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Research ArticleOpen accessFollowing the Heart: The History of the J-Curve in Stroke RiskShoshana Reshef, Daniel ReshefReports of a J-shaped relationship between blood pressure and ischemic stroke are rare. The purpose of this study was to trace the published history of the J-curve theory as it relates to blood pressure, ischemic heart disease and eventually ischemic stroke. The J-curve publications on the relationship between Diastolic Blood Pressure (DBP) and ischemic stroke suggest that in certain populations, … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,356 accessesView PDF Cite