12 results for “selective inhibition”

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Research ArticleOpen accessEvery word in the titleSelective Lymphocyte Activation and Inhibition of In Vitro Tumor Cell Growth by Novel MorphinansRicardo Gomez-Flores, Kimberly R. Vietti, William J. Dunn et al.Opioids can suppress immune functions and increase susceptibility to developing cancer and infectious diseases. Recently, novel opioid compounds have been synthesized that lack immunosuppressive effects. We evaluated the effects of morphinans with substituted pyrimidine (methyl, phenyl, hydroxy, and amino groups) and pyrazole groups on in vitro rat thymic lymphocyte and splenic macrophage functions, and tumor cell growth. We observed that … …American Journal of Immunology, Vol. 2, Issue 1 · 5 Mar 2005 · 7,078 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsEvaluation of the Use of Rice Bran Compost for Eco-friendly Weed Control in Organic Farming SystemsM.A.I. Khan, K. Ueno, S. Horimoto et al.Rice bran compost (RC) was evaluated under greenhouse and field conditions for eco-friendly weed control of vegetable crops in organic farming systems. RC was applied 7 days before spinach seed sowing, at the rate of 0% (control), 10%, 20% and 30% of soil (v/v) in the greenhouse and 2 kg m-2 under field conditions. RC significantly controlled the number and … …American Journal of Environmental Sciences, Vol. 3, Issue 4 · 31 Dec 2007 · 7,927 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsEvaluation of the Upland Weed Control Potentiality of Green Tea Waste-Rice Bran Compost and Its Effect on Spinach GrowthM.A.I. Khan, K. Ueno, S. Horimoto et al.This study evaluated the upland weed control potentiality, germination inhibition ability and growth suppression efficiency of the five combinations of green tea waste - rice bran compost (GRC). GRC was prepared by mixing green tea waste and rice bran at five ratios, and allowed to decompose for 5 mo. Application of GRC suppressed weed growth up to 93.4% in number … …American Journal of Agricultural and Biological Sciences, Vol. 2, Issue 3 · 30 Sep 2007 · 8,203 accessesView PDF Cite

Research ArticleOpen accessIn the abstractSelective Susceptibility of Human Bladder Transitional Cell Carcinoma T24 Cells towards NBD PeptideSankari Durairajan, Charles Emmanuel Jebaraj Walter, Kalaiselvi Periyandavan et al.Bladder cancer is a recurrent disease that often develops chemoresistance and is on the rise in developing countries. After diagnosis surgery followed by immunotherapy and/or chemo- radiation therapy are the available treatments. These treatments do not provide protection against disease progression or recurrence thus highlighting the need to identify and develop drugs that are capable of inhibiting bladder cancer. T24 … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 20 Apr 2020 · 7,787 accessesView PDF Cite

Review ArticleOpen accessIn the abstractTrazodone: A Review of Its Pharmacological Properties and Its Off-Label Use in Dogs and CatsBunna Chea, Mario GiorgiTrazodone is approved by the Food and Drug Administration (FDA) for the treatment of depression and anxiety in humans, it can perform these functions due to its selective serotonin receptor antagonism and reuptake inhibition properties. Trazodone has not been approved for animals by the FDA but it is legally prescribed by veterinarians as an off-label drug for dogs and cats. … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 4 · 31 Oct 2017 · 10,858 accessesView PDF Cite

EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,862 accessesView PDF Cite

EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,281 accessesView PDF Cite

EditorialOpen accessIn the abstractAre Heat Shock Proteins Druggable Candidates?Tawanda Zininga, Addmore ShonhaiBanumathy, G., V. Singh, S.R. Pavithra and U. Tatu, 2003. Heat shock protein 90 function is essential for Plasmodium falciparum growth in human erythrocytes. J. Biol. Chem., 278: 18336-18345. DOI: 10.1074/jbc.M211309200 Brehmer, D., S. Rudiger, C.S. Gassler, D. Klostermeier and L. Packschies et al., 2001. Tuning of chaperone activity of Hsp70 proteins by modulation of nucleotide exchange. Nature Structural Molecular … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 4 · 2 Dec 2014 · 8,166 accessesView PDF Cite

Research ArticleOpen accessIn the abstractIn Vitro Interaction of 5-Hydroxytrptamine with Cytosolic Molybdenum Hydroxylases as a Potential Inhibitor for Initial Rates ActivitiesAbdullah M. Al-Mohizea, Abd El-Galil E. Amr, Mohamed A. Al-OmarProblem statement: The role of 5-HT has been investigated in many behavioral activities. Thus, studies using raphe lesion showed that 5-HT is involved in sleep, general activity levels, habituation, aggression, pain sensitivity and morphine analgesia, avoidance behavior, self-stimulation and water consumption. Approach: The metabolic interaction between serotonin (5- hydroxytrptamine) and indole-3-aldehyde and xanthine via aldehyde oxidase (EC 1.2.3.1) and xanthine … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 7,026 accessesView PDF Cite

Research ArticleOpen accessIn the abstractIncreased Production of Nitric Oxide Contributes to Renal Oxidative Stress in Endotoxemic RatBahar Tunçtan, Belma Korkmaz, Hatice Yıldırım et al.Overproduction of reactive oxygen and nitrogen species leads to oxidative stress and decreased total antioxidant capacity, which is responsible for high mortality from several diseases such as endotoxic shock. Nitric oxide (NO) produced by inducible NO synthase (iNOS) during endotoxemia is the major cause of vascular hyporeactivity, hypotension and multiple organ failure. In this study, we investigated whether increased production … …American Journal of Infectious Diseases, Vol. 1, Issue 2 · 30 Jun 2005 · 8,638 accessesView PDF Cite