Research ArticleOpen accessIn the keywordsFollowing the Heart: The History of the J-Curve in Stroke RiskShoshana Reshef, Daniel ReshefReports of a J-shaped relationship between blood pressure and ischemic stroke are rare. The purpose of this study was to trace the published history of the J-curve theory as it relates to blood pressure, ischemic heart disease and eventually ischemic stroke. The J-curve publications on the relationship between Diastolic Blood Pressure (DBP) and ischemic stroke suggest that in certain populations, … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,356 accessesView PDFCite
Research ArticleOpen accessIn the abstractAge-Based Association of Glaucoma with the Prevalence of Diabetes and Hypertension at a National Hospital in SeoulSun Jung Lee, Tae Su Jang, Jae Kyung KimGlaucoma can have profound consequences on vision. Although diabetes and hypertension have been suggested as risk factors for glaucoma, their relevance in epidemiological studies remains controversial. Accordingly, we investigated whether diabetes and hypertension, as well as factors such as age and sex, affected the risk of glaucoma. From May 30, 2022, to June 24, 2022, 1152 patients were selected from … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 2 · 5 May 2023 · 5,263 accessesView PDFCite
Research ArticleOpen accessIn the abstractOrlistat Induce Renal Toxicity, DNA Damage, and Apoptosis in Normal and Obese Female RatsHaneen Mushtaq Hameed, Ahmed Flayyih Hasan, Zainab Haytham Razooki et al.Obesity has been linked to several chronic diseases, including fatty liver disease, fatty heart disease, diabetes mellitus, hypertension, obstructive sleep apnea, and cancer. The purpose of the current study was to determine how Orlistat affected renal toxicity, DNA damage, and apoptosis that were brought on by obesity in normal and obese female rats. There were four groups made up of … …OnLine Journal of Biological Sciences, Vol. 23, Issue 1 · 18 Jan 2023 · 5,831 accessesView PDFCite
Case ReportOpen accessIn the abstractIdentification and Management Implications of Fusobacterium Nucleatum PylephlebitisShoja Rahimian, Maria Labra, Ian Garrahy et al.Suppurativethrombophlebitis of the portal vein, or pylephlebitis, is a rare infectious manifestation. Only few casesresulting from Fusobacterium species have been reported, demonstratingthe disease that is in some ways analogous to Lemierre’s syndrome, orsuppurative thrombophlebitis of the internal jugular vein. Of these, Fusobacteriumnucleatum represents an important subtype with unique colon cancer risk.With high mortality rates up to 32% being described in … …American Journal of Infectious Diseases, Vol. 18, Issue 3 · 26 Sep 2022 · 5,689 accessesView PDFCite
Review ArticleOpen accessIn the abstractAntihypertensive Effects of Brazilian FruitsAugusto Altoé Puppin, Christiane Mileib Vasconcelos, Mirian de Almeida Silva et al.Cardiovascular disease is a health problem that generates economic and social impacts worldwide and hypertension is a major risk factor for the development of cardiovascular disease. Currently, conventional medicine offers treatments that control and regulate blood pressure through medication, but the traditional medicines of different cultures have used plants and foods to treat and prevent this type of disease for … …OnLine Journal of Biological Sciences, Vol. 20, Issue 2 · 19 Jun 2020 · 7,187 accessesView PDFCite
Research ArticleOpen accessIn the abstractRISK-BENEFIT ANALYSIS AND RISK MINIMIZATION OF QUINAPRIL: A REVIEWAnjo Sunny, M. Arif Khan, Darpelly Mahesh et al.The purpose of this review is to give the readers an insight about the risks and benefits of ’quinapril’, a potent Angiotensin Converting Enzyme Inhibitor (ACEI). Quinapril is a highly effective novel drug indicated for treatment of congestive heart failure and hypertension. Despite of the fact that safety profile is quite well with low incidence of adverse effects, an attempt … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 12 Feb 2014 · 7,254 accessesView PDFCite
Research ArticleOpen accessIn the abstractElevated Th17 and IL-23 in Hypertensive Patients with Acutly Increased Blood PressureJunxian Wang, Jianying Chen, Can Chen et al.Problem statement: Many severe cardiovascular complications such as stroke and heart attack can result from acutely increased blood pressure in patients with hypertension. The underlying mechanisms remain unclear despite of extensive study. To characterize the inflammatory mechanisms in hypertensive patients with acute blood pressure increase, we tested circulating Th17 levels, IL-23R expression and plasma levels of IL-17 and IL-23 in … …American Journal of Immunology, Vol. 8, Issue 2 · 21 May 2012 · 7,911 accessesView PDFCite
Research ArticleOpen accessIn the abstractNutrient and the Mind-Body Axis, in Relation to Omega-3 Fatty Acids and Amino AcidsToru Takahashi, Eri Toda, Ram B. Singh et al.Noncommunicable Diseases (NCDs); obesity, type 2 diabetes mellitus, Cardiovascular Diseases (CVDs) and cancer have become major health problems in both developing and developed countries. Physical inactivity and increased intake of energy rich proinflammatory foods in association with genetic predisposition are common primary risk factors for these problems. Mind-body interactions and mechanisms in relation to hypothalamus neurotransmitters and vagus nerve have … …Current Research in Medicine, Vol. 3, Issue 1 · 17 Feb 2012 · 7,322 accessesView PDFCite
Research ArticleOpen accessIn the abstractRandomized Clinical Stroke Trials in 2009Meheroz H. RabadiProblem statement: Stroke ranks as the leading cause of serious, long-term disability and death world-wide. It is estimated direct and indirect cost of stroke for 2009 was $68.9 billion. Approach: The objective of this review was to examine the effectiveness of emerging pharmacotherapy’s in patients with acute (≤2 weeks), sub-acute (2-12 weeks) and chronic (≥12 weeks) stroke studied in Randomized … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 7,243 accessesView PDFCite