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53 results for “chemotherapy”
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Research ArticleOpen accessEvery word in the titleFrom Humans to Dogs and Back: The Translational Lesson of Metronomic ChemotherapyAlessio Pierini, Guido Bocci, Mario Giorgi et al.The main priority in veterinary oncology is to maintain patient quality of life. It is important that new chemotherapy strategies aim to minimize side effects, thus making the treatment attractive for owners as well as their pets. Metronomic chemotherapy has been shown to have an important stabilizing effect on human cancer (including chemotherapy-resistant disease) resulting in prolonged clinical benefit. In … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 4 · 31 Dec 2012 · 7,738 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCancer Chemotherapy and Immune RegulationJohn Barrett, Katarina Le BlancProblem statement: Chemotherapeutic drugs have been used to treat malignancy for over 50 years, but the potential of cytotoxic agents to suppress immunity and interfere with Immunosurveillance (IS) of cancer has been largely ignored. Assuming that the immune control of the cancer had a priori already failed, the effect was not considered to have a major impact on treatment outcome. … …American Journal of Immunology, Vol. 5, Issue 1 · 31 Mar 2009 · 40,663 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImpact of CTLA-4 Inhibitor Combined with Chemotherapy on Immunoglobulin Levels and General Condition in Breast Cancer PatientsRuiguang CaiThis study conducted an evaluation of the CTLA-4 inhibitor ipilimumab plus standard chemotherapy on immunoglobulin levels, performance status, and Quality of Life (QoL) in patients with stage I-III Breast Cancer (BC) via a randomized controlled trial. 120 patients with stage I-III BC were randomly allocated to the experimental group (chemotherapy + ipilimumab) and the control group (chemotherapy), and the treatment … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 3 Jul 2026 · 1,115 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDifferential Expression of Cellular and Exosomal MicroRNA Isolated from Oral Cancer Cells and their Resistance to ChemotherapyBrady Petersen, Carl Yu, Samuel Hutchings et al.MicroRNAs are abundant small non-coding RNA with a variety of known functions, including transcriptional activation and inhibition. Recent evidence has suggested that microRNA expression may influence the responsiveness of some cancers to chemotherapy, including liver and lung cancers. Some evidence has now suggested that specific microRNAs, such as miR-21, miR-155, and miR-375, may influence oral cancer responsiveness to chemotherapy – … …Current Research in Dentistry, Vol. 13, Issue 1 · 29 Jul 2022 · 5,902 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleClinical Significance of Precise Hyperthermic Intraperitoneal Chemotherapy Up-regulation RP11-356I2.2 Restraining the Occurrence and Development of Gastric CancerYu Yan, Feng Yanlin, Feng Jinxin et al.In order to study the therapeutic effect and possible mechanism of Precise Hyperthermic Intraperitoneal Chemotherapy (HIPEC) on gastric cancer, the expression of RP11-356I2.2 in gastric cancer cell lines and tissues was detected by real-time fluorescence quantitative PCR (RT-PCR). Chi-square test was used to analyze the correlation between the expression and clinic pathological parameters. Western blotting was used to detect the … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 4 Jun 2020 · 6,487 accessesView PDFCite
Research ArticleOpen accessIn the keywordsNursing Management of Frail Patients with Hematologic Malignancies During COVID-19 Pandemia in the Viterbo Domiciliary Care Unit: Data Analysis from March 2020 to March 2021Silvia Ciambella, Vincenza Innocenti, Elisa Emanueli Cippitelli et al.Background In the Viterbo province, a Domiciliary Hematologic Care Unit (DHCU) for assistance to frail patients (pts) with hemopathies Methods To evaluate the role of nursing management for frail pts followed by DHCU during the first year of the COVID-19 pandemia, all nursing activities from 3/2020 to 3/2021 were analyzed. Results Overall, 107 pts in 43 municipalities of Viterbo province … …International Journal of Research in Nursing, Vol. 15, Issue 1 · 26 Feb 2024 · 8,829 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEfficiency of Carica papaya L. Seeds in Anticoccidial Control for Cockerel of Lohmann Brown StrainKomlan Mawouli Wampah, Kosi Mawuéna Novidzro, Namponi Dianam, Abalo Essosimna KuloTo combat avian coccidiosis, chemical products are widely used in poultry farming. However, chemotherapy has inconveniences due to the bioresistance of Coccidia and the presence of undesirable residues in consumer products. The aim of this study is to investigate the toxicity of papaya seeds as a bio-insecticide against Coccidia in Lohmann brown chickens in order to improve their zootechnical parameters. … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 1 · 27 Jan 2024 · 6,659 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPrevalence of Paragonimus InfectionNworie Okoro, Reginald Azu Onyeagba, Chukwudi Anyim et al.Paragonimiasis (human infections with the lung fluke Paragonimus westermani) is an important public health problem in parts of Africa. This study was aimed at assessing the prevalence of Paragonimus infection in Ebonyi State. Deep sputum samples from 3600 individuals and stool samples from 900 individuals in nine Local Government Areas in Ebonyi State, Nigeria were examined for Paragonimus ova using … …American Journal of Infectious Diseases, Vol. 9, Issue 1 · 2 Mar 2013 · 7,810 accessesView PDFCite
Research ArticleOpen accessIn the keywordsRelationship Between Blood Fibrinogen Concentration and Pathological Features of Cancer Patients: A 139-case Clinical StudyDa-Yong Lu, Xue-Liang Chen, Min Huang et al.Angiogenesis and coagulation are among the most consistent host responses to the presence of a malignant tissue. Pathological angiogenesis and coagulation are often occurred in patients with solid tumors, especially in the occurrence of neoplasm metastasis and as targets for anti-metastatic drugs such as antiangiogenesis agents, coagulation-mediated agents and anticancer drugs. Since fibrinogen (Fib) is the most abundant and key … …OnLine Journal of Biological Sciences, Vol. 7, Issue 1 · 4 Sep 2010 · 7,859 accessesView PDFCite
Research ArticleOpen accessIn the keywordsβ1,3-GLUCAN ANTICANCER EFFICACIES AND SYNERGIES: A REVIEWStory Jenny, Vetvicka Vaclav, Angove Michaelβ1,3-glucans from fungi, cereals, seaweeds and bacteria have been shown to possess favourable biological and anti-carcinogenic activities including upregulation of phagocytosis, cytokine production enhancement, superoxide and nitrite production; antibody secretion and stimulation of signalling pathways associated with proto-oncogene expression. However, human dietary supplements containing β1,3-glucans vary in efficacy due to glucan source, the lifecycle stage of the source at extraction, … …American Journal of Immunology, Vol. 10, Issue 3 · 3 Sep 2014 · 8,759 accessesView PDFCite