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14 results for “malaria parasite”
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Research ArticleOpen accessPhrase in the titleHAEMATOLOGICAL PROFILE OF PREGNANT WOMEN INFECTED WITH MALARIA PARASITES AT FEDERAL TEACHING HOSPITAL ABAKALIKI, EBONYI STATEAlo Moses Nnnaemeka, Okonkwo Eucharia Chinyere, Anyim Chukwudi, I. Ugah UchennaMalaria in pregnancy is a major public health problem in endemic areas of sub-Saharan Africa and has important consequences on birth outcome. There are subtle and substantial changes in hematological parameters of malaria in pregnancy. This work is designed to ascertain the impact of malaria in pregnant women visiting Federal Teaching Hospital Abakaliki II. Out of the 100 pregnant women … …Current Research in Microbiology, Vol. 5, Issue 1 · 16 Jul 2014 · 7,848 accessesView PDFCite
Research ArticleOpen accessIn the keywordsRespiratory Tract-Widening Effects of Dihydroartemisinin in Wistar Albino RatsUtoh-Nedosa Uchechukwu, Njoku Goddy, S. Nedosa Kenechi et al.Problem statement: Artemisinin-based anti-malarials are currently widely used in Asia and Africa. Not much is known about the systemic effect of dihydroartemisinin. This study therefore examine the effect of dihydroartemisinin on the lungs of Wistar albino rats. Approach: Five dosages of Dihydroartemisinin (DHA) were administered by oral intubation for 5 days to 5 test and 4 control Wistar albino rats. … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 2 · 17 Aug 2011 · 7,515 accessesView PDFCite
Case ReportOpen accessIn the abstractA Case Report of Severe Malaria Due to Plasmodium falciparum Malaria Complicated by Symmetrical Peripheral Gangrene (SPG) at the Matlaboul Fawzaini National Hospital Center, Touba, SenegalJules Yindoni Zande, Ndeye Fatou Ngom et al.Malaria remains a major public health problem worldwide, particularly in Africa. Symmetrical Peripheral Gangrene (SPG) is a distal ischemic lesion affecting at least two extremities in the absence of proximal arterial obstruction and vasculitis. It is a rare and severe clinical entity. Its association with malaria is rare, with approximately 27 cases reported worldwide, mostly in Asia. A 15-year-old male … …American Journal of Infectious Diseases, Vol. 21, Issue 1 · 22 Jan 2026 · 2,806 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn silico and in vitro Structural Analysis on the Interaction of Calmodulin and Calmodulin-Binding Motif of FKBP35 from Plasmodium knowlesiSazlinawatie Aladin, Cahyo Budiman et al.FK506-binding protein 35 (FKBP35) is a peptidyl-prolyl cis-trans isomerase found in Plasmodium knowlesi, a zoonotic malaria parasite responsible for concerning cases of malaria infection in East Malaysia. This protein contains a segment known as the calmodulin-binding motif (Pk-CBM), which is predicted to facilitate interaction with calmodulin from P. knowlesi (Pk-CaM). Although this interaction is considered promising for future antimalarial drug … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 10 Mar 2025 · 4,846 accessesView PDFCite
Research ArticleOpen accessIn the abstractWhy Continue Studying HRP2 and HRP3 in Malaria?María Luz Gunturiz, Pablo Enrique Chaparro, Gabriel Carrasquilla, Mónica Marcela JiménezThe main malaria control strategy is rapid and accurate diagnosis followed by effective treatment. The quality of the diagnosis is relevant, since an erroneous diagnosis can generate an increase in morbidity and mortality significantly. The World Health Organization (WHO) has recommended that all patients with suspected malaria be diagnosed by microscopy or a Rapid Diagnostic Test (RDT) before treatment. Microscopy … …American Journal of Infectious Diseases, Vol. 16, Issue 3 · 24 Aug 2020 · 6,897 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of GA3 and Shading on the Growth and Content of Artemisinin Compound in Leaf of Artemisia (Artemisia annua L.) Grown on the Medium Land of Karanganyar, IndonesiaYuni Kusumodewi, Usman Siswanto, Samanhudi, Ahmad YunusMalaria is still becomes a concern for the government of Indonesia, since this disease has affected many people. Artemisia annua L. is an aromatic plant that destroys malarial parasites, lowers fever and of which the secondary metabolite is artemisinin. Enhanced production of the artemisinin content in the whole plant is desirable. This experiment was conducted in Karanganyar, Indonesia 900m asl. … …American Journal of Applied Sciences, Vol. 14, Issue 10 · 1 Nov 2017 · 8,007 accessesView PDFCite
EditorialOpen accessIn the abstractAre Heat Shock Proteins Druggable Candidates?Tawanda Zininga, Addmore ShonhaiBanumathy, G., V. Singh, S.R. Pavithra and U. Tatu, 2003. Heat shock protein 90 function is essential for Plasmodium falciparum growth in human erythrocytes. J. Biol. Chem., 278: 18336-18345. DOI: 10.1074/jbc.M211309200 Brehmer, D., S. Rudiger, C.S. Gassler, D. Klostermeier and L. Packschies et al., 2001. Tuning of chaperone activity of Hsp70 proteins by modulation of nucleotide exchange. Nature Structural Molecular … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 4 · 2 Dec 2014 · 8,166 accessesView PDFCite
Research ArticleOpen accessIn the abstractIN VIVO ANTIPLASMODIAL ACTIVITY AND ACUTE TOXICITY OF STANDARDIZED EXTRACT OF EURYCOMA LONGIFOLIA JACK. ROOT TRADITIONALLY USED TO TREAT MALARIAEti Nurwening Sholikhah, Mahardika Agus Wijayanti, MustofaA series of studies has been conducted to prove the Eurycoma longifolia Jack. root as an antimalarial. However, the in vivo antiplasmodial activity of E. longifolia Jack. root standardized extract and its lethal dose 50% (LD50) values is unknown. In vivo antiplasmodial activity was conducted on Plasmodium berghei infected Swiss mice as malaria model with 4-day suppression methods. Sixty mice … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 27 Dec 2013 · 7,732 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Overview of Malaria ControlEmmanuel Chanda, Mulakwa Kamuliwo, Richard W. Steketee et al.Malaria remains a serious global public health problem and a leading cause of morbidity and mortality in sub Saharan Africa. In Zambia the disease is endemic with stable transmission, accounting for 40% of all out-patient attendances and is responsible for 20% deaths among children under five. Scaling up of scientifically proven high impact preventive, curative and supportive interventions and deploying … …Current Research in Medicine, Vol. 4, Issue 1 · 29 Apr 2013 · 7,960 accessesView PDFCite
Research ArticleOpen accessIn the abstractPlasmodium Pre-Erythrocytic Stages: Biology, Whole Parasite Vaccines and Transgenic ModelsKota Arun Kumar, Satish MishraMalaria remains one of the world’s worst health problems, which causes 216 million new cases and approximately 655,000 deaths every year WHO World Malaria Report, 2011. Malaria transmission to the mammalian host is initiated through a mosquito bite that delivers sporozoites into the vertebrate host. The injected sporozoites are selectively targeted to liver which is the first obligatory step in … …American Journal of Immunology, Vol. 8, Issue 3 · 13 Sep 2012 · 8,263 accessesView PDFCite