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Research Article · Open access · Published 23 July 2025

Determination of the Probiotic Potential and Metabolic Function of Lactobacillus Strains for Healthy Calf Rearing

Raya Myktybayeva1, Serkan Özkaya2, Elif Rabia Şanlı2, Hatice İlkay Yaşar2, Cevdet Gökhan Tüzün2, Özgür Koşkan2, Togzhan Boranbayeva3, Zhassulan Otebayev4 & Shokhan Alpeisov4

OnLine Journal of Biological Sciences, Volume 25, Issue 3, pp. 607–616 · doi.org/10.3844/ojbsci.2025.607.616

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Abstract

This research investigstes the impact of probiotic supplementation on the growth performance, health status, and physiological traits in Holstein calves. A total of thirty calves were randomly divided into three experimental groups: a control group and two treatment groups receiving probiotics at doses of 1 g/10 kg and 1.5gt/10 kg live weight. Key indicators, including Live Weight (LW), Body Measurements (BMs), Feed Intake (FI), Feed Conversion Ratio (FCR), haematological and biochemical blood markers, and oxidative stress indicators were monitored. Results demonstrated that probiotic addition enhanced growth rates, reduced disease incidence and diarrhoea episodes, and promoted rumen development, although changes in FCR and BMs were not statistically significant. Hematological and biochemical profiles remained within physiological norms across all groups, affirming the safety of the supplementation strategy. Overall, findings support use of probiotics as an effective nutritional approach to boost health and growth in Holstein calves without causing adverse effects.

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Open access. This article is licensed under a Creative Commons Attribution 4.0 International Licence (CC BY 4.0), as printed on the article, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original authors and the source. No permission is needed.

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Myktybayeva, R., Özkaya, S., Şanlı, E. R., Yaşar, H. İ., Tüzün, C. G., Koşkan, Ö., Boranbayeva, T., Otebayev, Z. & Alpeisov, S. (2025). Determination of the Probiotic Potential and Metabolic Function of Lactobacillus Strains for Healthy Calf Rearing. OnLine Journal of Biological Sciences, 25(3), 607–616. https://doi.org/10.3844/ojbsci.2025.607.616

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Determination of the Probiotic Potential and Metabolic Function of Lactobacillus Strains for Healthy Calf RearingOnLine Journal of Biological Sciences · Volume 25, Issue 3 · pp. 607–616 · CC BY 4.0Download