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25 results for “Cytotoxic Activity”
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Research ArticleOpen accessPhrase in the titleStudy of Chemical Composition of Extract from Beta Vulgaris Seeds and its Cytotoxic ActivityAiman Konkabayeva, Margarita Ishmuratova, Gulmira Tykezhanova et al.Nowadays, a variety of plants is being investigated with the aim of developing new medicines with improved properties and expanding the range of efficient and safe preparations. Modern studies of representatives of the family Amaranthaceae (Beta vulgaris) have revealed medicinal properties in plants that were used previously only as food. Many medicinal properties are due to the presence of betalains … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 27 May 2021 · 6,220 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleChemical Composition of Propolis from Different Regions in Java and their Cytotoxic ActivitySyamsudin, Sudjaswadi Wiryowidagdo, Partomuan Simanjuntak, Wan Lelly HeffenProblem statement: Propolis samples from tropical zones, such as Java (Indonesia) with its vast biodiversity, have become a subject of increasing scientific and economic attention. The association of the chemical composition of propolis from different geographic regions with cytotoxic activities lead to the identification of active principles, a fundamental tool to achieve standardization of this bee product. Approach: The purpose … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 4 · 31 Dec 2009 · 8,269 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleCytotoxic Activity of Tinospora crispa Crude Extracts (Stem) Against K562 Human Leukemia CellsNormah Awang, Haziratul Iffah Ruzali, Rapidah Mohamad et al.Tinospora crispa (T. crispa) is traditionally used as an herbal medicine for treatment of gout and is an analgesic, anti-inflammatory and antihyperuricemic agent. Cytotoxicity of hexane, dichloromethane, ethanol and aqueous extracts of T. crispa stem against K562 cells was assessed. Crude extracts of T. crispa stem were obtained by sonication and maceration methods. T. crispa stem powder was macerated and … …OnLine Journal of Biological Sciences, Vol. 19, Issue 2 · 11 May 2019 · 7,870 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleRETRACTED: Evaluation of the Cytotoxic Activity of Aqueous Extract of Schinus terebinthifolius RaddiA. Arnóbio, O. N. Terra Jr., P. R.G. Lemos et al.Phytotherapy consists in all pharmaceutical preparation using certain part of plants as a feedstock with known pharmacological effects for medicinal purposes. In order to a better understanding of the biological effects associated with herbal medicines, many scientific studies have been conducted and developed in recent years. SchinusterebinthifoliusRaddi (Aroeira) is native from Peru and is also found in Europe, Asia and … …American Journal of Infectious Diseases, Vol. 8, Issue 4 · 8 Feb 2013 · 7,611 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPharmacological Properties of Bioactive Extracts from the Rhizome of Aristolochia longa LAmal El Hamsas El Youbi, Dalila BoustaAristolochia longa is a medicinal plant well known in Moroccan folk medicine for its activity against constipation, intestinal infections and skin diseases. The present study was performed to evaluate in vitro and in vivo immunomodulatory and cytotoxic activities of aqueous and protein extracts of A. longa. The in vitro immunomodulatory results showed that aqueous extract at 0.1 mg/mL enhanced T-lymphocyte … …American Journal of Pharmacology and Toxicology, Vol. 15, Issue 1 · 21 Jul 2020 · 7,456 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSynthesis and Biological Evaluation of 6-Hydroxy-4-Methyl-5,7-(Bis-p-ChlorophenylAzo) CoumarinDalal M. Ibrahim, Juliana Jumal, Farah Wahida Harun6-hydroxy-4-methyl-5,7-(bis-p-chlorophenylazo)coumarinhas been synthesized and characterizedby CHN elemental analysis, FTIR, 1H-NMR-spectroscopy andmass-spectral data. Cytotoxic screening by MTT assay was carried out on the compoundagainst breast cancer cells. The overall results from preliminary screeningprogram revealed that the cell proliferation was highly inhibited by 6-hydroxy-4-methyl-5,7-(bis-p-chlorophenylazo)coumarin with the value of 2.81%, at concentration of 30 µg mL-1 comparedwith the untreated control cells and also … …American Journal of Applied Sciences, Vol. 13, Issue 1 · 21 Dec 2015 · 7,670 accessesView PDFCite
Short CommunicationsOpen accessIn the abstractCytotoxicity and Apoptosis-Induction Potential of Fraction F3 from Fruits of Bersama engleriana (Melanthaceae) against Human Cervical Cancer CellsMichèle Stella Majoumouo et al.Cervical cancer is one of the most life-threatening malignancies worldwide, despite intensive research for more efficacious chemotherapeutic agents. Recent efforts geared towards eradicating the scourge of cancer have embodied a major surge of interest in natural products as promising lead molecules in pharmaceutical development and therapeutic translation. Consequently, this study aimed to assess the cytotoxicity of a previously identified plant … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 5 Dec 2022 · 5,292 accessesView PDFCite
Research ArticleOpen accessIn the abstractCrude Extract of Blue-Green Pigment Derived from the Marine Bacterium Pseudomonas aeruginosa P1.S9 has Antibacterial, Antioxidant, and Cytotoxic ActivitiesAris Tri Wahyudi, Rahmah Nursari, Widya Esti Purwaningtyas et al.Pigment derived from marine bacteria is one of the alternative sources of natural products characterized by beneficial functions for pharmaceutical purposes. This study aimed to evaluate the antimicrobial, antioxidant and cytotoxic activities of the marine bacterium Pseudomonas aeruginosa P1. S9 crude pigment extract and identify its chemical content. Crude pigment extract of this bacterium showed promising antibacterial activities against Pseudomonas … …OnLine Journal of Biological Sciences, Vol. 22, Issue 1 · 4 Mar 2022 · 6,994 accessesView PDFCite
Research ArticleOpen accessIn the abstractSelective Susceptibility of Human Bladder Transitional Cell Carcinoma T24 Cells towards NBD PeptideSankari Durairajan, Charles Emmanuel Jebaraj Walter, Kalaiselvi Periyandavan et al.Bladder cancer is a recurrent disease that often develops chemoresistance and is on the rise in developing countries. After diagnosis surgery followed by immunotherapy and/or chemo- radiation therapy are the available treatments. These treatments do not provide protection against disease progression or recurrence thus highlighting the need to identify and develop drugs that are capable of inhibiting bladder cancer. T24 … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 20 Apr 2020 · 7,787 accessesView PDFCite
Research ArticleOpen accessIn the abstractLarvicidal Activity of Bruceine A against Aedes aegypti and Toxicity on Vero CellsDwi Sutiningsih, Mustofa, Tri Baskoro Tunggul Satoto, Edhi MartonoVector control is still based on the use of chemical insecticides, which can cause death of nontarget animals, pollution and the emergence of vector resistance. This study aims to assess the larvicidal activity of bruceine A against larvae of Aedes aegypti and its cytotoxic activity against Vero cells. Extraction and isolation of bruceine A from the seeds of Brucea javanica … …OnLine Journal of Biological Sciences, Vol. 18, Issue 3 · 4 Sep 2018 · 7,912 accessesView PDFCite