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9 results for “magnetic resonance spectroscopy”
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Research ArticleOpen accessPhrase in the titlePhysical Basis of Magnetic Resonance Spectroscopy and its Application to Central Nervous System DiseasesNicolás Fayed, Salvador Olmos, Humberto Morales, Pedro J. ModregoMagnetic Resonance Spectroscopy is based on the chemical shift property of the atom nuclei when a magnetic field is applied. This technique offers invaluable information about living tissues with special contribution to the diagnosis and prognosis of the central nervous system diseases. Concentration of several metabolites can be assessed in a reproducible manner by means of modern clinical scanners. N-acetyl-aspartate … …American Journal of Applied Sciences, Vol. 3, Issue 5 · 31 May 2006 · 7,851 accessesView PDFCite
Research ArticleOpen accessIn the abstractIsolation and Characterization of Chemical Constituents, Cytotoxicity, Antibacterial and Antioxidant Activity of the Compounds from Leptadenia hastata Roots Extract ByIsaac John Umaru, Hauwa A. UmaruThe aim of this work was to extract, isolate and characterise the chemical constituent from Leptadenia hastata roots. Fresh roots were washed and dried and was subjected to sequential maceration in polar and non-polar solvents. And introduced into rotary evaporator to concentrate the extract. Isolated compound was subjected to Thin Layer Chromatography and spectral analysis such as column and UV-Visible … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 4 · 24 Dec 2019 · 7,959 accessesView PDFCite
Research ArticleOpen accessIn the abstractSynthesis and Characterizations of MmtO-Copolymer (St-THF) NanocompositeHattab Youcef, Hakiki WahibaNanocomposites are synthesized by one or two polymers and optimized organophilic clay proportions. The aim of Synthesis of the Organophilic clay (montmorillonite) with a two monomers to get a copolytetrahydrofuran- styrene nanocomposite by insitu polymerization. Organophilic montmorillonite (MmtO) was synthesized by ion exchange between Na+ ions in the clay and HDTMAB alkylammonium cations in an aqueous medium. The MmtO were … …American Journal of Applied Sciences, Vol. 16, Issue 10 · 19 Dec 2019 · 7,116 accessesView PDFCite
Research ArticleOpen accessIn the abstractBio-Guided Study on Melastoma malabathricum Linn Leaves and Elucidation of its Biological ActivitiesMourouge Saadi Alwash, Nazlina Ibrahim, Wan Yaacob AhmadThe present study aimed to isolate and identify constituents with antibacterial activity from the Methanol extract of Melastoma malabathricum leaves (MMML) through bioassay guided fractionation. Furthermore, the study scoped to evaluate the cytotoxic effects of M. malabathricum leaves fractions for possible protective effect of antoxidative constituents present in the fractions. The MMML extract was fractionated by Vacuum Liquid Chromatography (VLC) … …American Journal of Applied Sciences, Vol. 10, Issue 8 · 24 Jul 2013 · 9,513 accessesView PDFCite
Research ArticleOpen accessIn the abstractSynthesis and Calcium Channel Blocking Activity of 1, 4-Dihydropyridine Derivatives Containing Ester Substitute and Phenyl Carbamoyl GroupBassem Sadek, Khairi Mustafa Salem Fahelelbom, Laurentiu Morusciag, Sigurd ElzProblem statement: Several studies on the synthesis of new nifedipine analogs have been carried out, but the literature reveled that no study on the synthesis and calcium channel blocking activity of the substituted ester with an amide (5-phenylcarbamoyl) moiety has been reported. Approach: Six new derivatives of m-nifedipine have been successfully synthesized by substituting an ester moiety with an amide … …American Journal of Applied Sciences, Vol. 8, Issue 4 · 18 Apr 2011 · 8,247 accessesView PDFCite
Research ArticleOpen accessIn the abstractSynthesis and Characterization of Organotin(IV) N-Benzyl-N-Isopropyldithiocarbamate Compounds: Cytotoxic Assay on Human Hepatocarcinoma Cells (HepG2)Normah Awang, Ibrahim Baba, Nor Syaidatul Akmal Mohd Yousof, Nurul Farahana KamaludinProblem statement: Several studies on organotin(IV) dithiocarbamate compounds have been carried out but not on the synthesis and characterization together with cytotoxic assay of organotin(IV) N-benzyl-N-isopropyldithiocarbamate compounds. Approach: Three new organotin(IV) compounds of type N-benzyl-N-isopropyldithiocarbamate have been successfully synthesized by direct reaction between secondary amine with organotin(IV) chloride using in situ method. All the compounds were characterized using elemental analysis, … …American Journal of Applied Sciences, Vol. 7, Issue 8 · 31 Aug 2010 · 8,092 accessesView PDFCite
Research ArticleOpen accessIn the abstractSynthesis and Characterization of Organotin(IV) Complexes Derived of 2-amino-5-nitrobenzoic Acid: In vitro Antibacterial Screening ActivityYip-Foo Win, Siang-Guan Teoh, M. R. Vikneswaran et al.Problem statement: Tremendous studies have been carried out on organotin(IV) complexes derivatives of carboxylate anions. However, the synthesis and characterization as well as the in vitro antibacterial screening activity of organotin(IV) carboxylate derived of 2-amino-5-nitrobenzoic acid have not been carried out. Approach: Organotin(IV) carboxylate complexes derivative of 2-amino-5-nitrobenzoic acid, 2-NH2-5-NO2-C6H3COOH have been successfully synthesized. The acid and complexes obtained were … …American Journal of Applied Sciences, Vol. 7, Issue 7 · 31 Jul 2010 · 8,797 accessesView PDFCite
Research ArticleOpen accessIn the abstractSynthesis and Characterization of Organotin(IV) Complexes Derived of 3-(Dimethylamino)benzoic Acid: Cytotoxic Assay on Human Liver Carcinoma Cells (HepG2)Yip-Foo Win, Siang-Guan Teoh, Tengku-Sifzizul Tengku-Muhammad et al.Problem statement: Many studies have been carried out on organotin(IV) complexes derivative of carboxylate anions. However, the synthesis and characterization as well as the cytotoxic assay of organotin(IV) carboxylate derived of 3-(dimethylamino)benzoic acid have not been studied. Approach: Organotin(IV) carboxylate complexes derivative of 3-(dimethylamino)benzoic acid, 3-[N(CH3)2]C6H4COOH have been successfully synthesized. Two types of diorganotin(IV) complexes, [{3-[N(CH3)2]C6H4COO(R)2Sn}2O]2 dimer (R = methyl … …American Journal of Applied Sciences, Vol. 7, Issue 3 · 31 Mar 2010 · 8,310 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effects of Crosslinker and Monomer to the Polymerization of Polymethacrylamide Gel Dosimeters by Direct and Indirect MethodsElias Saion, A. H. Shaari, M. Z.A. Rahman et al.Radiation-induced polymerization in Polymethacrylamide Gels (PMAAGs) potentially used for 3D dose verification in radiotherapy has been studied using both Raman spectroscopy and Nuclear Magnetic Resonance (NMR) method. The dosimeters are composed of aqueous Methacrylamide (MAA) monomer and N, N’ methyelene-bis-acrylamide (BIS) crosslinker at various concentrations from 2 to 6% (w/w) and gelatin at 6% (w/w). The dosimeters were irradiated to … …American Journal of Applied Sciences, Vol. 2, Issue 8 · 31 Aug 2005 · 7,168 accessesView PDFCite