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7 results for “anti-diabetic activity”

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Research ArticleOpen accessPhrase in the titleAnti-Diabetic Activity of a Fraction from Cissus verticillata and Tyramine, its Main Bioactive Constituent, in Alloxan-Induced Diabetic RatsCleide de Sousa Lino, Thiago de P. Sales, Patrícia B. Gomes et al.Cissus verticillata (syn. C. sycioides, fam. Vitaceae) is a medicinal plant popularly used in Brazil, for the treatment of diabetes mellitus. The anti-diabetic activity of a fraction from leaves of Cissus verticilllata (MSF, methanol soluble fraction), as well as that of tyramine (TYR) were investigated, in the model of alloxan-induced diabetes, in male Wistar rats. The biochemical parameters studied were: … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 4 · 31 Dec 2007 · 8,627 accessesView PDFCite
Research ArticleOpen accessIn the abstractWound Healing Activity of Chlorogenic Acid in Diabetic Rats is Mediated Through Antibacterial, Antioxidant, and Proliferative EffectsAbdullah Abdulrahman Al-Ghanayem, Mohammed Sanad Alhussaini, AbdulRahman Abdulla Ibrahim Alyahya et al.Chlorogenic acid is known to have antibacterial action against a number of pathogens. This study provides insights into the potentiality of chlorogenic acid in the treatment of chronic infection in wounds. The anti-infective and healing effect of chlorogenic acid in infected wounds was evaluated using diabetic rats. Antibacterial activity of chlorogenic acid against Methicillin-Resistant Staphylococcus Aureus (MRSA) and Multidrug-Resistant (MDR) … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 21 Jan 2024 · 6,154 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Oxidant and Enzyme-Inhibitory Potential of Marine StreptomycesT. Revathy, M. A. Jayasri, K. SuthindhiranMarine actinomycetes are potential source for the discovery of novel compounds and enzymes. Though extensive research on marine actinomycetes is underway globally, the actinomycetes research from Indian marine ecosystem is unexplored and understudied. Hence, the present research is focussed on the screening of bioactive compounds from marine actinomycetes isolated from Indian coastal region. This study is designed to determine the … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 7,239 accessesView PDFCite
Research ArticleOpen accessIn the abstractInfluence of Quercetin on Diabetes-Induced Alteration in CYP3A Activity and Bioavailability of Pioglitazone in RatsSudhir Niranjan Umathe, Pankaj Vinod Dixit, Jignesh Manubhai Vaghasiya, Nishant Sudhir JainProblem statement: Quercetin-a common bioflavonoid, is present in herbal preparations consumed by diabetic patients along with routine anti-diabetic agents. We recently showed that quercetin increases the bioavailability of pioglitazone in non-diabetic rats. Thus, present study investigated whether this pharmacokinetic interaction is also evident in diabetic animals, especially because diabetic subjects have altered gastrointestinal (GI) function and CYP3A activity. Approach: The … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,818 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Effect of Enicostemma littorale Blume on Rat Model of Diabetic NeuropathyNiraj Mukundray Bhatt, Suparna Barua, Sarita GuptaProblem statement: Poor glycemic control and oxidative stress is implicated as a common pathway in the development of diabetic neuropathy. Approach: In the present study, we investigated the protective effects of Enicostemma littorale Blume (EL) (2.5 g kg-1), a hypoglycemic and antioxidant herbal medicine in alloxan-induced diabetic neuropathy in male Charles foster rats. Results: Tail flick latency in hot immersion … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,838 accessesView PDFCite
Research ArticleOpen accessIn the abstractChaenomeles Sinensis: A Potent α-and β-Glucosidase InhibitorShruti Sancheti, Sandesh Sancheti, Sung-Yum SeoProblem statement: Glycosidase inhibitors are vital sources for the treatment of diabetes type II with a special importance in pharmacology, food industry and biotechnology, since for diabetes control, different diets and drugs, especially herbal medicines are recommended in this era. Approach: While screening for the potent natural glycosidase inhibitors, we found the fruits of Chaenomeles sinensis (C. sinensis), as the … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 1 · 31 Mar 2009 · 12,071 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordPhytochemical Profiles and Anti-Diabetic Potential of the Extract of Pueraria lobata Compound Teabags: Preparation and Optimization Infusion ConditionsQing Liu, Wenyue Shi, Futing Xue et al.A Pueraria lobata root compound teabag using Pueraria lobate root, Stigma maydis, and Prunus mume as the main material was prepared in this study, and the brewing technology was optimized using Response Surface Methodology (RSM). The sensory evaluation, total polysaccharide, and phenolic compound content were used as evaluation indicators and the effect of the compound ratio of raw material was … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 26 Nov 2022 · 5,641 accessesView PDFCite