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10 articles for “Vaccine Candidate”
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Literature ReviewOpen accessPhrase in the titleStaphylococcus aureus Vaccine Candidate from MRSA Isolates: The Prospect of a Multivalent VaccineNovra Arya Sandi, Tenri Ashari Wanahari, Isabel MacPhillamy et al.Staphylococcus aureus (S. aureus) is a major cause various infections in humans and animals throughout the world. The increasing incidence of S. aureus infection, particularly methicillin-resistant Staphylococcus aureus (MRSA) is complicated by the antibiotic-resistance phenomenon. Thus, it requires new strategies to prevent wider scale of its incidence occurring. Preventative methods against infectious diseases through vaccination can prevent, control and reduce … …American Journal of Infectious Diseases, Vol. 11, Issue 3 · 27 Aug 2015 · 8,471 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleDevelopment of Transgenic Maize using Immature Embryos of HiII Genotype as a Vaccine CandidateHyun A. Kim, Suk Yoon Kwon, Han Sang Yoo et al.Problem statement: Plant-based vaccines posses some advantages over other types of vaccine biotechnology such as safety, low cost of mass vaccination programs and wider use of vaccines for veterinary medicine. These study was undertaken to develop the transgenic maize as edible vaccine candidate for animals. Approach: The immature embryos of HiII genotype were inoculated with A. tumefaciens strain C58C1 containing … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 1 · 5 Mar 2012 · 7,567 accessesView PDFCite
Research ArticleOpen accessIn the keywordsProduction of Immunologically Active Untagged Recombinant DENV-2 NS1 in Escherichia coliDessy Natalia, Christian Heryakusuma, Fernita Puspasari et al.Dengue is an infectious disease affecting 390 millions people in tropical and subtropical region annually. Dengue virus NS1 protein plays an important role in viral replication in the host cell and it is detected in high level in the infected patient serum. A synthetic gene of untagged DENV-2 NS1 with codons optimization for expression in Escherichia coli has been generated … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 3 · 10 Oct 2018 · 10,346 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Characterization of Contagious Pustular Dermatitis Virus in Goats of Sri LankaSusanthaa Piratheepan, Sumathy Puvanendran, Kalyani PereraContagious Pustular Dermatitis (CPD), is a zoonotic disease of small ruminants causing severe deterioration of skin. Contagious Pustular Dermatitis Virus (CPDV) is an epitheliotrophic virus belonging to the parapox virus. Accurate information on CPD in Sri Lanka is scarce. This study was conducted to investigate the prevalence and to characterize the CPD virus from goats in Sri Lanka and select … …American Journal of Animal and Veterinary Sciences, Vol. 18, Issue 4 · 29 Nov 2023 · 5,346 accessesView PDFCite
Research ArticleOpen accessIn the abstractVirtual Screening of CPP Conjugated Peptide as QcrB BCC Protein Inhibitors of Mycobacterium tuberculosis BacteriaMuhammad Ihsan Muttaqin, Manaman Huang, Usman Sumo Friend TambunanTuberculosis is a global leading cause of death, just below COVID-19 and ranked above HIV. This disease is caused by a pathogen called Mycobacterium tuberculosis, which spreads easily through the air and is known to remain latent in most people's bodies, about a quarter of the world's population. The current problems with TB also include two main concerns: The official … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 14 Mar 2024 · 5,518 accessesView PDFCite
EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,281 accessesView PDFCite
Research ArticleOpen accessIn the abstractSDS-PAGE Protein Pattern and Antigenicity Cross Reaction of Human SchistosomesNahed A.A. EL-Ossily, Doaa A. Yones, Mohamed El-Salahy M.M. Monib et al.Schistosomiasis is one of the most important neglected tropical diseases. Its control depends on treatment with the available drug praziquantel. No vaccine exists despite the intense search for molecular candidates and adjuvant formulations over the last three decades. The present study aimed to compare the antigenic protein structures of Schistosoma mansoni, S. haematobium, Fasciola. hepatica and Echinococus granulosus hydatid cyst … …American Journal of Infectious Diseases, Vol. 12, Issue 1 · 10 Feb 2016 · 7,354 accessesView PDFCite
Research ArticleOpen accessIn the abstractTargeting Cellular Receptors as a Strategy for the Development of New Generation Mucosal VaccinesConstantine Bitsaktsis, Kari Wiedinger, Edmund Joseph GosselinMucosal pathogens are a primary source of infection that require the development of vaccines to induce a specific, protective and long lasting immune response. Despite an urgent need, development of effective mucosal immunization strategies has proven difficult. The literature was reviewed to elucidate cell specific targets that may be utilized to increase the immunogenicity of protective antigens through mucosal vaccination. … …American Journal of Immunology, Vol. 9, Issue 1 · 2 Feb 2013 · 7,026 accessesView PDFCite
Research ArticleOpen accessIn the abstractSerological Evaluation of Brucella abortus S99 Lipopolysaccharide Extracted by an Optimized MethodAli Sharifat Salmani, Seyed Davar Siadat, Mohammad Reza Fallahian et al.Problem statement: Brucellosis is a globally found infectious disease and there is no licensed vaccine against human brucellosis. The present study carried-out to evaluate the potency of our modified extracted lipopolysaccharide (LPS) of B. abortus to elicit specific anti-Brucella antibodies in animal model (Rabbit) as a part of a candidate vaccine for brucellosis. Lipopolysaccharide is one of the main virulence … …American Journal of Infectious Diseases, Vol. 5, Issue 1 · 31 Mar 2009 · 9,080 accessesView PDFCite
Review ArticleOpen accessAll words, across the recordHost Receptor Immunomodulation in Response to Shigella Surface Antigens: An Insight for Vaccine DevelopmentAshim K. Bagchi, Rushita A. Bagchi, Dipak K. Hens et al.Shigellosis, caused by Shigella is the most common cause of bacillary dysentery. The disease is associated with high morbidity and mortality rate owing to its multiple drug resistance. Hence recovery from the disease would primarily depend on the development of an effective immune-modulator for strong mucosal immune response. The role of cellular immunity may be a critical factor in protection … …American Journal of Immunology, Vol. 11, Issue 2 · 21 Jun 2015 · 6,752 accessesView PDFCite