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Research Article · Open access · Published 23 January 2026

A Comparative Study of Machine Learning Algorithms for Skin Cancer Detection

Vineeth Victor1, Amit Kumr Tyagi2, Khushboo Tripathi3, Kajal Rai4, Ravi Prakash Chaturvedi3, Lalan Kumar4 & Pragya Siddhi4

Journal of Computer Science, Volume 21, Issue 12, pp. 2928–2939 · doi.org/10.3844/jcssp.2025.2928.2939

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Abstract

The skin is the largest organ in the human body, covering an area of around 20 square feet. Our skin keeps us safe from germs and the environment, helps us regulate our body temperature, and gives us the ability to feel touch, heat, and cold. More than 95 percent of all skin cancers are caused by ultraviolet (UV) radiation. UV radiation is emitted by the sun, although it is unrelated to sunshine or heat, as many people believe. The key factor that causes skin cells to become cancer cells is exposure to UV radiation. Overexposure to UV radiation causes almost all skin cancers (about 99 percent of non-melanoma skin cancers and 95 percent of melanoma). Sunburn has been shown to play a significant role in the development of melanoma, the most dangerous of the three most common types of skin cancer. According to research, UV rays can alter a gene that suppresses tumours, increasing the risk of sun-damaged skin cells turning into skin cancer. Melanoma is the worst form of skin cancer and one of the most common cancers. Melanoma rates are quickly increasing, particularly in young people and have increased in the previous 30 years, despite the fact that cancer rates for other prevalent cancers have decreased. Melanoma is highly treatable if found early. While late-stage melanoma treatments are quickly improving, prevention and early detection remain the best treatment options. Our study delves into the critical realm of skin cancer detection with the aim of evaluating the efficacy of various cutting-edge machine learning algorithms including Random Forest, Support Vector Machine, and CNN is exploring skin cancer patterns. Through careful examination, utilizing metrics like accuracy, precision, and recall, we highlight the superior performance of SVC and CNN. Our research not only contributes to the ongoing studies in skin cancer detection but also underscores the potential of advanced computational strategies in augmenting preventive healthcare strategies.

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Open access. This article is licensed under a Creative Commons Attribution 4.0 International Licence (CC BY 4.0), as printed on the article, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original authors and the source. No permission is needed.

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Victor, V., Tyagi, A. K., Tripathi, K., Rai, K., Chaturvedi, R. P., Kumar, L. & Siddhi, P. (2025). A Comparative Study of Machine Learning Algorithms for Skin Cancer Detection. Journal of Computer Science, 21(12), 2928–2939. https://doi.org/10.3844/jcssp.2025.2928.2939

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Volume 21, Issue 12
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A Comparative Study of Machine Learning Algorithms for Skin Cancer DetectionJournal of Computer Science · Volume 21, Issue 12 · pp. 2928–2939 · CC BY 4.0Download