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115 results for “drug research”
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Research ArticleOpen accessEvery word in the titleDrug-Protein Interactions for Clinical Research by Nucleic Acid Programmable Protein Arrays-Quartz Crystal Microbalance with Dissipation Factor Monitoring Nanoconductometric AssayClaudio Nicolini, Rosanna Spera, Nicola Luigi Bragazzi, Eugenia PechkovaConductometric monitoring of drug-gene and drug-protein interactions is of fundamental importance in the field of molecular pharmacology. Here, we present our main findings and characterizations of an important antiblastic used in neuro-oncology (Temozolomide), interacting with selected proteins that represent predictive biomarkers of the rate survival of the patients, of the outcome of chemotherapy and resistance to drug itself (namely, BRIP1 … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 3 · 17 Nov 2014 · 8,506 accessesView PDFCite
Research ArticleOpen accessIn the keywordsKinetic Optimization of Folic Acid Polymer Conjugates for Drug TargetingJacob M. Ngoy, Sunny E. Iyuke, Clarence S. Yah, Wilhelm E. NeuseProblem statement: Folic Acid (FA) is an essential, bioavailable water soluble B-complex vitamin that helps in the replication of normal cells. It is obtained from natural sources and it deficiency can leads to oncogenic cells development. Within this frame work in mind, we designed and synthesized a new bioconjugate carrier that can enhance the effectiveness of FA. Approach: The polymeric … …American Journal of Applied Sciences, Vol. 8, Issue 6 · 13 Jun 2011 · 7,101 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessing the Gender Dimensions of Drug Abuse Among Women and Girls in Maiduguri: Challenges and ImplicationsFredrick WilsonThis study examines the gender-specific dimensions of drug abuse among women and girls in Maiduguri, North East Nigeria, a region affected by insurgency, poverty, and restrictive socio-cultural norms. While national data indicate rising female substance use, interventions and research have largely overlooked women’s unique challenges. Drawing on in-depth interviews and focus group discussions, the study explores structural, emotional, and socio-cultural … …Journal of Social Sciences, Vol. 22, Issue 1 · 7 Sep 2026 · 801 accessesView PDFCite
Research ArticleOpen accessIn the abstractDeep Learning Analysis of Drug Reviews: Identifying Patient Conditions, Predicting Drug Ratings, and Sentiment AnalysisRafat Hammad, Mohammad Ashraf Ottom, Ayah Bani BakerUnderstanding patients' experiences with medications is essential for improving drug effectiveness, detecting potential side effects, and enhancing overall patient satisfaction. This research investigates applying machine learning to patient drug reviews across three main tasks: Identifying patient conditions, predicting drug ratings, and performing sentiment analysis. We implemented and evaluated Convolutional Neural Networks (CNNs), Artificial Neural Networks (ANNs), and Recurrent Neural Networks … …Journal of Computer Science, Vol. 22, Issue 9 · 7 Sep 2026 · 736 accessesView PDFCite