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46 articles for “Genetic Mechanism”
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Review ArticleOpen accessIn the abstractResveratrol for Atherosclerosis: Potential MechanismsAnastasia Vladimirovna Poznyak, Sergey Kozlov, Gulalek A Babayeva et al.Cardiovascular disease is a big problem around the world. At the heart of most serious cardiovascular diseases is such a pathology as atherosclerosis. Atherosclerosis is a complex set of interactions between inflammation, oxidative stress, lipid disorders, and other molecular, genetic, and lifestyle factors. It is this complexity and multicomponent nature of atherogenesis that make the treatment of atherosclerosis a non-trivial … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 11 Aug 2026 · 605 accessesView PDFCite
Research ArticleOpen accessIn the abstractEpigenetic Regulation of Extracellular Matrix Remodeling in Skin Aging: Mechanisms and InteractionsJiguang Yang, Yusong Shi, Xiaoqing YanSkin aging results from complex interactions between genetic factors, environmental stressors, and epigenetic modifications that regulate extracellular matrix (ECM) remodeling. Accumulation of senescent cells impairs tissue regeneration through mechanisms including telomere shortening, reactive oxygen species accumulation, and ultraviolet (UV) radiation exposure. While epigenetic pathways regulate skin homeostasis, regeneration, and senescence, the specific epigenetic changes occurring during UV exposure, chronological aging, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,458 accessesView PDFCite
Research ArticleOpen accessIn the abstractOPTIMAL RESOURCE ALLOCATION FOR LAYERED VIDEO MULTICASTING IN WIMAXHung-Yi Teng, Chun-Hung Wu, Ren-Hung HwangReal-time video disseminations over wireless links such as video telephony, video conferencing and mobile TV have become fast growing applications. In order to cope with the increasing users' demand, a new scalable and efficient wireless distribution platform is needed. With numerous advantages such as QoS assurance, high data rate and wide coverage, WiMAX has been regarded as an ideal choice … …Journal of Computer Science, Vol. 10, Issue 12 · 24 Dec 2014 · 7,410 accessesView PDFCite
Research ArticleOpen accessIn the abstractMicrornas as Double Edged Sword in CancerBaby Joseph, Vrundha M. NairCancer is the leading causes of death world wide. Basically it can be defined as the disease of the cell. One among the mechanism of transfer of a normal cell to cancerous is the alteration in the genetic material DNA. Treatment for cancer remains as a biggest challenge. Here comes the importance of miRNAs. They are endogenous RNA which regulates … …Current Research in Bioinformatics, Vol. 2, Issue 1 · 24 May 2013 · 6,953 accessesView PDFCite
Research ArticleOpen accessIn the abstractAgro-Process Intensification through Synthetic Rhizosphere Media for Nitrogen Fixation and Yield Enhancement in PlantsG. Akay, D. R. BurkeProblem statement: In order to combat global warming and the emerging Food, Energy and Water shortages (FEWs), several approaches have been adopted, including genetic engineering and farming practices. Biomass based energy technology will further stress food and water resources and hence novel holistic approaches to FEWs should be designed. Approach: A novel technique (Agro-Process Intensification, A-PI) which simultaneously addresses FEWs … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 2 · 15 Mar 2012 · 8,599 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Mechanisms for Altered Glucose Homeostasis in HIV InfectionPaula W. HruzA complete understanding of the molecular mechanisms leading to HIV-associated insulin resistance remains elusive. Complex interrelationships between genetic predisposition, disease-related body changes and multidrug therapy all contribute to alterations in glucose homeostasis. These abnormalities can be differentiated between acute and reversible changes directly induced by HAART medications and more chronic and less reversible changes due to the development of lipodystrophy … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,877 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Seasonal Temperature on the Genotypic Variability of Flowering Duration in Pearl Millet (Pennisetum glaucum) in NigerSani Daouda Ousmane, Mouhamadou Mounkaila Boureima, Maman Nassourou Lawali et al.Heat stress is a major contributor to crop losses worldwide. Millet [Pennisetum glaucum (L.) R. Br.] is a staple crop for inhabitants of arid and semi-arid regions of the world, due to its extraordinary adaptation to drought and high temperatures. Climate change points to an overall increase in temperature, the effect of which on crop growth and productivity remains to … …American Journal of Agricultural and Biological Sciences, Vol. 17, Issue 1 · 30 Nov 2022 · 6,125 accessesView PDFCite
Research ArticleOpen accessIn the abstractColor Doppler Evaluation of Isovolumetric Relaxation Time and of Signals Arising from Axons of the Median Nerve as a Means to Evaluate Mitochondrial Functionality in the Context of Immunotherapy of Cancer and Chronic Conditions Associated with Mitochondrial DysfunctionStefania Pacini, Marco RuggieroReactive Oxygen Species (ROS) arising from the disruption of mitochondrial respiration act as endogenous mutagens and tumor promoters. When production of ROS exceeds the capacity of DNA repair mechanisms, random mutations and aneuploidy ensue, thousands of genes become unbalanced and genetic/epigenetic chain reactions lead to progressive aneuploidy with only two outcomes: karyotypes so altered that are not viable or karyotypes … …American Journal of Immunology, Vol. 15, Issue 1 · 12 Oct 2019 · 9,690 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Triple Immune Argument; Surveillance/Evasion/ Senescence and the Increased Incidence of Acute Myeloid Leukemia Observed with AgeManar M. IsmailAML originates from genetic insults of hematopoietic stem and progenitor cells (HSPCs/HSCs) that was identified earlier as leukemia stem cells (LSCs). In quiescent state, trafficking immune cells are crucial for eradication of aberrant clones and obtaining balance between proliferation and apoptosis to maintain HSCs pool. Regulatory T-cells shield the HSCs from the inflammatory reactions by suppressing T- and B- cells. … …American Journal of Immunology, Vol. 13, Issue 4 · 22 Dec 2017 · 7,806 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrevalence of miRNAs in Introns and Cis-Regulatory Regions of Genes of the Somatotropic Axis in MammalsTatiana Shkurat, Dmitry Romanov, Evgeny Pshenichnyy et al.To understand the role of microRNA in genetic control of animal growth mechanisms, we performed bioinformatic analysis of the localization of microRNAs in introns and cis-regulatory regions of the somatotropic axis genes-GH1, GHRH, SST and IGF1 in Homo sapiens, Macaca mulatta, Pan troglodytes, Pongo abelii, Gorilla gorilla, Ovis aries, Bos Taurus, Loxodonta Africana, Oryctolagus cuniculus, Canis lupus, Rattus norvegicus and … …American Journal of Applied Sciences, Vol. 12, Issue 1 · 26 Jan 2015 · 7,015 accessesView PDFCite