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28 results for “oxidative stress markers”
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Research ArticleOpen accessPhrase in the titleTHE IMPACT OF ANTIOXIDANTS ON INFLAMMATION AND OXIDATIVE STRESS MARKERS IN OSTEOARTHRITIS RAT MODEL: SCANNING ELECTRON MICROSCOPE INSIGHTSEl Hassan Heidar, FareedF Al Faya, Waleed N. Hassan et al.Osteoarthritis (OA) is characterized by degradation of matrix and destruction of articular cartilage. Articular chondrocytes are solely responsible for the production and maintenance of the extracellular matrix. Therefore, chondrocyte disruption is implicated in cartilage degeneration. Numerous studies have shown that antioxidant treatments are promising therapeutics in cases of OA. This study was designedto examine whether vitamin E protects rat articular … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 19 May 2014 · 7,616 accessesView PDFCite
Research ArticleOpen accessIn the keywordsOxidative Stress in Autism: Elevated Cerebellar 3-nitrotyrosine LevelsElizabeth M. Sajdel-Sulkowska, Boguslaw Lipinski, Herb Windom et al.It has been suggested that oxidative stress and/or mercury compounds play an important role in the pathophysiology of autism. This study compared for the first time the cerebellar levels of the oxidative stress marker 3-nitrotyrosine (3-NT), mercury (Hg) and the antioxidant selenium (Se) levels between control and autistic subjects. Tissue homogenates were prepared in the presence of protease inhibitors from … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 17,119 accessesView PDFCite
Research ArticleOpen accessIn the abstractAluminium-Induced Hepatotoxicity and the Protective Role of Withania somnifera (Ashwagandha) in Wistar RatsAnchana Babu, Rekha D Kini, Nayanatara Arun Kumar, Megha GokulAluminium is a widely distributed environmental contaminant whose chronic exposure leads to accumulation in multiple organs, including the liver, resulting in oxidative stress and tissue damage. When reactive oxygen species production exceeds the body's antioxidant defense capacity, cellular injury ensues — a mechanism central to aluminium-induced hepatotoxicity. Withania somnifera (Ashwagandha), an evergreen herb of the Solanaceae family widely cultivated in … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 6 Apr 2026 · 1,449 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetermination of the Probiotic Potential and Metabolic Function of Lactobacillus Strains for Healthy Calf RearingRaya Myktybayeva, Serkan Özkaya, Elif Rabia Şanlı et al.This research investigstes the impact of probiotic supplementation on the growth performance, health status, and physiological traits in Holstein calves. A total of thirty calves were randomly divided into three experimental groups: a control group and two treatment groups receiving probiotics at doses of 1 g/10 kg and 1.5gt/10 kg live weight. Key indicators, including Live Weight (LW), Body Measurements … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 23 Jul 2025 · 3,626 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of the Renoprotective Effects of Valsartan in Methotrexate-Induced Acute Kidney Injury in RatsDina KutbiMethotrexate (MTX) is a widely used chemotherapeutic agent known for its nephrotoxic effects, which can lead to acute kidney injury in hospitalized patients. However, the mechanism by which MTX induces nephrotoxicity is not entirely clear, but it is believed to involve oxidative stress and direct toxic effects on renal tubules. Valsartan, an angiotensin II receptor blocker, has been shown to … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 4 May 2024 · 4,571 accessesView PDFCite
Research ArticleOpen accessIn the abstractSelenium Enriched Peanut Protein Alleviates Alcohol-Induced Liver Damage in Mice by Modulating the Composition of the Gut MicrobiotaLin Gao, Jiawei Yuan, Yuhuan Cheng et al.Alcohol Use Disorder (AUD) is one of leading external causes of mortality. Selenium-enriched Peanut Protein (SePP) is a type of Se compound present in Se-enriched plants. Our previous studies showed that SePP possesses potential therapeutic properties and could alleviate alcohol-induced AML-12 cytotoxicity. It spurred us to determine the underlying mechanisms and roles of SePP on gut microbiota. Here, ICR mice … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 4 · 23 Dec 2021 · 6,230 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Crassocephalum bauchiense Ethanolic Extract on Reproductive Parameters in Rabbit Does Exposed to Potassium DichromateChongsi Margaret Mary Momo, Manfo Tsague Faustin Pascal, Nyambi Pasima et al.The present study was undertaken to evaluate the effects of Hutch leaves Ethanolic Extract (EE) on reproductive parameters, toxicity biochemical markers and oxidative stress indicators in does exposed to Potassium Dichromate (PD). Thirty-six nulliparous sexually mature does of eight months; weighing 2.80-3.00 kg were divided into six groups of six animals, comparable in terms of Body Weight (BW). After mating, … …American Journal of Animal and Veterinary Sciences, Vol. 16, Issue 2 · 19 May 2021 · 6,819 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntioxidant Properties and Dose-Dependent Effects of Monkey Fruits (Artocarpus lakoocha) against Paracetamol-Induced Hepato-Renal Toxicity in RatsMd. Yousuf Ali, Md. Reaz Morshed, Md. Sakib Hossen et al.In this study, the antioxidant potentials and protective effect of ethanolic extract of monkey fruits (Artocarpus lakoocha) (AL) was investigated against paracetamol-induced toxicity in rats. AL which contains high concentration of polyphenols, flavonoids, tannins and protein, exhibited high radical scavenging activity and ferric reducing antioxidant power. Administration of paracetamol (500 mg/kg) for seven consecutive days caused severe oxidative stress in … …American Journal of Pharmacology and Toxicology, Vol. 13, Issue 1 · 26 Nov 2018 · 8,337 accessesView PDFCite
InvestigationOpen accessIn the abstractRegularities of the Oxidative Stress Processes in Case of Bleedings from Acute and Chronic Ulcers of the Stomach and DuodenumEkaterina Vladimirovna Silina, Mukimdjon Ahmadzhonovich Sobirovz, Sergey Brankovich Bolevich, Victor Aleksandrovich StupinThe main aim of the study was to determine ways of improving the results of treating patients with ulcer bleeding of various nature and severity. It was provided by the system study of free radical processes and evaluation of the effectiveness of timely antioxidant therapy. Material and methods. The study included 153 patients aged 18-94 years with acute and chronic … …OnLine Journal of Biological Sciences, Vol. 18, Issue 2 · 4 May 2018 · 7,416 accessesView PDFCite
Research ArticleOpen accessIn the abstractProduction and Characterization of Exopolysaccharide from Novel Bacillus sp. M3 and Evaluation on Development Sub-Chronic Aluminum Toxicity Induced Alzheimer’s Disease in Male RatsMohsen M.S. Asker, Abeer Y. Ibrahim, Manal G. Mahmoud, Saher S. MohamedThe number of patients suffering from Alzheimer’s Disease (AD) all over the world is rising continually and becomes one of the biggest challenges for most societies throughout the world. The potential of peripheral biochemical markers as complementary tools in the neuron-phsychiatric evaluation of these patients has claimed further attention. The aims of our study were to isolate the bacteria that … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 2 · 31 May 2015 · 7,216 accessesView PDFCite