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52 articles for “chemotherapy”
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Research ArticleOpen accessIn the keywordsPatterns of Resection among Patients with Hepatic-Only Metastatic Colorectal Cancer a Single Institution Experience and ReviewK.I. Quintyne, N. O’Leary, O. O’Kelly et al.Problem statement: Hepatic-only metastasis in colorectal cancer is not a rare clinical finding and can account for 30% of cases. However, only 10-25% of cases are suitable for hepatic resection as part of their treatment pathway. We sought to document our own findings by reviewing patients with hepatic-only disease. Approach: A retrospective analysis was designed to include all patients seen … …American Journal of Immunology, Vol. 8, Issue 1 · 5 Apr 2012 · 7,196 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffect of Triclabendazole and Levamisole on Experimental Hydatic Cyst in RatGaredaghi Yagoob, Khayatnouri Mirhadi, Sadeghi Peyman, Safarmashaei SaeidProblem statement: Hydatidosis has dispersed worldly and is one of the common dangerous diseases between human and animals and is found abundantly in areas that human, dogs and herbivorous are in close relationship. Approach: In this study, firstly, 32 rats were divided into two groups of control and case and 2000 protoscolices were injected into peritoneal hole. After two months, … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 2 · 8 Aug 2011 · 8,043 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA 30 Year Old Man with Fever and Indolent Soft Tissue MassesWissam Zaeeter, Ashwin Jathavedam, Rosalyn StahlAbstract: Problem statement: Multifocal Skeletal Tuberculosis (MSTB) is a rare presentation of skeletal tuberculosis. The indolent nature of this condition often leads to delayed or missed diagnosis, sometimes with devastating consequences for the patient. In order to provide meaningful clinical information and to highlight pitfalls in diagnosis of MFST, we present a case of MSTB. A review of this condition … …American Journal of Infectious Diseases, Vol. 6, Issue 3 · 30 Sep 2010 · 7,713 accessesView PDFCite
Research ArticleOpen accessIn the abstractQuantitative Analysis of Hypothalamic Proline-Rich Peptide-1 in Blood Serum of Patients with Malignant TumorsNarine Tumasyan, Silva Abrahamyan, Nune Kocharyan et al.The proline-rich-peptides are a class of neurosecretory hypothalamic bioactive polypeptides derived from cattle and comprise the content of bovine posterior pituitary neurosecretory granules. These peptides are co-validated through a single precursor protein neurophysin-vasopressin-associated glycoprotein. Proline-Rich-Polypeptide-1 (PRP-1) is a 15-amino acid peptide with anti-neurodegenerative, immunoregulatory, hematopoietic, antimicrobial, and antitumor activity. The aim of this study, accordingly, is to elaborate an assay … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 27 Nov 2025 · 2,283 accessesView PDFCite
Research ArticleOpen accessIn the abstractMechanism Analysis of Artemisinin and Artesunate as Lung Cancer Therapy Agents Through in Silico MethodDidik Harmoko, Vivitri Dewi Prasasty, Adi YulandiSeveral in vitro studies have focused on the ability of artemisinin and its derivatives to suppress lung cancer cells, but there are still many biological processes and mechanisms, such as the interactions between the active compounds (ligands) and receptors that are not well understood and require further research. Drug targeting for lung cancer will be more precise and the inhibition … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 15 Feb 2024 · 6,144 accessesView PDFCite
Research ArticleOpen accessIn the abstractUse of Novel Triphenyltin (IV) Dithiocarbamate Compounds in Assessing the Cytotoxicity and Mode of Cell Death of Acute Lymphoblastic Leukemia Cell Lines, CCRF CEM (CCL-119)Normah Awang, Nur Hidayah Hasrin, Nurul Farahana Kamaludin et al.Chemotherapy and radiotherapy are often used to treat Acute Lymphoblastic Leukemia (ALL). However, the resistance problem of treatment using the current drug in ALL patients has decreased the effectiveness of such therapy. Therefore, a study needs to be conducted to identify the potential of new anticancer agents. Organotin (IV) dithiocarbamate, an organometallic compound, causes toxic effects on cancer cells in … …OnLine Journal of Biological Sciences, Vol. 23, Issue 2 · 10 Mar 2023 · 5,159 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Vitamin B17 Against Growth of Colitis Bearing Mice Induced Variations in Colon Structure, AFP, CEA and PCNA ImmunoreactivityGihan Hosny Abd Elsamie, Sabah Gaber El-Banna, Ehab Tousson et al.Colitis alludes to inflammation of the internal coating of the colon that accompanied clinically through abdominal pains, diarrhea, weight loss, nausea. Current study aimed to study the impact of vitamin B17 against growth of colitis bearing mice induced variations in colon structure, AFP, CEA and PCNA immune reactivity. Forty female Swiss albino mice separated into 4 groups (Control, vitamin B17, … …OnLine Journal of Biological Sciences, Vol. 21, Issue 3 · 23 Aug 2021 · 6,397 accessesView PDFCite
Research ArticleOpen accessIn the abstractSelective Susceptibility of Human Bladder Transitional Cell Carcinoma T24 Cells towards NBD PeptideSankari Durairajan, Charles Emmanuel Jebaraj Walter, Kalaiselvi Periyandavan et al.Bladder cancer is a recurrent disease that often develops chemoresistance and is on the rise in developing countries. After diagnosis surgery followed by immunotherapy and/or chemo- radiation therapy are the available treatments. These treatments do not provide protection against disease progression or recurrence thus highlighting the need to identify and develop drugs that are capable of inhibiting bladder cancer. T24 … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 20 Apr 2020 · 7,787 accessesView PDFCite
Research ArticleOpen accessIn the abstractClinical Analysis of Pulmonary Mycobacterium kansasii DiseaseYoshihiro Kobashi, Masaaki Abe, Daisuke Yoshioka et al.To investigate the clinical aspects of pulmonary Mycobacterium kansasii (M. kansasii) disease. In 25 patients who satisfied the diagnostic criteria of the American Thoracic Society, we retrospectively evaluated the background, diagnostic methods, laboratory findings, radiological findings, treatment and prognosis. The median age was 61 years old (20 males, 5 females). Nine patients (36%) had no underlying diseases. The definite diagnosis … …American Journal of Infectious Diseases, Vol. 16, Issue 1 · 21 Jan 2020 · 7,111 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenetic Mutation Assessment of NPM1 Gene and Gene Expression of MDR1 in Iraqi Patients with Acute Myeloid LeukemiaAhmed Abduljabbar Suleiman, Ali Zaid Al-Saffar, Tamadher Abbas Rafaa, Hasan Abdulwahab JwadSince its discovery, mutations in NPM1 have been frequently associated with a large number of Acute Myeloid Leukemia (AML) patients. The vast majority of genetic changes were previously detected in exon 12, however little information report mutations in Nuclear Export Signal region (NES) of NPM1. Sequencing analysis included exon 2 and 3 for 75 Iraqi AML patients showed three SNPs, … …OnLine Journal of Biological Sciences, Vol. 18, Issue 1 · 11 Jan 2018 · 7,782 accessesView PDFCite