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46 articles for “Genetic Mechanism”
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Research ArticleOpen accessIn the keywordsDose-Dependent Neurotoxic Effects of Monosodium Glutamate and its Potential Genetic Transmission in MiceYanan Zou, Qiong Liang, Lu Liu et al.This study aimed to preliminarily investigated the neurotoxic effects of monosodium glutamate on mice and their pups, and the potential possibility of a genetic mechanism influencing the pups. In this study, mice were given different doses of Monosodium Glutamate (MSG) at doses of 2.0 or 4.0 g/kg body weight for 10 continuous days, and its impacts on both the mice … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 14 Nov 2025 · 3,031 accessesView PDFCite
Research ArticleOpen accessIn the keywordsMulti-Objective Optimization of FRP Jackets for Improving the Seismic Response of Reinforced Concrete FramesCorrado Chisari, Chiara BedonIn this study, a multi-objective Genetic Algorithm (GA) optimization procedure is proposed for the seismic retrofitting of Reinforced Concrete (RC) building frames via Fiber-Reinforced Polymer (FRP) jackets. The optimization problem is solved via numerically efficient but accurate Finite-Element (FE) models able to take into account the strengthening and ductility increase contribution for a given FRP jacketing configuration. Based on a … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 3 · 27 Sep 2016 · 8,825 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPerformance Analysis of Multi Clustered Parallel Genetic Algorithm with Gray ValueP. Vishnu Raja, V. Murali BhaskaranProblem statement: Encoding is one of the major factors in genetic algorithms, for a complex problem the optimality for the problem is determined. The encoding mechanism is the initial step which forms the chromosome to form the best fit individuals in the entire population. The proposed method tries to encode the initial population by the binary encoding and by gray … …American Journal of Applied Sciences, Vol. 9, Issue 8 · 28 Jun 2012 · 7,163 accessesView PDFCite
Research ArticleOpen accessIn the keywordsOptimization of Test Scheduling and Test Access for ITC-02 SOC Benchmark CircuitsP. Sakthivel, R. Delhi Babu, P. NarayanasamyProblem statement: This study presented the optimized test scheduling and test access for ITC-02 SOC benchmark circuits using genetic algorithm. In the scheduling procedure of SOC, scheduling problem was formulated as a sequence of two problems and solved. Approach: Test access mechanism width was partitioned into two and three partitions and the applications of test vectors and test vector assignments … …Journal of Computer Science, Vol. 5, Issue 4 · 30 Apr 2009 · 7,315 accessesView PDFCite
Research ArticleOpen accessIn the abstractExplainability Aware Heterogeneous Temporal Graph Transformer for Automated Genetic Disorder Detection from Genomic DataPuvaneswari Subramaniapillai, Indirani Govindasamy, Revathy GurumurthyGenetic disorders affect millions worldwide, posing major challenges for accurate diagnosis and effective treatments. New developments in genomic technologies, especially Next-Generation Sequencing (NGS), have enhanced the classification of genetic modification and improved diagnostic abilities. Moreover, the Machine Learning (ML) and Deep Learning (DL) methods emerged as efficient tools for evaluating the intricate genomic data and determining the patterns, which can … …Journal of Computer Science, Vol. 22, Issue 11 · 14 Oct 2026 · 566 accessesView PDFCite
Research ArticleOpen accessIn the abstractMultivalent Optimizer-Based Hybrid Genetic Algorithm for Task Scheduling in Cloud ApplicationsMeena Malik, Bhavna Gupta, Chander Prabha et al.Cloud computing platforms provide on-demand online services without the need for direct user management. Generally, big clouds distribute functions over multiple data centers at distant locations. The major facilities offered by clouds are based upon virtual machines which provide benefits in terms of low scheduling cost, improved accessibility and availability of cloud services. While transferring the tasks for effective scheduling, … …Journal of Computer Science, Vol. 21, Issue 2 · 31 Dec 2024 · 4,900 accessesView PDFCite
Literature ReviewOpen accessIn the abstractPotential Therapies for Mitochondrial Diseases Caused by mtDNA MutationsAnastasia V. Poznyak, Nikolay A. Orekhov, Dmitry Felixovich Beloyartsev et al.Mitochondrial diseases, caused by mutations in mitochondrial DNA (mtDNA), present significant genetic and clinical complexities that challenge accurate diagnosis and treatment. This review examines the critical molecular mechanisms underlying these disorders, particularly the role of heteroplasmy, where mixtures of mutated and normal mtDNA influence disease severity, and the nuclear-mitochondrial DNA interactions that compound diagnostic and therapeutic challenges. The threshold effect, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,735 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Integrated Nursing and Digital Droplet PCR on Bullous Dermatoid Conditions: A Randomized Controlled TrialConghui ChenBullous skin disease is an autoimmune disease characterized by the formation of blisters on the skin or mucous membrane, which seriously impairs the quality of life and overall health. Similar to the research on biomolecules (mechanics of protein interaction), cells (including cell membrane elasticity, cell adhesion, cytoskeletal dynamics, response to mechanical stimulation, cell deformation and cell endoforce transfer) and tissue … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 2 Jul 2026 · 985 accessesView PDFCite
Review ArticleOpen accessIn the abstractUnraveling the Mechanisms of Plant Structural Defenses against Insect PestsAroni Preya Biswas, Roksana Al Nafiu Insha, Md. Khairul Mazed et al.Plants employ a variety of physical, chemical, and genetic strategies to defend against herbivore attacks. These biochemical defense mechanisms are complex and dynamic, encompassing both direct and indirect responses. Defense-related chemicals, whether constitutive or induced by herbivore damage, significantly influence herbivore feeding behavior, growth, and survival. Plant defense systems impact herbivore nutrition, development, and survival, highlighting the importance of chemical … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 7 Jan 2025 · 5,793 accessesView PDFCite
Review ArticleOpen accessIn the abstractMechanistic Insights of Actions of Metal Nanoparticles on Multidrug-Resistant BacteriaSeham S. Alzahrani, Hani Mohammed Ali, Mohamed M. AhmedMultidrug-Resistant bacteria (MDR) are the most serious threat to public health. The number of infections caused by resistant strains is on the rise all over the world. At this time, new techniques for developing antimicrobial drugs are becoming necessary. Metallic Nanoparticles (MNPs) in the biomedical field are one of the most promising methods to overcome antibiotic resistance. Nanoparticles have recently … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 22 Jun 2021 · 6,374 accessesView PDFCite