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17 results for “antioxidant therapy”
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Research ArticleOpen accessIn the keywordsProtective Effect of Enicostemma littorale Blume Methanolic Extract on Gentamicin-Induced Nephrotoxicity in RatsNiraj Mukundray Bhatt, Kinjal Chauhan, Sharad Gupta et al.Problem statement: The Amino glycoside antibiotics cause drug induced nephrotoxicity at therapeutic doses and thus limits the use clinically. Oxidative stress is one of the main reasons for the development of nephrotoxicity. Approach: In light of this the aim of the present study was to investigate the role of mitochondrial as well as post-mitochondrial oxidative stress in the development of … …American Journal of Infectious Diseases, Vol. 7, Issue 4 · 30 Nov 2011 · 9,547 accessesView PDFCite
Research ArticleOpen accessIn the keywordsLaser Therapy of Irradiated Traumatized Skeletal Muscles and State of Immune System in AnimalsNelly Bulyakova, Svetlana Zubkova, Valentina AzarovaProblems statement: This study was designed to examine the effect of laser therapy on regeneration of traumatized skeletal muscles and on dynamics of immune responses in thymus and bone marrow under ionizing radiation. Approach: After local X-ray radiation of both rat gastrocnemius muscles at a dose 20 Gy or after total γ-irradiation of animals at a semiletal dose 6 Gy, … …OnLine Journal of Biological Sciences, Vol. 11, Issue 2 · 27 Aug 2011 · 8,198 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Effect of Lactoferrin against Chromium Induced Adverse Renal Changes in Rats: Oxidative Stress TheoryMohammed H. Hassan, Dorreia Abd-Alla Mohamed Zaghloul, Marwa Ahmed Mahmoud et al.Among the toxic metals, chromium (Cr) which is a naturally occurring heavy metal commonly enters the environment through the effluents from various industries. Kidney disease is often cited as an adverse effect of chromium. We aimed to assess chromium-induced pathophysiological adverse renal damage and determine the potential protective effects of co-therapy with Lactoferrin (LF) in male albino rats. Forty male … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 2 · 28 Apr 2021 · 6,663 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntidiabetic and Antioxidant Potential of Vernonia amygdalina Leaf Extract in Alloxan-Induced Sprague-Dawley RatsFatmawaty Yazid, Nina Bonita Hasanah, Rosmalena et al.The treatment of diabetes mellitus using drug medications have side effects such as weight gain, hypoglycemia, the risk of cardiovascular or all-cause mortality. These limitations have become one reason to use complementary therapy from plant extract, such as Vernonia amygdalina as an antidiabetes. This research aimed to investigate the effect of V. amygdalina leaf extracts as antidiabetic and antioxidant agents … …OnLine Journal of Biological Sciences, Vol. 20, Issue 4 · 23 Nov 2020 · 8,649 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Euphorbia helioscopia Extract Administration on Diabetes Induced by Alloxan in MiceDoha Mohammad Beltagy, Amira Mohammed Beltagy, Mohammad Ramadan et al.Diabetes describes metabolic disorder with hyperglycemia and neurotic changes. This work aimed to evaluate the protective effect of total ethanolic extract of Euphorbia helioscopia grown in Egypt against pancreas and brain injuries in diabetic mice induced by alloxan. This work was carried out on 60 mice divided into four groups. Control Group (G1) included healthy normal mice that did not … …OnLine Journal of Biological Sciences, Vol. 20, Issue 3 · 19 Oct 2020 · 6,406 accessesView PDFCite
Research ArticleOpen accessIn the abstractSynthesis, Ant Proliferative Activity and Docking Study of New Quercetin Derivatives against MDA-MB231 Breast Cancer Cell LinesReham Adnan Al-Anssari, Rita S. Elias, Shaker A.N. AljadaanMDA-MB231 is a very aggressive and invasive triple negative breast cancer, which present with limited treatment options. Unlike other breast cancer types, it is characterized by absence of hormonal receptors of estrogen, progesterone as well as human epidermal growth factor receptor 2, rendering it unsuitable for hormonal therapy and a perfect candidate for chemotherapy. Quercetin is a common natural flavonoid … …American Journal of Applied Sciences, Vol. 16, Issue 5 · 26 Jun 2019 · 8,790 accessesView PDFCite
InvestigationOpen accessIn the abstractRegularities of the Oxidative Stress Processes in Case of Bleedings from Acute and Chronic Ulcers of the Stomach and DuodenumEkaterina Vladimirovna Silina, Mukimdjon Ahmadzhonovich Sobirovz, Sergey Brankovich Bolevich, Victor Aleksandrovich StupinThe main aim of the study was to determine ways of improving the results of treating patients with ulcer bleeding of various nature and severity. It was provided by the system study of free radical processes and evaluation of the effectiveness of timely antioxidant therapy. Material and methods. The study included 153 patients aged 18-94 years with acute and chronic … …OnLine Journal of Biological Sciences, Vol. 18, Issue 2 · 4 May 2018 · 7,416 accessesView PDFCite
Research ArticleOpen accessIn the abstractAMELIORATIVE EFFECT OF HIBISCUS SABDARIFFA LINN ON SUBCHRONIC CHLORPYRIFOS-INDUCED ALTERATIONS IN SEX AND THYROID HORMONES IN MALE WISTAR RATSShittu Muftau, Olatunji Omobolanle Aisha, Suleiman Folorunsho Ambali et al.Studies have shown that Chlorpyrifos (CPF), an Organophosphate (OP) insecticide alters both sex and thyroid hormones. Apart from inhibiting Acetylcholinesterase (AChE) activity, CPF has been shown to cause oxidative stress. The antioxidant potentials of many flavonoid-containing plants are increasingly being exploited in the therapy of many infectious and non-infectious diseases. Hibiscus Sabdariffa (HS) is one of the most widely used … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 20 Feb 2014 · 9,097 accessesView PDFCite
Research ArticleOpen accessIn the abstractQUERCETIN AMELIORATES DIABETIC NEPHROPATHY IN RATS VIA MODULATION OF RENAL NA+, K+-ATPASE EXPRESSION AND OXIDATIVE STRESSSalah O. Bashir, Mohamed Darwesh Morsy, Hussein F. Sakr et al.Diabetic Nephropathy (DN) is one of most prevalent complications of Diabetes Mellitus (DM), therefore prevention of its development is a important field for researches. Quercetin is a plant flavenoid with hypoglycemic and antioxidant properties that is claimed to have a reno-protective effect in diabetes. This study was designed to investigate the reno-preventive role of Quercetin treatment in terms of biochemical … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 14 Feb 2014 · 8,047 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of New Compound with Antioxidant Potential in the Energy Metabolism of Adults Rats after Pneumococcal MeningitisT. Barichello, Geovana Dagostim Savi, A. P. Panatto et al.Problem statement: In bacterial meningitis, the Streptococcus pneumoniae can modify the cerebro-spinal fluid (CSF) homeostasis and initiation of the host inflammatory response with presence cytokine and leukocyte migration into the subarachnoidal space. Despite the availability of highly effective antibiotics, the disease is often fatal or causes long-term neurological problems in affected patients. Approach: The aim of this study was to … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 2 · 15 Jun 2012 · 7,788 accessesView PDFCite