4 articles for “coronary flow”

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Research ArticleOpen accessEvery word in the titleEffect of Stent Geometry on Phase Shift between Pressure and Flow Waveforms in Stented Human Coronary ArteryVahab Dehlaghi, Siamak Najarian, Mohammad Tafazzoli ShadpourShear stress is known to play a central role in restenosis formation and is sensitive to stent geometry. Alterations of the phase shift between pressure and flow waveform created by a different stents were studied to compare the hemodynamic effects of stent design properties on restenosis in stented human coronary artery. Blood pressure waveforms were computed in three different sites, … …American Journal of Applied Sciences, Vol. 5, Issue 4 · 30 Apr 2008 · 7,252 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleNumerical Analysis of Pulsatile Blood Flow in a Stented Human Coronary Artery with a Flow DividerVahab Dehlaghi, Mohammad Tafazoli Shadpoor, Siamak NajarianShear stress is known to play a central role in restenosis formation and is sensitive to stent geometry. Local flow alterations created by a different stents without and with flow divider were studied to compare the hemodynamic effects of Stent design properties on restenosis in stented human coronary artery. Blood pressure and shear stress values were computed in three different … …American Journal of Applied Sciences, Vol. 4, Issue 6 · 30 Jun 2007 · 6,521 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsPalmitate-Induced Translocation of Caveolin-3 and Endothelial Nitric Oxide Synthase in CardiomyocytesCatherine J. Knowles, Megan Dionne, Martina Cebova, Ilka M. PinzProblem statement: Palmitate is a known cardiac lipotoxin that blunts cardiomyocyte contractile function and induces apoptosis, likely via accumulation of the lipotoxic ceramide. Ceramide is a sphingolipid and localizes to caveolae, which are lined in the inner membrane leaflet by caveolin proteins. In this study, we investigated the effects of palmitate on caveolin proteins and on endothelial Nitric Oxide Synthase … …OnLine Journal of Biological Sciences, Vol. 11, Issue 2 · 27 Aug 2011 · 7,894 accessesView PDF Cite

Research ArticleOpen accessIn the abstractWall Shear Stress Distribution in Patient Specific Coronary Artery BifurcationVahab Dehlaghi, Frank GijsenProblem statement: Atherogenesis is affected by hemodynamic parameters, such as wall shear stress and wall shear stress spatial gradient. These parameters are largely dependent on the geometry of arterial tree. Arterial bifurcations contain significant flow disturbances. Approach: The effects of branch angle and vessel diameter ratio at the bifurcations on the wall shear stress distribution in the coronary arterial tree … …American Journal of Applied Sciences, Vol. 7, Issue 9 · 30 Sep 2010 · 7,365 accessesView PDF Cite