety of human pathologies. An increase or decrease in the enzymatic … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 10 Feb 2024 · 4,546 accessesView PDFCite