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134 results for “toxic effect”
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Research ArticleOpen accessPhrase in the titleEvaluation of the Toxic Effects of Dihydroartemisinin on the Vital Organs of Wistar Albino RatsA. U. Utoh-Nedosa, P. A. Akah, T. C. Okoye, C. O. OkoliProblem statement: The current surge in the use of Artemisinin based Combination Therapy (ACT) in the treatment of falciparium resistant malaria in the tropics and the potentials of Dihydroartemisinin (DHA), a member of the artemisinin family, to produce toxic effect in the vital organs (such as the liver, heart, lungs, intestine, spleen kidney and blood cells) necessitated this research. Approach: … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 9,181 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleAssessment of the Toxic Effects of Chitosan-Coated Magnetite Nanoparticles on Drosophila melanogasterDoris Vela, Jonathan Rondal, Sofía Cárdenas et al.Nanoparticles are a cause for concern because of their potential toxic effects on human health and the environment. The aim of this study was to assess the toxic effect of chitosan-coated magnetite nanoparticles (11.00±4.7 nm) on Drosophila melanogaster through the observation of hemolymph composition, DNA damage, larval survival and lifespan of flies. Chitosan-coated magnetite nanoparticles were synthesized by co-precipitation method. … …American Journal of Applied Sciences, Vol. 17, Issue 1 · 25 Sep 2020 · 7,882 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleABSENCE OF VISIBLE TOXIC EFFECTS ACCOMPANYING THE SHORT-TERM ADMINISTRATION OF AN AQUEOUS EXTRACT OF ALLIUM SATIVA LINN. IN MALE SPRAGUE-DAWLEY RATSJ. Asiedu-Gyekye Isaac, Awortwe Charles, A. Antwi DanielAllium sativum is cultivated in the northern part of Ghana and has gained widespread use as chemoprotective, in curing hypertension, impotence and erectile dysfunction. The multipurpose use together with its aphrodisiac activity has resulted in the widespread use of this plant medicine both in meals and as herbal medications. Safety assessment of this plant however is rare. The present study … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 30 Jan 2014 · 7,577 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleAssessing the Toxic Effects of Topik80ec on Rabbit Testicular Morphometry and HistologySamia Rebahi, Alouani Abdelouahab, Meguini Mohamed Nadir et al.This study aimed to investigate the toxic impact of Topik80ec on rabbit testes through morphometric and histological analyses. Twenty-four adult male domestic rabbits (Oryctolagus cuniculus) were used, where three experimental groups, G1, G2, and G3, were assigned and provided escalating dosages of Topik80 EC for a duration of four weeks, while one group served as the control group and received … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 14 Sep 2024 · 5,015 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleBiochemical and Genetic Responses of Fungi to the Toxic Effect of Synthetic and Natural FungicidesMarÍa-Elena Báez-Flores, Rosalba Troncoso-Rojas, Martin-Ernesto Tiznado-HernándezThe objective of the present review is to analyze the molecular basis of fungicide resistance mechanism to both synthetic fungicides and the natural fungicides isothiocyanates. The review is focused mainly on Alternaria sp., but whenever available, similar studies in other fungi have been included. Fungal resistant strains to dicarboximide and phenylpyrrole fungicides have been found to contain mutations in one … …American Journal of Agricultural and Biological Sciences, Vol. 3, Issue 1 · 31 Mar 2008 · 8,118 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleDose-Dependent Neurotoxic Effects of Monosodium Glutamate and its Potential Genetic Transmission in MiceYanan Zou, Qiong Liang, Lu Liu et al.This study aimed to preliminarily investigated the neurotoxic effects of monosodium glutamate on mice and their pups, and the potential possibility of a genetic mechanism influencing the pups. In this study, mice were given different doses of Monosodium Glutamate (MSG) at doses of 2.0 or 4.0 g/kg body weight for 10 continuous days, and its impacts on both the mice … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 14 Nov 2025 · 3,031 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleTherapeutic Effects of Turnera diffusa Extract Against Amitriptyline-Induced Toxic Hepatic InflammationAhmed F. Hasan, Thulfiqar F. Mutar, Ehab Moustafa Tousson, Shatha Ghazi FelembanTricyclic Antidepressants Including Amitriptyline (AMI), stop the reabsorption of norepinephrine and serotonin, so the levels of transmitters is elevated in the brain to lead to several side effects. Therefore, current study aimed to assay liver dysfunction that attended by AMI administration and monitoring of damiana Turnera diffuse role as adjuvant therapy to improving amitriptyline hepatic effects in male rats. 60 … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 29 Jun 2021 · 8,286 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleHepatoprotective Effect of N-Acetylcystiene on the Toxic Hazards of titanium Dioxide NanoparticlesHossam Fouad Attia, Mohamed Mohamed Soliman, Gamal Hassan Abdel-Rahman et al.The present study was directed to evaluate the toxic effects of orally administered titanium dioxide naonparticles (TiO2) on liver of male albino rats and to evaluate the ameliorative effects of N-acetylcysteine (NAC). Forty adult male albino rats were divided into 4 groups; control group, NAC group, TiO2 group and TiO2/ NAC group. Rats were administered either TiO2 (1200 mg kg-1 … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 26 Sep 2013 · 8,133 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Health and Toxic Adverse Effects of Fusarium Fungal Mycotoxin, Fumonisins, on Human PopulationW. M. Wan Norhasima, A. S. Abdulamir, F. Abu Bakar et al.Problem statements: Fumonisin was a mycotoxin produced mainly by fungi belonging to the genus Fusarium in various foods and feeds. They occurred worldwide and were found predominantly in corn and in corn-based animal feeds and also can be found in other crops. Contamination of food and feed with fumonisins has been implicated in and associated with a number of diseases … …American Journal of Infectious Diseases, Vol. 5, Issue 4 · 31 Dec 2009 · 9,030 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIndications of Potential Toxic/Mutagenic Effects of World Trade Center Dust on Human Lung Cell CulturesConstantino G. Lambroussis, Barbara D. Soares, Sergio Perez et al.Problem statement: Respiratory complications have been linked with exposure to dust particulates after the tragedy of September 11th, 2001 at the World Trade Center (WTC) site. Approach: The purpose of these experiments was to investigate the extent of cellular damage resulting from WTC dust exposure. Results: This research project was conducted with human lung fibroblast cells exposed to WTC dust. … …OnLine Journal of Biological Sciences, Vol. 9, Issue 3 · 30 Sep 2009 · 7,394 accessesView PDFCite