Research ArticleOpen accessIn the keywordsInhibition of Interleukin-6 Expression by Curcumin in Rat Vascular Smooth Muscle Explants In VitroYanti, Stephanie, Yuliani et al.In atherosclerotic plaques, infectious agents from microbes may release Lipopolysaccharide (LPS) and heat shock proteins that can stimulate the production of mediators, i.e., pro-inflammatory cytokines, by vascular endothelial cells and Smooth Muscle Cells (SMCs). The elevated level of Interleukin-6 (IL-6) is strongly associated with the development of atherosclerosis. Here, we investigated whether curcumin isolated from the rhizome of Curcuma longa … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 4 · 15 Dec 2014 · 6,774 accessesView PDFCite
Research ArticleOpen accessIn the keywordsMicroarray Analysis of Human Vascular Smooth Muscle Cell Responses to Bacterial LipopolysaccharideJoe Minta James, J. Yun, Sandy Der, Shikha RanaAccumulating evidence suggest a causal role of bacterial and viral infections in atherogenesis. Bacterial lipopolysaccharide (LPS) has been shown to stimulate resting vascular smooth muscle cells (SMC) with the production of inflammatory cytokines and modulation of quiescent cells to the proliferative and synthetic phenotype. To comprehensively identify biologically important genes associated with LPS-induced SMC phenotype modulation, we compared the transcriptomes … …American Journal of Immunology, Vol. 3, Issue 2 · 31 Dec 2007 · 6,994 accessesView PDFCite
Research ArticleOpen accessIn the abstractUltrastructural Organization of the Muscular System Body of the Trematode Schistogonimus RarusIrina Yurievna ChidunchiIt is known that parasitic flatworms of the class Trematoda have a unique complex life cycle, and have morphological features of adaptation, movement, and existence in the host body. Functional peculiarities of the parasitic way of life are conditioned by the developed muscular system, due to which there is movement and attachment of the snail to various organs of the … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 16 Nov 2023 · 4,854 accessesView PDFCite
Research ArticleOpen accessIn the abstractHistomorphochemical Studies on Accessory Glands of Iraqi Blackbuck (Caprus Hircus)Waleed J. A. Al-Kelaby, Wafaa Hadi Mousa AL-Hashem, Zahraa S. M. Al Kaabi et al.Thevarious species' male accessory genital glands vary and are intimately relatedto the pelvic urethra. These glands secrete nutritional substances, buffers,and mucous to increase volume, serve as lubricants, reduce the minor acidity ofvaginal contents and make the environment more hospitable to motile sperm. Thisstudy aims to study the histological and histochemical structure of the maleaccessory sex glands in caprine Iraqi breeds. … …American Journal of Animal and Veterinary Sciences, Vol. 17, Issue 4 · 25 Nov 2022 · 5,382 accessesView PDFCite
Review ArticleOpen accessIn the abstractMicroRNA-92a: The Administrator of Certain DiseasesZhiyuan Sun, Qing Xu, Xiaoyi Tian et al.MicroRNA-92a (miR-92a) is an evolutionarily conserved noncoding small RNA that can regulate gene expression after transcription. Previous studies have found that miR-92a is overexpressed in many tumors and can regulate numerous tumor suppressor genes negatively, with relevant effects on the development of different tumors, by regulating the DUSP10/c-Jun N-terminal kinase (JNK), phosphatase and tensin homologs (PTEN)/AKT, Wnt and EP4/Notch1 signaling … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 21 May 2020 · 6,494 accessesView PDFCite
EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,281 accessesView PDFCite