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10 results for “Dyslipidemia”

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Research ArticleOpen accessEvery word in the titlePathophysiology of Adipocyte Defects and Dyslipidemia in HIV Lipodystrophy: New Evidence from Metabolic and Molecular StudiesAshok Balasubramanyam, Rajagopal V. Sekhar, Farook Jahoor et al.Despite a burgeoning mass of descriptive information regarding the epidemiology, clinical features, body composition changes, hormonal alterations and dyslipidemic patterns in patients with HIV lipodystrophy syndrome (HLS), the specific biochemical pathways that are dysregulated in the condition and the molecular mechanisms that lead to their dysfunction, remain relatively unexplored. In this paper, we review studies that detail the metabolic basis … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,608 accessesView PDFCite
Review ArticleOpen accessIn the keywordsRole of HDL in Atherogenesis: Cholesterol and AtheroprotectionAnastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Victor Yurievich Glanz et al.Atherosclerosis is a major global health burden, responsible for a significant proportion of cardiovascular morbidity and mortality worldwide. Its high prevalence and severe clinical consequences have made it a subject of extensive research. Despite considerable advances, the complexity of its pathogenesis continues to hinder the development of effective preventive strategies and therapeutic interventions. Current evidence implicates chronic inflammation, dysregulated lipid … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 3 Apr 2026 · 1,476 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Lipid-Lowering Efficacy of Switching Within Non-Nucleoside Reverse Transcriptase Inhibitors in HIV-Infected PatientsA.M. Bain, K.D. Payne, A.P. Rahman et al.The objective of present research is to evaluate the lipid lowering efficacy and safety of switching within non-nucleoside reverse transcriptase inhibitors (NNRTI) in HIV-infected patients. This is a multicenter, retrospective study utilizing a comprehensive electronic patient registry to identify all adult HIV-infected patients seen from October 1, 1998 through October 1, 2006, who substituted efavirenz for nevirapine (EFV→NVP) or vice-versa … …American Journal of Infectious Diseases, Vol. 4, Issue 2 · 30 Jun 2008 · 6,743 accessesView PDFCite
Research ArticleOpen accessIn the abstractsuPAR as an Inflammatory and Preclinical Atherosclerotic Marker in Hypovitaminosis DShravan Ajith Panchwadkar, Sudha Kuthethur, Neelam Manjunath Pawar et al.The mechanistic link between inflammation and atherosclerosis highlights the critical role of immune modulation in cardiovascular disease. The soluble urokinase plasminogen activator receptor (suPAR), an immune-derived factor, has recently emerged as a non-specific inflammatory marker across chronic diseases and infections. All cells within the atherosclerotic arterial wall can express uPAR and release urokinase, which plays a key role in the … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 30 Mar 2026 · 1,122 accessesView PDFCite
Research ArticleOpen accessIn the abstractExploring the Role of Vitamin B12 as an Anti-atherogenic and Anti-inflammatory Agent in Apparently Healthy Adults With Hypovitaminosis DShravan Ajith Panchwadkar, Sudha Kuthethur, Sowndarya Kollampare, Neelam Manjunath PawarVitamin B12 deficiency is associated with metabolic changes like methyl malonic acidemia and hyperhomocystinemia eventually leading to atherosclerosis. Dyslipidemia and vitamin D (vit D) deficiency are independent risk factors of CVD. This study aims to explore the interrelationship between inflammatory markers, adverse lipid profile and vitamin B12 in hypovitaminosis D. Since, atherosclerosis is an inflammatory condition we have investigated CRP … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 11 Jul 2025 · 3,326 accessesView PDFCite
Literature ReviewOpen accessIn the abstractUnveiling the Complex Relationship between Polycystic Ovary Syndrome and Cardiovascular Risk Factors: A Comprehensive ReviewAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina et al.Polycystic ovary syndrome remains a relatively unexplored endocrine disorder with significant implications for female health. Despite its prevalence and known associations with various metabolic disorders, the specific link between polycystic ovary syndrome and cardiovascular risk factors, particularly atherosclerosis, remains inadequately understood. This review aims to address the existing research gap by investigating the connection between polycystic ovary syndrome and cardiovascular … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 2 Oct 2024 · 4,607 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssociation Study between Different Anthropometric Measures and other Clinical Markers in Saudi Female Students at King Abdulaziz UniversityAsmaa H Almalki, Maha ST Saad, Shahad S Alzahrani et al.This research addresses nutritional status, Body Mass Index (BMI), Waist-Hip Ratio (WHR), physical activity and Blood Pressure (BP) among female students attending King Abdul-Aziz University (KAU) and correlates the changes in BMI and WHR with Systolic Blood Pressure (SBP) and diastolic blood pressure (DBP). Saudi female students (N = 232) aged 18 to 27 years old were recruited over two … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 1 · 21 Jan 2020 · 7,785 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessment of Cardio-Metabolic Risk Factors among Young Adult FemalesSwati Dhruv, Uma Iyer, Kusum BhattProblem statement: Over the past two decades there has been a striking increase in the number of people with metabolic syndrome in developing countries. The current study was thus undertaken to map the prevalence of Metabolic Syndrome (MS) and to assess the cardio-metabolic risk factors among young adult females (n = 1303) aged 18-26y from four girls hostel of the … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 23 Feb 2012 · 7,874 accessesView PDFCite
Research ArticleOpen accessIn the abstractEfficacy of Pravastatin in Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) and Protease Inhibitor (PI)-based HAART in HIV-Infected PatientsSusan A. Eaton, Anita P. Rahman, Sean T. Nguyen et al.Pravastatin has generally been considered a safe and effective option for HIV-infected patients on highly active antiretroviral therapy (HAART). However, pravastatin concentrations are known to significantly decrease with concomitant efavirenz (EFV) use. Currently there are no studies determining if these reductions in pravastatin possibly translate into an attenuation of its lipid lowering efficacy when used in HIV-infected patients on non-nucleoside … …American Journal of Infectious Diseases, Vol. 4, Issue 2 · 30 Jun 2008 · 6,959 accessesView PDFCite
Research ArticleOpen accessIn the abstractCardiovascular Risk Factors in North Indians: A Case-Control StudyVivek P. Singh, V. Ramesh, Sonal Somvanshi et al.There is no large study from North India which has addressed association of (CAD) in angiographically proven cases with lipid levels and the conventional risk factors. In the present study risk factor assessment was done in 200 consecutive patients admitted for coronary angiography and in 200 age and sex matched controls. We have found that the most important predictor of … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 1 · 31 Mar 2006 · 7,051 accessesView PDFCite