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195 results for “able gene”
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Research ArticleOpen accessIn the abstractIsolation and Characterization of Superior Symbiotic Bacterial Isolates from the Oenggae Sea with Potential as AntibacterialLukas Pardosi, Adelya Irawan Manalu, Charles Venirius LisnahanSponges are one of the marine biota that have a symbiotic relationship with bacteria which can produce secondary metabolites as antimicrobials. The main aim of this research was to isolate and identify bacteria that had potential as antibacterials against multi-drug resistant test bacteria. The sponsor samples used in this research were Stylissa massa, Salvador Dali, and Angelas sp. The methods … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 26 Mar 2024 · 5,057 accessesView PDFCite
Research ArticleOpen accessIn the abstractSequence Analysis of Scaffold/Matrix Attachment Regions (S/MARs) From Human Embryonic Kidney and Chinese Hamster Ovary CellsNur Shazwani Mohd Pilus, Azrin Ahmad, Nurul Yuziana Mohd YusofBinding of intergenic Scaffold/Matrix Attachment Regions (S/MARs) to nuclear matrix proteins is believed to poise adjacent genes for transcription by forming chromatin loops. Vector constructs containing Scaffold/Matrix Attachment Regions (S/MAR) flanking the gene of interest, therefore, are able to enhance recombinant protein expression in mammalian cells. We compared two methods that are based on buffers containing 2M NaCl and Lithium-3,5-diidosalicylate … …OnLine Journal of Biological Sciences, Vol. 18, Issue 4 · 8 Oct 2018 · 7,637 accessesView PDFCite
Research ArticleOpen accessIn the abstractSequence Analysis of VP2 Gene of the Parvoviruses Isolated from Fecal Samples of Domestic Cats in Tehran, IranNegin Jahanbin, Shahram Jamshidi, Omid MadadgarPanleukopenia is a viral enteritis of high mortality rate in Feline population. It is caused by a small single-stranded DNA virus, belonging to the Family Parvoviridae, called Feline Panleukopenia Virus (FPV). Parvoviruses are capable of adapting to new hosts and can simply mutate like RNA viruses, resulting in the emergence of different strains with antigenic changes. Unlike the original Canine … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 4 · 28 Oct 2017 · 7,696 accessesView PDFCite
EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,285 accessesView PDFCite
EditorialOpen accessIn the abstractAn Opportunity for the Agricultural Sector: The Renewable Energy SourcesRiccardo Testa, Salvatore TudiscaToday, among the most important issue for energy decisions by policymakers, there are security challenges and environmental impacts on climate change and economic aspects. Since the seventies, in fact, global warming and environmental issues have had an increasing importance in international debate, attracting the attention of several scientific studies (Landi and Benelli, 2016). Many of these studies denoted that over … …American Journal of Agricultural and Biological Sciences, Vol. 11, Issue 3 · 6 Sep 2016 · 8,098 accessesView PDFCite
EditorialOpen accessIn the abstractAre we Able to Harness the Immunomodulatory Power of Cytokines for Novel Autoimmune Disease Treatments?Giuseppe Nocentini, Graziella Migliorati, Carlo RiccardiSince the end of the 1970s, interleukin 2 (IL-2) has been known as a key player in T cell expansion/activation (Watson et al., 1980). In the late 1980s, some groups used IL-2 to stimulate the immune systems of tumour patients (Jacobs et al., 1986). The idea seemed brilliant and several attempts were made, but the results were disappointing (Lim et … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 2 · 22 Oct 2015 · 7,629 accessesView PDFCite
EditorialOpen accessIn the abstractNeutrophil Extracellular Traps as Therapeutic Targets for Inflammatory DiseaseRory R. KoenenNeutrophilic granulocytes, or neutrophils are the most abundant circulating white blood cell and constitute a first line of defense against pathogens. They are characterized by a large polymorphic lobular nucleus and the presence of many secretory granules in their cytoplasm. Neutrophils are essential for a functional host defense, as is evidenced by the occurrence of severe infections in individuals with … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 25 Feb 2015 · 8,740 accessesView PDFCite
Research ArticleOpen accessIn the abstractDrug-Protein Interactions for Clinical Research by Nucleic Acid Programmable Protein Arrays-Quartz Crystal Microbalance with Dissipation Factor Monitoring Nanoconductometric AssayClaudio Nicolini, Rosanna Spera, Nicola Luigi Bragazzi, Eugenia PechkovaConductometric monitoring of drug-gene and drug-protein interactions is of fundamental importance in the field of molecular pharmacology. Here, we present our main findings and characterizations of an important antiblastic used in neuro-oncology (Temozolomide), interacting with selected proteins that represent predictive biomarkers of the rate survival of the patients, of the outcome of chemotherapy and resistance to drug itself (namely, BRIP1 … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 3 · 17 Nov 2014 · 8,510 accessesView PDFCite
EditorialOpen accessIn the abstractRECENT TRENDS AND CHALLENGES OF ENERGY EFFICIENT AND SUSTAINABLE BUILDINGSChiara BedonAccording to several studies (e.g., the Intergovernmental Panel on Climate Change (IPCC, 2014), the US Energy Information Administration (US EIA, 2014), warming of the climate system is unequivocal and mainly derives from greenhouse gas emissions due to human activities. Global Carbon Dioxide (CO2) emissions from fossil fuels, for example, are estimated to be 29% higher in 2035 than they were … …American Journal of Engineering and Applied Sciences, Vol. 7, Issue 3 · 11 Sep 2014 · 8,503 accessesView PDFCite
Research ArticleOpen accessIn the abstractEnhancement of Nutritional Quality of Wheat (Triticum aestivum) by Metabolic Engineering of Isoflavone PathwayAhmed Mohamed El-Shehawi, Abdelmegid Ibrahim Fahmi, Mona Mohamed Elseehy, Hesham Ahmed NagatyIsoflavones are large group of secondary metabolites produced in legumes such as soybeans. They have essential biological functions as nutraceutical and health functions for human. They are involved in plant resistance to biotic and abiotic stresses, symbiotic relationship with nitrogen-fixing organisms and plant competition (allelopathy). In this report, isoflavonoids were expressed in wheat (Triticum aestivum) via introducing the key enzymes … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 7,139 accessesView PDFCite