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7 results for “carbapenems”

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Research ArticleOpen accessEvery word in the titlePharmacodynamic Comparison of the Carbapenems Against E. coli and Klebsiella spp. Containing Extended spectrum β-lactamasesKathryn J. Eagye, Joseph L. Kuti, David P. NicolauCarbapenems are the treatment of choice for extended-spectrum β-lactamases (ESBLs). Ertapenem is a new member of the carbapenem class, and is often grouped with imipenem and meropenem as a recommended treatment for ESBLs. However, new in vitro data question ertapenem’s inclusion as a first line treatment for these bacteria, suggesting that ertapenem has a lower likelihood of obtaining appropriate pharmacodynamic … …American Journal of Infectious Diseases, Vol. 1, Issue 3 · 30 Sep 2005 · 6,886 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAntibiotic Sensitivity Pattern of Blood Isolates of Acinetobacter Species in a Tertiary Care Hospital: A Retrospective AnalysisP. S. Shareek, D. Sureshkumar, Ramgopalakrishnan et al.Problem statement: Multi-drug resistant Acinetobacter bacterium is one of the major causes of sepsis in ICUs in tertiary care hospitals in India. In this report we describe the antibiotic sensitivity patterns of Acinetobacter species isolated from blood over a one year period at a tertiary care hospital. Approach: We retrospectively analyzed the sensitivity pattern of Acinetobacter species isolated from blood … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 24 Mar 2012 · 8,564 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Multiplex PCR Panel on Reducing Broad-Spectrum Antibiotic Use in Ventilator-Associated PneumoniaMaría Inés Staneloni, Emilio F. Huaier Arriazu et al.The extended use of broad-spectrum antimicrobials contribute to the growing threat of antimicrobial resistance. This study evaluated the impact of a multimodal strategy aiming at reducing the duration of broad-spectrum antimicrobial therapy in Ventilator-Associated Pneumonia (VAP). Conducted in a single Intensive Care Unit (ICU), this quasi-experimental, retrospective study compares a pre-intervention period (08/01/2018-07/01/2019) with an intervention period (08/01/2022-07/01/2023). Adult patients … …American Journal of Infectious Diseases, Vol. 21, Issue 1 · 8 Jul 2025 · 6,582 accessesView PDFCite
Research ArticleOpen accessIn the abstractBacterial Resistance in Primary Bloodstream Infections in the COVID-19 Pandemic: What has Changed at a Reference Hospital in Northeastern Brazil?Jonathan Da Silva Xavier, Jorge Luiz Nobre Rodrigues, Caroline Mary Gurgel Dias Florêncio et al.The increased use of central venous catheters due to the severity of COVID-19 cases and the difficulty in implementing preventive Healthcare-Associated Infection measures contributed to worsening an already challenging scenario of bacterial resistance. Characterizing the impact of these significant health crises on the bacterial resistance profile is necessary to strengthen antimicrobial control protocols in an effort to decrease morbidity. Our … …American Journal of Infectious Diseases, Vol. 20, Issue 2 · 4 Sep 2024 · 5,033 accessesView PDFCite
Review ArticleOpen accessIn the abstractAntimicrobial Resistance Pattern of Pseudomonas aeruginosa from Different Clinical Specimens: Survey ArticleHosniyeh E. Ladadweh, Hiba H. Falana, Jannat M. Ma’ali et al.Pseudomonas aeruginosa (P.A.) is a gram-negative, aerobic rod bacterium that mainly grows in soil and watery environments, infrequently being a part of microflora in healthy individuals. Since P.A. favors the growth in moistened areas, it can colonize in any simple aqueous solution, which in turn raises the risk of contamination and infection in hospital settings. The emergence of drug resistant … …American Journal of Pharmacology and Toxicology, Vol. 16, Issue 1 · 11 Jan 2021 · 8,396 accessesView PDFCite
Research ArticleOpen accessIn the abstractFrequency of Carbapenem Resistance among Gram Negative Pathogens in a Tertiary Care Hospital in Southern PakistanWaseela Ashraf, Altaf AhmedCarbapenems are considered the treatment of choice for treating the multi-drug resistance Gram negative bacteria. But resistance to these antibiotics has increased worldwide thus limiting therapeutic options for clinicians. To investigate the frequency and Minimum Inhibitory Concentrations (MICs) of carbapenem resistance in Gram negative organisms at a tertiary care hospital in Southern Pakistan. Seven Hundred and ninety-three carbapenem resistant isolates … …American Journal of Infectious Diseases, Vol. 11, Issue 4 · 29 Oct 2015 · 7,573 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Antimicrobial Stewardship Programme on Carbapenem Resistance in Gram Negative Isolates in an Indian Tertiary Care HospitalNamita Jaggi, Pushpa Sissodia, Lalit SharmaProblem statement: Increasing Antimicrobial resistance in the World is constantly becoming a Global threat and there is an urgent need to prevent its spread. Various studies of last decade have shown reduced trends of antimicrobial resistance in the pathogens as an outcome of the Antimicrobial Stewardship Programs. In view of this, the present four years’ study was carried out to … …American Journal of Infectious Diseases, Vol. 8, Issue 2 · 2 Oct 2012 · 7,626 accessesView PDFCite