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Research ArticleOpen accessEvery word in the titleCytotoxicity and Apoptosis Prevailed by Tricyclohexyltin(IV) Dithiocarbamate Compounds Against Human Lung Carcinoma Cell Line (A549)Normah Awang, Nurul Amalina Abd Aziz, Nur Fatini Nordin, Nurul Farahana KamaludinIn Malaysia, lung cancer is a highly common kind of cancer and the leading cause of cancer-related deaths. This study examined the cytotoxicity of two new tricyclohexyltin(IV) dithiocarbamate compounds compounds, which are tricyclohexyltin(IV) N-methyl-N-benzyldithiocarbamate (C1) and tricyclohexyltin(IV) N-ethyl-N-benzyldithiocarbamate (C2), on lung carcinoma cell lines (A549) of humans. The cytotoxicity was assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) assay. Cell death mode … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 13 Jun 2024 · 4,622 accessesView PDFCite
Literature ReviewOpen accessEvery word in the titleThe Benefits of Selected Nutritional Compounds Towards Atherosclerosis ManagementAnastasia Vladimirovna Poznyak, Mariam Bagheri Ekta, Vasily Nikolaevich Sukhorukov et al.Globally, the prevalence of obesity, type 2 diabetes, and metabolic syndrome is steadily rising, potentially giving rise to the most extensive non-communicable health crisis ever recorded blocking the flow are able to break and cause a blood clot. The possible consequence is a significant increase in atherosclerotic cardiovascular disease rate. The atherosclerotic cardiovascular disease largely depends on modifiable factors, however, … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 2 Nov 2023 · 5,032 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleQSAR Modeling of Thirty Active Compounds for the Inhibition of the Acetylcholinesterase EnzymeNour El Houda Hammoudi, Yacine Benguerba, Widad SobhiThis work aims at developing a reliable and predictive QSAR model which allows, on one hand, an exploration of the main molecular descriptors responsible for the inhibitory activity towards the Acetylcholinesterase enzyme and, on the other hand, predict the inhibitory activity of new compounds before testing them experimentally. This study involves a series of DL0410 and its 29 DL0410 derivatives. … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 2 Mar 2020 · 11,426 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMolecular Docking of New Active Compounds Towards the Acetylcholinesterase EnzymeLemaoui Tarek, Hammoudi Nour El Houda, Benguerba Yacine, Attoui AyoubMolecular docking is a key instrument in structural molecular biology and computer-assisted drug design. The objective of ligand-protein docking is to expect the main binding mode(s) of a ligand with a protein of known three-dimensional structure. Effective docking methods search high-dimensional spaces effectively and finding a scoring function that correctly ranks candidate dockings (Morris et al., 2008). In this study … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 27 Feb 2020 · 11,404 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleChemical Coagulation/Flocculation Processes for Removal of Phenolic Compounds from Olive Mill Wastewater: A Comprehensive ReviewMounia Achak, Fatima Elayadi, Wafaa BoumyaOlive oil extraction processes generate three phases: Olive oil, solid residue (pomace) and aqueous liquor Olive Mill Wastewater (OMW). OMW causes serious environmental deteriorations such as coloring of natural waters, alteration of soil quality, phytotoxicity and odor nuisance. The direct discharge of this effluent into the soil bring various negative effects on the environment, due to its high load of … …American Journal of Applied Sciences, Vol. 16, Issue 3 · 30 Mar 2019 · 10,494 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleBioactive Compounds from Sponge Associated Bacteria: Anticancer Activity and NRPS-PKS Gene Expression in Different Carbon SourcesJepri Agung Priyanto, Rika Indri Astuti, Jun Nomura, Aris Tri WahyudiSponge associated bacteria with diverse NRPS-PKS genes could be the alternative source of bioactive compounds. This study aimed to analyze the activity as well as the regulatory mechanism regarding the anticancer properties derived from these bacteria against cancer cell lines. Extraction of bacterial metabolites using ethyl acetate solvent resulted yield ranging from 0.003 to 0.016% (w/v). Six extracts of bacterial … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 5 Oct 2017 · 8,886 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleINDUCES OF ANTIOXIDANT COMPOUNDS AND SALT TOLERANCE IN WHEAT PLANT, IRRIGATED WITH SEAWATER AS RESPONSE TO APPLICATION OF MICROALGAE SPRAYHanaa H. Abd El Baky, M. M. Hussein, Gamal S. El-BarotyWheat plants (Triticum aestivum L., cv. Giza 168) irrigated with either 10 or 20% of Seawater (SW) were treated with aqueous extracts of green microalgae Scenedesmus obliquus and blue green algae Spirulina platensis (AESO and AESP 20 g (dry weight)/L) in order to increase wheat salt tolerance. Treated plants showed higher ability to tolerate salt stress (10 or 20% SW) … …American Journal of Agricultural and Biological Sciences, Vol. 9, Issue 2 · 7 Jan 2014 · 7,591 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleTHE GROUP COMPOSITION OF METAL COMPOUNDS IN SOIL AS AN INDEX OF SOIL ECOLOGICAL STATESaglara Sergeevna Mandzhieva, Tatiana Mikhailovna Minkina, Svetlana Nikolaevna Sushkova et al.A system of indices for assessing the soil ecological state as based upon the group composition of heavy metal compounds in soils is proposed. The group composition of heavy metal were determined using combined fractionation including sequential and parallel extractions (1 N NH4Ac, pH 8; 1% EDTA in NH4Ac and 1 N HCl). It was shown that strongly bound compounds … …American Journal of Agricultural and Biological Sciences, Vol. 9, Issue 1 · 7 Dec 2013 · 7,593 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAntidiarrheal Activity of Apus Bamboo (Gigantochloa apus) Leaf Extract and its Bioactive CompoundsNoryawati Mulyono, Bibiana Widiyati Lay, Laora Ocktreya, Sri RahayuMost of every part of bamboo plants had economical value. The wood is used as building and furniture, the shoot is processed as health foods and medicines, the root and culms are used as traditional medicine. The leaf has been believed that it could heal diarrhea in piglets, rabbit, poultry and calves. This research was designed to investigate the inhibition … …Current Research in Microbiology, Vol. 4, Issue 1 · 19 Jan 2013 · 9,590 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAntibiotic Compounds from Bacillus: Why are they so Amazing?Patrick FickersThe constant increase of multi-drug resistant pathogens stimulates research, more than ever, to identify and develop new antibacterial compounds. The recent advances in genome sequencing have highlighted the genus Bacillus as an unexpected source of antibiotic-like compounds. This review focus on the different class of antimicrobial molecules produce by Bacillus genus such as polyketides, nonribosomal peptide, bacteriocins as well as … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 1 · 15 Mar 2012 · 9,684 accessesView PDFCite