Research ArticleOpen accessIn the keywordsSafety Assessment of Herbal Formulations, Rumbion™ and Tyrel™ in Albino Wistar RatsA.J. Joshua, K.S. Goudar, N. Sameera et al.Problem statement: Herbal remedies form one of the effective strategies for management of livestock healthcare. Despite the availability of extensive pharmacological information, the toxicological data on herbs and herbal preparations seem to be scanty. The objective of the present investigation was to evaluate the acute oral toxicity of some herbal veterinary preparations in albino Wistar rats. Approach: In the sighting … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 1 · 31 Mar 2010 · 8,544 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Research ArticleOpen accessIn the abstractAcute and Subchronic Toxicity of Mulberry FruitsJintanaporn Wattanathorn, Wipawee Thukummee, Cholathip Thipkaew et al.At present, the application of phytomedicine worldwide is substantial increase. The data of the acute and subchronic toxicity studies on medicinal plants or fruits and vegetables used for medicinal purposes should be obtained in order to increase the confidence in its safety to human, particularly for the application as functional food. Despite the widely consumption of mulberry (Morus alba L, … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 3 · 19 Sep 2012 · 33,868 accessesView PDFCite
Research ArticleOpen accessIn the abstractToxicological Evaluation of Murraya Paniculata (L.) Leaves Extract on RodentsR. K. Goel, C. V. Rao, A. Singh, M. K. GautamProblem statement: Present study was aimed to explore the acute and sub-acute toxicities studies with orally administered 50% ethanolic leaves extract of Murraya paniculata. Approach: Acute toxicity (oral single dose, 50-2000 mg kg-1) includes any mortality and CNS and ANS toxicities in mice while, sub-acute toxicity (100, 200 and 400 mg kg-1, orally and once daily for 28 days) includes … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 2 · 9 Jul 2012 · 8,076 accessesView PDFCite
Research ArticleOpen accessIn the abstractUsing Bioequivalence Approach to Assess Toxicity Effect of Herbal Products, TyrelTM and RumbionTMChunhao Tu, Woon Yuen KohProblem statement: Herbal products have been widely used in veterinary healthcare. Recently, an experiment was conducted in the Natural Animal Facility Pvt. Ltd., Bangalore, India on ten Albino Wistar female mice to assess the acute oral toxicity of two herbal products, TyrelTM and RumbionTM. However, the researchers did not evaluate the toxicity effect of the two products in terms of … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 7,823 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Inflammatory Activity of Vitex leucoxylon L. Bark Extracts Against Freund's Complete Adjuvant Induced Arthritis in Sprague Dawley RatAlluri V. Krishnaraju, Chundi B.M. Rao, Dodda Sundararaju et al.Problem statement: Anti-inflammatory agents, particularly steroids and cyclooxygenase inhibitors are often associated with adverse side effects including, GI irritation, ulcers, hypertension and cardiac abnormalities. A safe and effective intervention is essential for the treatment of inflammatory disorders. Approach: Abstract Vitex leucoxylon L., a medicinal plant of the verbenaceae family, used in traditional medicine for relieving headache and catarrh. VL-89/185A, was … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 8,044 accessesView PDFCite
Research ArticleOpen accessIn the abstractStability of Neodymium(III) Complexes of 4-Hydroxycoumarins with Anticoagulant ActivityIrena Kostova, Irina NikolovaComplexes of neodymium(III) with 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one, 4-hydroxy-3-[1-(4-chlorophenyl)-3-oxobutyl]-2H-1-benzopyran-2-one and 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-1-benzopyran-2-one were synthesized by mixing of water solutions of neodymium(III) nitrate and the respective ligands, in amounts equal to metal: ligand molar ratio of 1: 3. The complexes were characterized and identified by elemental analysis, conductivity, IR and 1H NMR spectral data. DTA and TGA have been applied to confirm the compositions of … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 2 · 30 Jun 2006 · 7,554 accessesView PDFCite
Case ReportOpen accessAll words, across the recordSurvival Following Severe Paraquat Poisoning a Case Study from the Andaman and Nicobar IslandsShiv Shankar Singh, Colin Sanchez, Prasan Kumar PandaParaquat poisoning continues to pose a significant public health challenge in the Andaman and Nicobar Islands, largely due to its alarmingly high mortality rate. In this report, we present the case of a 39-year-old male farmer who ingested 30 mL of paraquat with the intent of suicide. Initially, the patient underwent prompt gastric lavage and exhibited relative stability. Upon admission, … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 22 Jan 2025 · 10,605 accessesView PDFCite