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7 results for “calcium channel”

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Research ArticleOpen accessPhrase in the titleSynthesis and Calcium Channel Blocking Activity of 1, 4-Dihydropyridine Derivatives Containing Ester Substitute and Phenyl Carbamoyl GroupBassem Sadek, Khairi Mustafa Salem Fahelelbom, Laurentiu Morusciag, Sigurd ElzProblem statement: Several studies on the synthesis of new nifedipine analogs have been carried out, but the literature reveled that no study on the synthesis and calcium channel blocking activity of the substituted ester with an amide (5-phenylcarbamoyl) moiety has been reported. Approach: Six new derivatives of m-nifedipine have been successfully synthesized by substituting an ester moiety with an amide … …American Journal of Applied Sciences, Vol. 8, Issue 4 · 18 Apr 2011 · 8,247 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Research ArticleOpen accessIn the abstractAbout the Internal Structure of a Bone and its Functional RoleAntonio Apicella, Raffaella Aversa, Francesco Tamburrino, Florian Ion Tiberiu PetrescuThe human skeleton has the primary role of supporting all the organs that make up the body and at the same time to protect them permanently. It is made up so that it can hold and hold together all internal human organs, protecting them permanently, but also allowing them to move and exercise all their functionalities. This paper wants to … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 2 · 26 May 2018 · 8,402 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrescription Pattern of Anti-Hypertensive Drugs in Adherence to JNC- 7 GuidelinesKrishna Murti, M. Arif Khan, Akalanka Dey et al.The main objective of the present study to investigate the utilization pattern of antihypertensive drugs in hypertensive patients and to find out whether the prescription pattern is in adherence with the JNC7 guidelines for the management of hypertension. A prospective study was conducted and drug utilization data were collected from 137 hypertensive patients who were attended as Out Patient Department … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 1 · 2 Jun 2015 · 8,273 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Nifedipine on Dichlorvos-Induced Seizure in MiceKhayatnouri MirhadiProblem statement: Dichlorvos a synthetic organophosphate poisons is the property of insecticide. These toxins as insecticides in agriculture and medicine for animals and the destruction of ectoparasites can be used. Studies have shown that Dichlorvos creation seizure effects in different animals. Nifedipine, dihydropyridine calcium channel blockers, widely used for treatment of cardiovascular diseases. Studies have shown that the calcium channel … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 2 · 17 Sep 2011 · 8,054 accessesView PDFCite
Research ArticleOpen accessIn the abstractVoltage-Gated Channels as Causative Agents for EpilepsiesMutasem Abuhamed, Xiao Bo, Kun Xia et al.Problem statement: Epilepsy is a common neurological disorder that afflicts 1-2% of the general population worldwide. It encompasses a variety of disorders with seizures. Approach: Idiopathic epilepsies were defined as a heterogeneous group of seizure disorders that show no underlying cause .Voltage-gated ion channels defect were recognized etiology of epilepsy in the central nervous system. The aim of this article … …American Journal of Immunology, Vol. 4, Issue 4 · 31 Dec 2008 · 6,959 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeural Network in Modeling Malaysian Oil Palm YieldZuhaimy Ismail, Azme KhamisProblem statement: Forecasting of palm oil yield has become an important element in the management of oil palm industry for proper planning and decision making. The importance of yield forecasting has led us to explore modeling of palm oil yield for Malaysia using the most recent development of Artificial Neural Network (ANN). The main issue in yield forecasting is to … …American Journal of Applied Sciences, Vol. 8, Issue 8 · 19 Jul 2011 · 8,576 accessesView PDFCite