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Research ArticleOpen accessIn the keywordsIn Vivo Neutralization of Naja nigricollis Venom by Uvaria chamaeOmale James, Ebiloma Unekwuojo Godwin, Idoko Grace OtiniUvaria chamae is a well known medicinal plant in Nigerian traditional medicine for the management of many diseases, but investigations concerning its pharmacological characteristics are rare. In this study, we evaluate its venom neutralizing properties against Naja nigricollis venom in rats. Freshly collected Uvaria chamae leaves were air dried, powdered and extracted in methanol. To study the antivenom properties, albino … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 8,421 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAssay for Rapid Screening of Phytochemicals as Antimicrobial AgentsGhosh Saurav, Indranil Mukherjee, Ashoke Ranjan Thakur, Shaon Ray ChaudhuriThe present study aims to develop a rapid method for antibiotic sensitivity detection and screening of natural products for antimicrobial activity. The dimension of WBC in blood film was found to get altered when seeded with bacteria and monitored under light microscope. The shrinkage was prevented in response to antibiotic treatment and validated using statistical analysis (two sample one tailed … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 1 · 18 Mar 2013 · 8,303 accessesView PDFCite
Research ArticleOpen accessIn the keywordsErythropoietin-Like Effects of Dihydroartemisinin in Wistar Albino RatsUtoh-Nedosa Uchechukwu Anastasia, Nedosa Kenechi Stanislaus, Onyedibe Ikenna KennethArtemisinin drugs were active during the intra-erythrocytic stage of malaria parasite infection. The activity of artemisinin and synthetic endoperoxides was related to their interaction with heme. The electrophillic intermediate formed from artemisinin in the presence of heme alkylates the protein portion of hemoglobin preferentially to the heme portion. Problem statement: Since there might be an interaction between artemisinin and the … …American Journal of Agricultural and Biological Sciences, Vol. 6, Issue 4 · 9 Dec 2011 · 7,785 accessesView PDFCite
Research ArticleOpen accessIn the keywordsRule Extraction from Radial Basis Functional Neural Networks by Using Particle Swarm OptimizationM. R. Senapati, I. Vijaya, P. K. DashRadial basis functional neural networks (RBFNN) provide an outstanding possibility for generating rules for solving pattern classification problems. One of the most important factors in RBFNN is finding out the center and spread. This paper examines rules extracted from RBF networks trained by Particle swarm Optimization (PSO). The selection of the RBFNN centers, spreads and the network weights can be … …Journal of Computer Science, Vol. 3, Issue 8 · 31 Aug 2007 · 6,784 accessesView PDFCite
Research ArticleOpen accessIn the keywordsGastroprotective Effect and Safety Assessment of Zanthoxylum Zanthoxyloides (Lam) Waterm Root Bark ExtractAlex Boye, George Asumeng Koffuor, Johnson Nyarko Boampong et al.Problem statement: Gastrointestinal ulcers account significantly for morbidity and mortality in Ghana. The study therefore investigated the gastroprotective effect of an ethanolic root bark extract of Zanthoxylum zanthxyloides and its safety for us. Approach: Gastric ulceration was induced in Sprague-Dawley rats with Indomethacin (25 mg kg-1, p.o) and was treated with 150, 250, or 500 mg kg-1 of the extract, … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 2 · 7 Aug 2012 · 8,495 accessesView PDFCite
Research ArticleOpen accessIn the keywordsToxicological Evaluation of Murraya Paniculata (L.) Leaves Extract on RodentsR. K. Goel, C. V. Rao, A. Singh, M. K. GautamProblem statement: Present study was aimed to explore the acute and sub-acute toxicities studies with orally administered 50% ethanolic leaves extract of Murraya paniculata. Approach: Acute toxicity (oral single dose, 50-2000 mg kg-1) includes any mortality and CNS and ANS toxicities in mice while, sub-acute toxicity (100, 200 and 400 mg kg-1, orally and once daily for 28 days) includes … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 2 · 9 Jul 2012 · 8,076 accessesView PDFCite
Research ArticleOpen accessIn the keywordsExtra-Bone Marrow Sites of Haemopoeisis: Dihydroartemisinin Effects in Wistar Albino RatsNedosa Uchechukwu Anastasia, Saleh Mohammed, Nedosa Kenechi Stanislaus et al.Problem statement: Iron is present in ferritin, the storage form of iron in the tissues; in the respiratory cytochrome enzymes; in hemoglobin of the blood and in the myoglobin of muscle Dihydroartemisinin (DHA) has been shown to interact with heme groups in vivo and in vitro. This study investigated the effects of 5 day and 7day oral dihydroartemisinin treatments on … …American Journal of Applied Sciences, Vol. 9, Issue 1 · 2 Nov 2011 · 6,826 accessesView PDFCite
Research ArticleOpen accessIn the abstractHaemato-Biochemical Indices of Red Sokoto Goats Fed Various Levels of Earthworm Meal-Based DietsMoshood Adewale Belewu, Ling Shing Wong et al.Blood is essential to life and it is vital for the transportation of oxygen from the lungs to every cell of the body for metabolism purposes. Hence, blood samples were collected from thirty (30) healthy Red Sokoto goats fed an earthworm meal-based diet with ten goats per treatment constituting a replicate in a Completely Randomized design model to evaluate the … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 3 Dec 2024 · 4,963 accessesView PDFCite
Research ArticleOpen accessIn the abstractHematological and Biochemical Analysis of Asymptomatic Fascioliasis of Bali Cattle (Bos Javanicus)Maskur, Adji Santoso Drajat, Sulaiman Ngongu Depamede et al.The research was to examine the hematological characteristic of fascioliasis in Bali cattle in year-round irrigated rice fields in tropical areas. Fifty cattle raised in rice field areas were examined by hematology, coproscopy, physiology, and liver function tests. The results showed that 50 cattle had heartbeat, respiratory and rectal temperature in normal standard, but, 41 (82%) out of 50 cattle … …American Journal of Animal and Veterinary Sciences, Vol. 17, Issue 3 · 4 Aug 2022 · 6,205 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Slum Water on Physiology of Heteropneustes fossilis Collected from Silchar, AssamRubina Roy, Bijoy Brahma, Satabdi Bhattacharjee, Soumitra NathPoverty and overpopulation are not just prevailing in big cities, but have also become a matter of concern in small towns. Safe drinking water is considered a basic human need, yet millions of people do not have access to an adequate and safe water supply. The present study is focused on the quality assessment of water bodies of slum areas … …American Journal of Animal and Veterinary Sciences, Vol. 14, Issue 1 · 11 Feb 2019 · 7,912 accessesView PDFCite