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Research ArticleOpen accessPhrase in the titleHormonal and Metabolic Disorders of Human Immunodeficiency Virus Infection and Substance AbuseJag H. Khalsa, Frank Vocci, Adrian DobsThere are an estimated 200 million users of an illicit drug in the world today. In addition, an estimated 40 million people are infected with the human immunodeficiency virus (HIV) and an estimated 180 million people are infected with the hepatitis C virus (HCV). Both the use of an illicit drug and the co-occurrence of infections are associated with a … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,715 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleRamadan Fasting Diet Entailed a Lipid Metabolic Disorder Among Type 2 Diabetic Obese WomenMéghit Boumédiène Khaled, Slimane BelbraouetWe designed this study to assess the effect of diet during Ramadan fasting on body weight and on serum lipid components in type 2 diabetic obese women. During Ramadan of 2005, 89 diabetic women receiving oral treatment (BMI = 33.20±3.01 kg m-2), aged 52 (±5 years), were selected. The study was carried out over 3 periods-, before (T1: pre-fasting), during … …American Journal of Applied Sciences, Vol. 6, Issue 3 · 31 Mar 2009 · 7,861 accessesView PDFCite
Research ArticleOpen accessIn the keywordsLifestyles and Migraine AttackHui Jun Chih, Wenbin LiangProblem statement: Migraine is a headache disorder of serious public health concerns as many sufferers are permanently disabled and incapable of carrying out simple daily routines. Migraine is contributed by biological and lifestyle factors. Understanding the association between these factors and migraine, particularly the modifiable lifestyle factors, can reduce the prevalence of this chronic disease and ease the burden on … …Current Research in Medicine, Vol. 2, Issue 2 · 2 Dec 2011 · 7,517 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA Novel Rodent Model of Autism: Intraventricular Infusions of Propionic Acid Increase Locomotor Activity and Induce Neuroinflammation and Oxidative Stress in Discrete Regions of Adult Rat BrainDerrick F. MacFabe, Karina Rodríguez-Capote, Jennifer E. Hoffman et al.Innate neuroinflammatory changes, increased oxidative stress and disorders of glutathione metabolism may be involved in the pathophysiology of autism spectrum disorders (ASD). Propionic acid (PPA) is a dietary and gut bacterial short chain fatty acid which can produce brain and behavioral changes reminiscent of ASD following intraventricular infusion in rats. Adult Long-Evans rats were given intraventricular infusions of either PPA … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 12,613 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSerum Ornithine Carbamoyltransferase Activity and Correlation with Fatty Liver in Dairy Cows with Displaced AbomasumKen Onda, Reiichiro Sato, Yosuke Sasaki et al.Ornithine Carbamoyltransferase (OCT) is a hepatocyte-specific enzyme; elevated serum activity indicates liver damage. Displaced abomasum frequently occurs around the time of parturition in dairy cattle and is associated with fatty liver. We analyzed serum OCT activities to investigate the relationship between displaced abomasum and fatty liver. Lactating Holstein cows, 75 clinically healthy and 22 with displaced abomasum, were used. Serum … …American Journal of Animal and Veterinary Sciences, Vol. 11, Issue 3 · 13 Jul 2016 · 7,660 accessesView PDFCite
Research ArticleOpen accessIn the abstractAdipokines Overview: The Major Component of Immune DysregulationAnastasia Vladimirovna Poznyak, Daria Dmitryevna Borodko, Stanislav Anatolievich Antonov et al.Purpose of Review: Obesity is increasingly recognized as an immune endocrine disorder rather than only a metabolic condition. This review critically examines how adipokines particularly adiponectin, resistin, adipsin, and chemerin mediate the interplay between obesity and autoimmunity. Unlike previous reviews that broadly surveyed cytokines, our focus is on comparative roles of specific adipokines across multiple autoimmune diseases. Recent Findings: Evidence … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 11 Aug 2026 · 879 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Intricate Relationship between Obesity and Type 2 DiabetesAnastasia V. Poznyak, Elizaveta M. Pleshko, Aleksandra S. Utkina et al.The rising prevalence of obesity and type 2 diabetes mellitus (T2DM) has emerged as one of the most pressing global public health challenges, profoundly impacting various demographic groups worldwide. This review synthesizes recent epidemiological data and explores the intricate biochemical mechanisms linking obesity to T2DM. We highlight the multifactorial nature of obesity, characterized by excessive adipose tissue, systemic inflammation, and … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 9 Aug 2026 · 455 accessesView PDFCite
Research ArticleOpen accessIn the abstractComputational Prediction of Diabetic Nephropathy-Associated Comorbidities and Their Key Genes by Analyzing RNA-Seq DataChaity Paul, Md. Ashiq Uddin, Rupa Dey et al.Diabetic Nephropathy (DN) is a complex health condition that leads to various kidney diseases. According to the World Health Organization, over 2 million deaths have been reported due to diabetes and diabetes related kidney diseases in 2021. And at the recent 78th World Health Assembly, chronic kidney disease was reported to be one of the most common diabetes-related complications, and … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 19 May 2026 · 1,667 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Metaheuristic-Optimized Feature Selection for Early-Stage Diabetes Prediction With SHAP-Guided Insight into Influential AttributesEsmay Azam Rochy, Jannatul Ferdaus, Uzzal Biswas et al.Diabetes is a metabolic disorder that causes elevated blood glucose. This long-term health condition can lead to cardiovascular diseases, stroke, kidney failure, visual impairment, neuropathy, and even death in critical cases. So, a Computer-Aided Diagnostic (CAD) system is necessary to diagnose diabetes automatically. A clinician can utilize a machine learning-based CAD system that automatically diagnoses many people. This paper will … …Journal of Computer Science, Vol. 22, Issue 2 · 24 Feb 2026 · 1,736 accessesView PDFCite
Literature ReviewOpen accessIn the abstractCorrelation of Atherosclerosis and Osteoarthritis, the Role of Inflammation in the Pathogenesis of Osteoarthritis and AtherosclerosisAnastasia V. Poznyak, Nikolay A. Orekhov, Aleksandra Sergeevna Utkina et al.Cardiovascular Diseases (CVD) rank among the leading causes of death globally, accounting for a substantial proportion of mortality rates and affecting millions of individuals. Risk factors such as ageing, obesity, diabetes and a sedentary lifestyle contribute significantly to the prevalence of CVD. Osteoarthritis (OA), on the other hand, is one of the most common joint disorders, affecting a large segment … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 15 Feb 2026 · 1,769 accessesView PDFCite