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18 results for “Infection models”
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Research ArticleOpen accessEvery word in the titleThe Effects of Costus Root Aqueous Extract against Schistosomiasis, Liver Damage and Oxidants in Mouse Models of Schistosoma mansoni InfectionAreej Jameel M. AlghabbanSchistosomiasis is one of the major human parasitic diseases in many developing countries that causing chronic ill health in humans. The present work aimed to study the possible curative role of Costus (Saussurea lappa) root extract against Schistosoma mansoni infection induced liver toxicity, cytokines, oxidative stress and DNA damage in mice. 40 adult male micewere divided into four groups (G1, … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 15 Apr 2021 · 6,409 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEfficacy and Characteristics of different Methods of Coccidiosis Infection in Broiler ChickensM.A. Elmusharaf, H.E. Mohamed, A. Alhaidary, A.C. BeynenProblem statement: Different methods of experimental infection of broiler chickens with Eimeria species have been described in the literature. These methods had not been compared and contrasted so as to contribute to the selection of the most appropriate model of coccidiosis in broiler chickens. Identifying such a model was important to speed up the screening of potential coccidiostatics. Approach: In … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 1 · 31 Mar 2010 · 8,839 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Novel Characterization of the Incidence Term in Epidemic Models: Interpretation of the Resulting Basic Reproduction Number in Terms of Healthcare AccessibilityFrancis BenyahWe propose a novel characterization of the incidence term in mathematical epidemic models. This new characterization takes into consideration the fact that at any given time, only a proportion $\kappa \ (0 \, \le \, \kappa \, \le \, 1)$, of infectives have access to healthcare. Infectives without access remain untreated and therefore, become reservoirs for new transmissions.The proposed incidence … …Journal of Mathematics and Statistics, Vol. 22, Issue 1 · 1 Oct 2026 · 582 accessesView PDFCite
Research ArticleOpen accessIn the abstractInvestigating Campylobacter Spp. in Mekong Delta Duck Farms: Prevalence, Risk Factors, and Antibiotic ResistanceNguyen Vu Thuy Hong Loan, Le Trung Kien, Do Ngoc Yen Phuong et al.Campylobacter spp. is a leading cause of gastroenteritis worldwide, contributing to significant health and economic burdens, especially in poor hygiene practices. Investigating this bacterium's prevalence and antibiotic resistance in ducks from the Mekong Delta is essential, as the region's extensive duck farming industry presents a potential risk for transmission to humans through the food chain. During August 2024 to February … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 4 · 8 Feb 2026 · 1,615 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrediction and Analysis of COVID-19 Cases using Regression Models: A Descriptive Case Study of IndiaIsmail KeshtaThe Coronavirus(SARS-CoV-2) is a respiratory illness that emerged in Wuhan, China, on December31, 2019, according to reports by the World Health Organization (WHO). Hospitalrecords in India indicate that COVID-19 hospitalizations in the second wave ofCOVID-19 more than doubled those in the first wave. Limited studies have beenconducted to establish the extent to which the second wave of COVID-19increased the infection … …Journal of Computer Science, Vol. 18, Issue 10 · 12 Oct 2022 · 6,156 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn silico and in vitro Structural Analysis on the Interaction of Calmodulin and Calmodulin-Binding Motif of FKBP35 from Plasmodium knowlesiSazlinawatie Aladin, Cahyo Budiman et al.FK506-binding protein 35 (FKBP35) is a peptidyl-prolyl cis-trans isomerase found in Plasmodium knowlesi, a zoonotic malaria parasite responsible for concerning cases of malaria infection in East Malaysia. This protein contains a segment known as the calmodulin-binding motif (Pk-CBM), which is predicted to facilitate interaction with calmodulin from P. knowlesi (Pk-CaM). Although this interaction is considered promising for future antimalarial drug … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 10 Mar 2025 · 4,846 accessesView PDFCite
EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,862 accessesView PDFCite
EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,281 accessesView PDFCite
Research ArticleOpen accessIn the abstractModulation of IFN-γ, IL-4 and IL-17 Cytokines is Related to Parasitemia Control in Mice Infected by Trypanosoma cruzi and Treated with BiotherapyFabiana Nabarro Ferraz, Franciele Karina da Veiga, Denise Lessa Aleixo et al.The study of biotherapies as an intervention in experimental models of infection is a possible means to understand the effects of these highly diluted medications. The present study evaluated the immunological and parasitological effects of biotherapies that were prepared from mouse serum that was uninfected (sarcode: BSNI13cH group) and chronically infected with the Y strain of T. cruzi (nosode: BSI13cH … …OnLine Journal of Biological Sciences, Vol. 15, Issue 4 · 30 Oct 2015 · 7,357 accessesView PDFCite
Research ArticleOpen accessIn the abstractPlasmodium Pre-Erythrocytic Stages: Biology, Whole Parasite Vaccines and Transgenic ModelsKota Arun Kumar, Satish MishraMalaria remains one of the world’s worst health problems, which causes 216 million new cases and approximately 655,000 deaths every year WHO World Malaria Report, 2011. Malaria transmission to the mammalian host is initiated through a mosquito bite that delivers sporozoites into the vertebrate host. The injected sporozoites are selectively targeted to liver which is the first obligatory step in … …American Journal of Immunology, Vol. 8, Issue 3 · 13 Sep 2012 · 8,263 accessesView PDFCite