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21 results for “Marco Ruggiero”
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EditorialOpen accessIn the author namesIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,285 accessesView PDFCite
Research ArticleOpen accessIn the author namesGenetic Analysis of Bifidobacteriaceae in a Fermented Milk and Colostrum Product in Relation to Immune FunctionMarco RuggieroThis study investigates the microbial composition of a commercially available Swiss fermented milk and colostrum product with a history of use in chronic condition management since 2014. The analysis, performed using the Axiom Microbiome Array, identified a high number of targets corresponding to microbial species classified as probiotics belonging to the Bifidobacteriaceae family. The array provided 28 unique targets, each … …American Journal of Immunology, Vol. 19, Issue 1 · 2 Aug 2024 · 9,054 accessesView PDFCite
Literature ReviewOpen accessIn the author namesOn the Natural Intelligence and Consciousness of the Immune System and its Relationship with the BrainMarco Ruggiero, Akira HiratsukaIn this article, we consider the relationship between the brain and the immune system in the context of the Orchestrated Objective Reduction (Orch OR) theory of consciousness. Orch OR is a theory that postulates that consciousness arises from quantum computations occurring inside microtubules. The immune system is capable of acquiring, learning, and remembering information, thus showing all the attributes of … …American Journal of Immunology, Vol. 19, Issue 1 · 17 Apr 2024 · 11,436 accessesView PDFCite
Research ArticleOpen accessIn the author namesEffects of a Topical Composition of GABA and Microbial Chondroitin Sulfate on Mental Calmness and Brain FunctionMarco RuggieroThis article describes a novel topical composition constituted by Gamma-Aminobutyric Acid (GABA) and microbial chondroitin sulfate. This composition, formulated by the author and manufactured in a certified facility in the United States of America, exhibits potential for non-invasive intervention in anxiety management, sleep quality enhancement and promotion of brain-related functions like meditation and nonlocal consciousness. The core component comprises GABA, … …American Journal of Immunology, Vol. 19, Issue 1 · 8 Mar 2024 · 11,681 accessesView PDFCite
Research ArticleOpen accessIn the author namesRelease of Endogenous Chondroitin Sulfate and Heparin as Consequence of Dysregulated Proteolysis in COVID-19Marco RuggieroInfection by severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), the pathogen responsible for COVID-19, is associated with immune-mediated responses that lead to dysregulated activation of proteolytic enzymes; these contribute to damage to the endothelium, thrombosis, hypercoagulability and other hematologic complications that include thrombotic thrombocytopenia, a complication of severe COVID-19 as well as a potentially fatal adverse effect of COVID-19 vaccination. … …American Journal of Immunology, Vol. 17, Issue 1 · 29 Dec 2021 · 7,691 accessesView PDFCite
Research ArticleOpen accessIn the author namesExperimental Evidence for the Role of Natural Radioactivity in Influencing Viability of Commensal MicroorganismsMarco RuggieroTo investigate the feasibility of culturing edible microbes, classified as probiotics for human consumption, in commercially available, naturally radioactive, mineral water; to compare their viability with that of the same microbes cultured in deuterium-depleted water. A diversified array of probiotics was cultured in two different naturally radioactive mineral waters, or in deuterium-depleted water in order to assess the effects of … …American Journal of Immunology, Vol. 17, Issue 1 · 26 May 2021 · 8,745 accessesView PDFCite
Case ReportOpen accessIn the author namesEffects on the Immune System of a Three-Month Consumption of an Extremely Diverse Probiotic Yogurt: Decrease of Serum Alpha-N-Acetylgalactosaminidase Activity, Detoxification and Gut Microbiota NormalizationJerry Blythe, Marco RuggieroIn this study, we describe the changes associated with the consumption of an extremely biodiverse probiotic yogurt in a 55-year-old female from South Vietnam. In August 2019, the subject voluntarily embarked on a three-month nutritional experience and decided to share her results with the goal of advancing scientific knowledge in the field of nutritional health. Consumption of this biodiverse probiotic … …American Journal of Immunology, Vol. 16, Issue 1 · 22 Oct 2020 · 9,699 accessesView PDFCite
Case ReportOpen accessIn the author namesConsumption of an Extremely Biodiverse Probiotic and a Supplement based on Microbial Chondroitin Sulfate is Associated with Very Low Serum Alpha-N-acetylgalactosaminidase (Nagalase) Activity and Decrease of C-reactive Protein ValuesMichael Carter, Stefania Pacini, Marco RuggieroWe describe the case of a 57-years-old male healthy professional who added to his nutritional plan a novel, extremely biodiverse, probiotic and a supplement based on microbial chondroitin sulfate, vitamin D3 and ultrapure phosphatidylcholine to improve his healthy life expectancy. After three months of such a nutritional regimen, serum alpha-N-acetylgalactosaminidase (nagalase) activity was 0.40 that is a value below the … …American Journal of Immunology, Vol. 16, Issue 1 · 22 Apr 2020 · 13,055 accessesView PDFCite
Research ArticleOpen accessIn the author namesColor Doppler Evaluation of Isovolumetric Relaxation Time and of Signals Arising from Axons of the Median Nerve as a Means to Evaluate Mitochondrial Functionality in the Context of Immunotherapy of Cancer and Chronic Conditions Associated with Mitochondrial DysfunctionStefania Pacini, Marco RuggieroReactive Oxygen Species (ROS) arising from the disruption of mitochondrial respiration act as endogenous mutagens and tumor promoters. When production of ROS exceeds the capacity of DNA repair mechanisms, random mutations and aneuploidy ensue, thousands of genes become unbalanced and genetic/epigenetic chain reactions lead to progressive aneuploidy with only two outcomes: karyotypes so altered that are not viable or karyotypes … …American Journal of Immunology, Vol. 15, Issue 1 · 12 Oct 2019 · 9,700 accessesView PDFCite