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27 results for “Secondary structures”

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Research ArticleOpen accessPhrase in the titleMinimum Free Energy Based Evaluation of mRNAs Secondary Structures Constructed by 18 Clinically Significant Exonic Single Nucleotide Polymorphisms (SNPs) and Haplotypes of 5 Missense SNPs of RB1 GeneSarder Nasir Uddin, Apurba Majumder, Khandker Khaldun Islam et al.Clinically significant 18 Single Nucleotide Polymorphisms (SNPs) from exon regions of Retinoblastoma gene (RB1) were analyzed to find out the structural variations in mRNAs. Online bioinformatic tools i.e., Vienna RNA, RNAfold were used for secondary structure analysis of mRNAs. Predicted minimum Free Energy Change (MFE) was calculated for mRNAs structures. It has been observed that the average of predicted MFE … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 21 Oct 2015 · 8,556 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleImproving Protein 3D Structure Prediction Accuracy using Dense Regions Areas of Secondary Structures in the Contact MapAmer F. Al-Badarneh, Mohammad A. Khalil, Mo'taz A. Al-HamiProblem Statement: The protein folding problem is a fundamental problem in structural molecular biology. This problem describes how a protein is transformed from its primary sequence (i.e., amino acid sequence) into the three dimensional structure (3D structure) for this sequence that determines the function of the protein. The 3D structure of a protein can be represented using a square symmetrical … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 4 · 31 Dec 2008 · 7,533 accessesView PDFCite
Research ArticleOpen accessIn the keywordsBinding Studies of Natural Product Berberine with DNA G-QuadruplexNagendra K. Sharma, Pooja Lunawat, Manjusha DixitProblem statement: The ends of chromosome had highly repetitive short G and C-rich sequences of DNA. These sequences were known to form stable tetraplex type of secondary structures which help to maintain gene integratity after cell divison. Approach: Any reagent which controls the random cell division would be useful to design anticancer drugs. Therefore a many natural and synthesized molecules … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 3 · 22 Sep 2011 · 8,797 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Analysis of Proteins in Two Typical Chinese Thin-Shell WalnutsXu Meng, Tian YilingThis study compared functional properties and molecular characteristics of proteins from two thin-shelled walnut (Juglans regia L.) cultivars predominantly grown in China: Wen 185 and Lvling. Wen 185 walnut protein demonstrated significantly superior performance compared to Lvling across multiple functional parameters, including solubility, emulsifying capacity, foaming capacity, water absorption, and oil absorption. Molecular weight distribution analysis revealed that both proteins … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,481 accessesView PDFCite
Literature ReviewOpen accessIn the abstractRemineralization Potential of Bioactive Composite Resins: A Systematic ReviewLuiza Maria Schneider, Maria Ritha Veiga Colognese, Poliana Maria de Faveri Cardoso et al.To evaluate the clinical performance and potential of giomer-based materials in promoting the remineralization of dental structures through a systematic review of the literature. A comprehensive literature search was conducted using PubMed, Scopus, and Web of Science databases up to March 2024. “giomer,” “S-PRG,” “bioactive restorative materials,” “remineralization,” and “dental caries.” Inclusion criteria comprised clinical studies involving human subjects, with … …Current Research in Dentistry, Vol. 17, Issue 1 · 29 Jan 2026 · 3,135 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtein Secondary Structure Prediction using Hybrid Recurrent Neural NetworksRomana Rahman Ema, Akhi Khatun, Md. Alam Hossain et al.The most important and challenging problem in bioinformatics is protein secondary structure prediction. The molecules of all protein organisms have three-dimensional (primary, secondary, 3-D) structures which are completely recognized by the sequence of amino acids. Protein secondary structure attributes to the polypeptide backbone of the local configuration of proteins. Most generally, the second-level prediction is indicated such as: If there … …Journal of Computer Science, Vol. 18, Issue 7 · 14 Jul 2022 · 7,332 accessesView PDFCite
Review ArticleOpen accessIn the abstractProtein Sequences Features Extraction for Predicting Beta- Turns and their Types: A ReviewMurtada Khalafallah Elbashir ElfakiBeta-turns are considered to be important secondary structure types that have essential role in molecular recognition, protein folding and stability. They represent 25% of protein structures, therefore they are the most common type of non-repetitive or tight turns structures. Their prediction is considered to be an important issue in bioinformatics and molecular biology, because it provides valuable information and inputs … …Journal of Computer Science, Vol. 15, Issue 9 · 1 Oct 2019 · 7,694 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Impacts of Administrative Structure on the Functions of Local Government in Nigeria (a Study of Ikorodu Local Government)Olasunkanmi Olusogo OlagunjuThis research paper is an attempt to explicitly investigate the relationships between administrative structures and functions of Nigeria's local government. It will succinctly define the concept of local government, its history and the objectives of establishing grassroots government in Nigeria. Having adopted both primary and secondary means of data collection, this paper will therefore examine how the local government strives … …Journal of Social Sciences, Vol. 15, Issue 1 · 24 Jun 2019 · 9,768 accessesView PDFCite
Research ArticleOpen accessIn the abstractLow-Homology Protein Structural Class Prediction from Secondary Structure Based on Visibility and Horizontal Visibility NetworkZhi-Qin Zhao, Liang Luo, Xiao-Yan LiuIn this study, based on the predicted secondary structures of proteins, we propose a new approach to predict protein structural classes (α,β,α/β,α+β) for three widely used low-homology data sets. Fist, we obtain two time siries from the chaos game representation of each predicted secondary structure; second, based on two time series, we construct visibility and horizontal visibility network, respectively and … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 1 · 12 Mar 2018 · 9,668 accessesView PDFCite
Research ArticleOpen accessIn the abstractAdsorption Behavior of Bone Morphogenetic Protein-2 on a Graphite Substrate for Biomedical ApplicationsIzabele Marquetti, Salil DesaiThe interaction of proteins with biomaterials plays an important role for several biomedical applications including implants and tissue engineering. Although different experimental approaches have been explored, the investigation of the molecular models for protein-substrate interaction is warranted to control of cellular functions. In this study, Molecular Dynamics (MD) simulations were used to study the adsorption behavior of Bone Morphogenetic Protein-2 … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 2 · 19 Jun 2018 · 8,705 accessesView PDFCite