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23 results for “Melanoma”
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Research ArticleOpen accessEvery word in the titleHibiscus Flower Extract and Niacinamide Show Enhanced Whitening Effects in Mouse Melanoma Cells (B16F10)Jae Eun Choi, Tae Su Jang, Jung Min Park et al.Melanoma, a type of cancer that most often occurs on skin exposed to UV rays, is becoming increasingly common. Recent research has focused actively on using natural products. The goal of this study was to compare the melanin-inhibitory effects of Hibiscus (Hibiscus sabdariffa L.) flower Extract (HE) and Niacinamide (NA), a functional ingredient with whitening effects, on melanoma cells. The … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 1 · 9 Feb 2023 · 7,226 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Effect of Bovine Cartilage on the Growth of Mouse B16F10 Melanoma Cells in vitro and in vivoArax Tanelian, Dalal F. Jaber, Nayla S. Al Akl, Alexander M. AbdelnoorEarlier reports indicated that Bovine Cartilage (BC) had anti-tumor effects but only a few in vitro and in vivo investigations were conducted to assess its mechanism of action. The aim of this study was to investigate some of the proposed mechanisms of action of BC on mouse melanoma cells both in vitro and in vivo and to determine if its … …American Journal of Immunology, Vol. 12, Issue 3 · 26 Oct 2016 · 7,489 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMelanoma-Associated Suppression of the Dendritic Cell Lines DC2.4 and JawsiiKristian Michael Hargadon, Yonathan Tarekegne Ararso, Osric Anthony Forrest, Chad Mason HarteDendritic cells function as potent regulators of both innate and adaptive immunity to tumors and the regulatory activities of these cells are tightly linked to their maturation and activation status. Despite the critical role played by dendritic cells in the induction of anti-tumor immune responses, the number of dendritic cells that can be isolated from experimental animals is limiting and … …American Journal of Immunology, Vol. 8, Issue 4 · 3 Nov 2012 · 9,559 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMalignant Mucosal Melanoma of the Head and Neck Diagnosed in an Iranian Population over an 11-Year PeriodMaryam Assadat Hashemi Pour, M. Rad, M. R. Zarei, G. ChamaniProblem statement: Mucosal Melanoma of the Head and Neck (MMHN) is a rare lethal disease. This malignancy accounts for half of all mucosal melanomas, occurring mainly in the nasal cavity, oral cavity and pharynx. They appear with equal gender distribution and with a peak incidence in the age range 60-80 years. The aim of this study was to investigate incidence, … …American Journal of Applied Sciences, Vol. 6, Issue 8 · 31 Aug 2009 · 7,076 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleTheoretically Predicted Descriptors Based Quantitative Structure Activity Relationship Study of the Activity of Acridines Against B-16 MelanomaBahjat A. Saeed, Rita S. Elias, Sadiq M-H. Ismael, Kawkab A. HussainProblem statement: The probability of success and reducing time and coast in drug discovery process could be increased on the basis of QSAR techniques. The study involves the QSAR investigation of 20 bioactive acridines that have activity against Approach: Molecular descriptors, total energy, van der Waals volume, molecular volume, HOMO energy, HOMO-LUMO energy gap, polarizability, refractivity, bond angle of C8-N9-C2 … …American Journal of Applied Sciences, Vol. 8, Issue 8 · 18 Jul 2011 · 7,689 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA Comparative Study of Machine Learning Algorithms for Skin Cancer DetectionVineeth Victor, Amit Kumr Tyagi, Khushboo Tripathi et al.The skin is the largest organ in the human body, covering an area of around 20 square feet. Our skin keeps us safe from germs and the environment, helps us regulate our body temperature, and gives us the ability to feel touch, heat, and cold. More than 95 percent of all skin cancers are caused by ultraviolet (UV) radiation. UV … …Journal of Computer Science, Vol. 21, Issue 12 · 23 Jan 2026 · 1,859 accessesView PDFCite
Research ArticleOpen accessIn the keywordsDeep Learning Approaches for Early Detection of Skin Cancer Disease Detection Using Segmentation and Classification with Severity AnalysisPunam R. Patil, Ritu TandonThe utmost prevalent type of the disease, skin cancer claims millions of lives every year, poses a serious public health threat particularly melanoma, which is often fatal if not detected early. Early diagnosis is crucial, yet traditional methods frequently fall short due to image quality limitations and the complexity of visual differentiation. With an emphasis on severity analysis, this study … …Journal of Computer Science, Vol. 21, Issue 9 · 24 Nov 2025 · 2,051 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Effect of Lactobacillus Plantarum and Bacterial Peptidoglycan on the Growth of Mouse Tumors in vivo and in vitroArpa Aintablian, Dalal F. Jaber, Mary Ann Jallad, Alexander M. AbdelnoorSome members of the microbiota have been shown to be effective strategies for inhibiting tumor growth through stimulation of host anti-tumor immune responses. Anti-tumor immune effects were observed when Lactobacillus plantarum (Lp), a member of the gut microbiota, was used to treat colorectal cancer in mice. Moreover, constituents of bacteria, including peptidoglycan (PG), have been shown to exhibit tumoricidal effects. … …American Journal of Immunology, Vol. 13, Issue 3 · 23 Sep 2017 · 8,451 accessesView PDFCite
Review ArticleOpen accessIn the keywordsThe Duality of AIM2 Inflammasome: A Focus on its Role in Autoimmunity and Skin DiseasesMiriam CanaveseUnderstanding the inflammasome biology is one of the most exciting challenges in immuno-pharmacology. The role of the inflammasomes has been recognized in the host defense mechanism against invading pathogens and in the development of several conditions, such as cancer, auto-inflammatory, autoimmune, metabolic and neurodegenerative disorders. DNA recognition by the cells is a crucial immunological step leading to the initiation of … …American Journal of Pharmacology and Toxicology, Vol. 11, Issue 1 · 23 Apr 2016 · 7,369 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn vitro Antioxidant and Cytoprotective Potentials of Postbiotic ProbioMETA G55Xinyi Song, Ga Yeon Kim, Young Ki Lee, Jae Kyung KimStudies have demonstrated the favorable beneficial impact of probiotic metabolites on the skin. However, the use of postbiotics for skincare is a relatively new field despite their high safety and stability, which guarantee a longer shelf life. The postbiotic ProbioMETA G55(G55) is a skincare raw material, but none of the studies have evaluated the antioxidant capacity of G55 in skin … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 3 · 7 Aug 2023 · 4,953 accessesView PDFCite