23 results for “synthesized compounds”

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Research ArticleOpen accessIn the keywordsDesign, Synthesis, Biological Screening and Structure Activity Relationship Study of 4, 6-Dimethyl-2-(Substituted) Mercapto-3-(Substituted) Pyridines as Anti Tubercular AgentsMehul M. Patel, Mahesh T. ChhabriyaProblem statement: Tuberculosis is a leading global mortality factor which has not been effectively controlled, with 1.7 million deaths per year and 8.9 million new cases. Aerobic microbe Mycobacterium tuberculosis H37Rv (MTB) is the causative agent of tuberculosis. Although many active antitubercular agents have since been developed, drug resistance will continue to be a problem. Therefore, there is a clear … …American Journal of Infectious Diseases, Vol. 7, Issue 3 · 3 Nov 2011 · 7,430 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsSynthesis, Characterization and Biological Activities of Organotin (IV) Methylcyclohexyldithiocarbamate CompoundsNormah Awang, Ibrahim Baba, Bohari M. Yamin et al.Problem statement: The growing interest in the chemistry of sulphur donor ligands are due to their encouraging anticancer, antibacterial and antifungal activities as well as their widespread industrial application. Dithiocarbamates belong to this class and much attention has been paid to them. Approach: Novel organotin compounds with the molecular formula RmSn[S2CN(CH3)(C6H11)]4-m (where m = 2, R = CH3, C2H5; m … …American Journal of Applied Sciences, Vol. 8, Issue 4 · 18 Apr 2011 · 9,210 accessesView PDF Cite

Research ArticleOpen accessIn the abstractBiogenic Silver Nanoparticles Produced by Bacteria Isolated from University Campus Environment Soil Samples in Ras Al KhaimahPooja Shivappa, Grisilda Vidya Bernhardt, Sheela Haridas, Michael V MagaogaoSilver is observed to be comprised of a huge percentage ofsilver oxide and the utilization of silver and silver salts is in practicesince ancient human civilization. Silver nanoparticles remain to be potentialantifungal, antibacterial, anti-inflammatory, and antiviral agents. Further, itis demonstrated that silver nanoparticles have been involved in arresting thegrowth of several bacterial species thereby reducing their harmful effects.Micro-organisms are being … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 3 · 5 Sep 2022 · 5,870 accessesView PDF Cite

Research ArticleOpen accessIn the abstractTotal Phenolic Composition and Antioxidant Activity of Silver Nanoparticles using Aqueous Extract of Chilca Leaves (Baccharis latifolia)Fernanda Pilaquinga, Camila Granja, Eliza Jara et al.The importance of studying polyphenols as natural antioxidants has encouraged the search for new methods of rapid, simple analysis. The synthesis of silver Nanoparticles (Ag NPs) using plant extracts has been presented as an alternative to determine the presence of polyphenolic compounds. In this study, aqueous extract of chilca (Baccharis latifolia), an endemic plant species from South America known for … …American Journal of Applied Sciences, Vol. 18, Issue 1 · 16 Apr 2021 · 8,341 accessesView PDF Cite

Research ArticleOpen accessIn the abstractComputer Aid Screening for Potential Antimalarial Choroquinone Compounds as Covid 19 Utilizing Computational Calculations and Molecular Docking StudyAsmaa Aboelnaga, Asmaa M. Fahim, Taghreed H. EL-SayedClick reaction of 4,7-dichloroquinoline (1) with thiosemicarbazide (2) to afford the corresponding 2-(7-chloroquinolin-4-yl)thiosemicarbazide (3) utilized ultrasonic irradiation which can cyclized easily with ethylacetoacetate to give the 3-(7-chloroquinolin-4-ylamino)-tetrahydro-6-methyl-2-thioxopyrimidin-4(1H)-one (4) via nucleophilic substitution reaction. The synthesized compounds was examined in vitro antimalarial activity with IC50 = 11.92, 25.37 μg/mL against chloroquinone drug. Furthermore, the theoretical investigation of most active compounds CQT and … …OnLine Journal of Biological Sciences, Vol. 20, Issue 4 · 30 Nov 2020 · 6,568 accessesView PDF Cite

Research ArticleOpen accessIn the abstractComparative Effect of Ulvan and Biosynthesized Silver Nanoparticles on Different Cell Lines Cytotoxicity and Gene ExpressionHadear Hanie Amin, Mohammed Ahmed Taha AbdelreheemUntil now, researchers searching for compounds that contribute for treating the most serious disease of this age, cancer. Researchers hope to contribute to this through this research. Activities of both Ulvan extracted from Ulva lactuca and silver nanoparticles (Ag-NPs) were examined against seven different cancer cell types called (Caco2 cells, A549 cells, Mcf7 cells, Hep2 cells, HepG2 cells, PC3 cells, … …OnLine Journal of Biological Sciences, Vol. 20, Issue 2 · 30 Jun 2020 · 6,675 accessesView PDF Cite

Research ArticleOpen accessIn the abstractSynthesis and Characterization of Cobalt, Iron and Ruthenium Catalysts for the Production of Synthetic DieselDayna M. Ortiz Rodríguez, María del C. Cotto-Maldonado, José Duconge Hernández et al.Fossil fuels are currently the world's leading source of energy. Environmental legislations, the high price of fossil fuels, the concern about the supply of these fuels and technological development, makes it necessary to search for alternative sources of energy. The production of clean liquid fuels, such as synthetic diesel from synthesis gas, by Fischer-Tropsch (FT) method, is considered a very … …American Journal of Engineering and Applied Sciences, Vol. 13, Issue 2 · 29 Apr 2020 · 7,248 accessesView PDF Cite

Research ArticleOpen accessIn the abstractScreening and Characterization of Sponge-Associated Bacteria Producing Bioactive Compounds Anti-Vibrio sp.Aris Tri Wahyudi, Jepri Agung Priyanto, Wenang Maharsiwi, Rika Indri AstutiIn Indonesia, vibriosis is the main disease in shrimp. This disease is caused by Vibrio sp that may decrease the productivity of shrimp cultivation. Thus, exploration for new bioactive compounds as vibriosis biocontrol agent is necessary. Marine sponge-associated bacteria is one of many sources for bioactive compounds. The aim of this study was to screen marine sponge-associated bacteria producing anti-Vibrio … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 3 · 5 Oct 2018 · 10,357 accessesView PDF Cite

Research ArticleOpen accessIn the abstractDesign and Synthesis of Diaminotriazines as Anti-Tuberculosis DHFR InhibitorsArundhati C Lele, Archana Raju, M.K. Ray et al.A series of novel 2,4 diamino-s-triazine was designed as potential Mycobacterium tuberculosis (Mtb) Dihydro folate reductase inhibitors. The synthesized compounds were evaluated in whole cells by employing Resazurin Microtitre Plate Assay (REMA) against Mtb H37Rv, using known DHFR inhibitors Methotrexate and Trimethoprim as standard drugs. The most active compound in the whole cell assay was selected for DHFR enzyme assay … …Current Research in Drug Discovery, Vol. 1, Issue 2 · 26 Jan 2015 · 14,716 accessesView PDF Cite

Research ArticleOpen accessIn the abstractFACILE SYNTHESIS OF IN-VIVO INSECTICIDAL AND ANTIMICROBIAL EVALUATION OF BIS HETEROCYCLIC MOIETY FROM PET WASTEAsmaa Mahmoud Fahim, El Sayed Mohamed Yakout, Galal Abd ElMohein NawwarRecycling of Plastic Solid Waste (PSW) using green tool such as solar energy which used for degradation of plastic solid bottles (PET) to afford terepthalic acid which estrified using butanol/H2SO4 to afford dibutyl terephthalate as a starting material which has been chemically modified to yield new bis (1,2,4-triazole-3-thiol) 5, 1,3,4-oxadiazole 6, 8, 15, 1,3-thiazolidine 9, 1 H-pyrazole 10, 11 and … …OnLine Journal of Biological Sciences, Vol. 14, Issue 3 · 21 Aug 2014 · 7,373 accessesView PDF Cite