Impact of Vitamin B17 Against Growth of Colitis Bearing Mice Induced Variations in Colon Structure, AFP, CEA and PCNA Immunoreactivity

Colitis alludes to inflammation of the internal coating of the colon that accompanied clinically through abdominal pains, diarrhea, weight loss, nausea. Current study aimed to study the impact of vitamin B17 against growth of colitis bearing mice induced variations in colon structure, AFP, CEA and PCNA immune reactivity. Forty female Swiss albino mice separated into 4 groups (Control, vitamin B17, colitis and post treated colitis with vitamin B17 groups). Our results revealed significant increase in serum AFP, CEA, colon injury and PCNA expressions. In contrast; post treated colitis with vitamin B17 improved the colon functions and structure, inhibit the proliferations, AFP and CEA. If established in human beings, these outcomes could recommend that; vitamin B17 can be utilized as an adjuvant treatment with chemotherapy drugs.