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410 results for “Cancer”
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Research ArticleOpen accessEvery word in the titleIsolation and Identification of Oral Cancer Stem Cells (CSC) within Commercially Available Cell LinesRobert Chauncey, Kai Hatch, Toni Jilka et al.Previous studies have demonstrated some tumors develop or maintain a small sub-population of cells with stem cell-like properties. This Cancer Stem Cells (CSC) may exhibit differential properties that allow their escape from traditional radiation or chemotherapy treatments and may therefore be responsible for cancer recurrence. Few studies have explored this phenomenon among oral cancer cell lines, therefore the objective of … …Current Research in Dentistry, Vol. 9, Issue 1 · 2 Jun 2018 · 12,719 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSpousal Interaction and Breast Cancer Screening Among Korean AmericansUsha Menon, Eunice Lee, Jennifer Kue et al.Breast cancer screening rates for Korean Americans (KA) are low, leading to higher morbidity and mortality of the screening interventions tested, almost none account for family interactions and communication between KA couples. The purpose of this study was to explore communication patterns between KA wives and husbands about breast cancer screening after attending an educational program on breast health. Couples … …International Journal of Research in Nursing, Vol. 9, Issue 1 · 30 Mar 2018 · 7,240 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMolecular Analysis of KRAS Mutation Associated with Colorectal Cancer in Iraqi PatientsRehab Subhi Ramadhan, Aola Sabah Ali, Rebah Najah AlgafariThe role of KRAS gene was investigated in manifestation of colorectal cancer in Iraqi patients. A total 40 blood samples were collected during October 2016 to January 2017 from AL-Amal Hospital in Baghdad and 20 blood samples from healthy subjects served as control. Blood samples were collected from subjects of 40-70 years old for both patients and control. The study … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 1 · 3 Mar 2018 · 9,024 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleRelative Transcription Expression Level of SIRT1, SIRT2 and SIRT3 in Correlation to the Expression of a Set of Selected Cancer Related Genes in Human Breast CancerHamdy Swelim, Omnia Mansour, Salah Abdel-Rahman et al.Mammalian Sirtuins have been shown to perform distinct cellular functions and deregulated expression of these genes was reported to be involved in the development of various malignancies including breast cancer. An increasing number of evidence indicates that Sirtuins have both tumor promoter and tumor suppressor functions. However, the roles of Sirtuins have not been well-studied in breast cancer. In the … …OnLine Journal of Biological Sciences, Vol. 18, Issue 2 · 18 Jan 2018 · 7,476 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Implementation of Online Learning for Early Detection of Cervical CancerHery Harjono Muljo, Bens Pardamean, Anzaludin Samsinga PerbangsaCervical cancer is the second leading type of cancer causing death among women in Indonesia. The mortality rate caused by cervical cancer could be reduced through an early detection program, which would require the training of healthcare workers in educating women in Indonesia. The aim of this study was to develop an online learning management system prototype that is suitable … …Journal of Computer Science, Vol. 13, Issue 11 · 9 Nov 2017 · 7,566 accessesView PDFCite
EditorialOpen accessEvery word in the titleKetogenic Diet and Immunotherapy in Cancer and Neurological Diseases. 4th International Congress on Integrative Medicine, 1, 2 April 2017, Fulda, GermanyThomas Peter, Marco RuggieroIn this Meeting Report, we review proceedings and comment on talks given at the 4th International Congress on Integrative Medicine held on April 1 and 2, 2017, in Fulda, Germany. The Theme this year was “Ketogenic Diet and Immunotherapy in Cancer and Neurological Diseases.” Speakers came from Europe and the United States and the Congress was attended by more than … …American Journal of Immunology, Vol. 13, Issue 3 · 25 Sep 2017 · 8,866 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleStudying Interrelation of PDLIM4 with the Model of CD74-Mediated Development of Breast CancerDmitry Sergeevich Kravchenko, Yuriy Nikolaevich Lezhnin, Anna Evgenyevna Ivanova et al.Mammary gland tumors are often characterized by deregulation of RIL/PDLIM4 expression, however, PDLIM4-mediated mechanisms of cancer development still remain unknown. The aim of our research was to study the influence of PDLIM4-deregulation on transcript me changes of malignized cells. We performed а comparative NGS-analysis of breast cancer cell lines with suppressed and induced expression of PDLIM4 and identified a number … …OnLine Journal of Biological Sciences, Vol. 17, Issue 2 · 3 Jun 2017 · 7,419 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA Bayesian Adaptive Design for Combination of Three Drugs in Cancer Phase I Clinical TrialsMourad Tighiouart, Quanlin Li, Steven Piantadosi, Andre RogatkoWe describe a Bayesian adaptive design for early phase cancer trials of a combination of three agents. This is an extension of an earlier work by the authors by allowing all three agents to vary during the trial and by assigning different drug combinations to cohorts of three patients. The primary objective is to estimate the Maximum Tolerated Dose (MTD) … …Current Research in Biostatistics, Vol. 6, Issue 1 · 25 Aug 2016 · 8,421 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleHypermethylation and Hypomethylation of DNA: Implication for Diagnosis and Prognosis of Prostate CancerLubos Danisovic, Stanislav ZiaranProstate cancer belongs to the most common cancers and it is the second leading cause of cancer death in men. A genetic predisposition with epigenetic changes in DNA contributes to the development of the disease. DNA hypermethylation and hypomethylation belong to the most studied epigenetic changes in prostate cancer development. Both forms may lead to chromosomal instability and transcriptional gene … …OnLine Journal of Biological Sciences, Vol. 15, Issue 2 · 13 Jun 2015 · 6,528 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCrosstalk between Oxidative Stress Signaling and HER2 Pathway in Breast CancerVanessa Jacob Victorino, Adriano Martin Felis Aranome, Fernanda Carolina de Campos et al.About 20% of breast cancer patients overexpress the Human Epidermal growth factor Receptor-2 (HER2), also known as ErbB2. HER2-overexpression is associated with enhanced tumor malignancy and its overexpression is related to specific target therapy against breast tumors and other cancers. HER2-mediated pathways in tumor cells act on behalf of the tumor conferring aggressive characteristics. Several reports demonstrated the occurrence of … …American Journal of Immunology, Vol. 10, Issue 4 · 17 Jan 2015 · 8,038 accessesView PDFCite