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19 articles for “Platelets”
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Research ArticleOpen accessEvery word in the titlePlatelets, Coagulation and Cancer: Multifaceted InteractionsT. Burnouf, H. A. GoubranApproach: Literature review of the multifaceted interactions between platelets, coagulation and cancer. Results: Over the years, the links existing between cancer development, progression and occurrence of metastasis on one side and coagulation on the other have become obvious. Tumors seems to activate platelets whereas, platelets, on the other hand, through their capacity to activate and release soluble factors and microparticles, … …Current Research in Medicine, Vol. 3, Issue 2 · 30 Jul 2012 · 7,613 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePatient and Mouse Antibodies against Dengue Virus Nonstructural Protein 1 Cross-React with Platelets and Cause Their Dysfunction or DepletionChiou-Feng Lin, Huan-Yao Lei, Ching-Chuan Liu et al.Thrombocytopenia is a clinical manifestation in dengue virus (DV) infection, yet its pathogenic mechanisms are unresolved. We previously showed that dengue patient sera contained antibodies cross-reactive with platelets. In this study, we demonstrated that the anti-platelet activity of dengue patient sera was due to the antibodies against DV nonstructural protein 1 (NS1). Studies using DV-infected or recombinant NS1-immunized mouse sera … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,321 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAnti-Platelet and Anti-Endothelial Cell Autoantibodies in Vietnamese Infants and Children with Dengue Hemorrhagic FeverNguyen Thanh Hung, Nguyen Trong Lan, Yee-Shin Lin et al.Dengue hemorrhagic fever (DHF) is a serious public health problem. Increased vascular permeability and thrombocytopenia are the hallmarks of DHF. The mechanisms involved in DHF/Dengue shock syndrome (DSS) pathogenesis is not fully understood. This study gives evidence of the presence of antibodies which cross-reacted with platelets, and endothelial cells in the sera of Vietnamese infants and children with DHF/DSS. The … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,369 accessesView PDFCite
Research ArticleOpen accessIn the keywordsRelease of Endogenous Chondroitin Sulfate and Heparin as Consequence of Dysregulated Proteolysis in COVID-19Marco RuggieroInfection by severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), the pathogen responsible for COVID-19, is associated with immune-mediated responses that lead to dysregulated activation of proteolytic enzymes; these contribute to damage to the endothelium, thrombosis, hypercoagulability and other hematologic complications that include thrombotic thrombocytopenia, a complication of severe COVID-19 as well as a potentially fatal adverse effect of COVID-19 vaccination. … …American Journal of Immunology, Vol. 17, Issue 1 · 29 Dec 2021 · 7,688 accessesView PDFCite
Review ArticleOpen accessIn the abstractOverview of Atherosclerotic Plaque: From Formation to ComplicationAnastasia Vladimirovna Poznyak, Varvara Alexandrovna Orekhova, Vasily Nikolaevich Sukhorukov et al.Atherosclerosis is a serious worldwide health problem. The pathogenesis of this disease is complex and includes a multilevel interaction of such processes as inflammation, endothelial dysfunction, mitochondrial dysfunction, and multiple modifications of lipid particles. With the increase in life expectancy, mankind is more and more often faced with the unpleasant consequences of atherosclerosis. Atherosclerosis is a precursor to serious health … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 6 Mar 2024 · 5,393 accessesView PDFCite
Research ArticleOpen accessIn the abstractHematological Biomarkers in Nellore Cows of Different Ages from the Bolivian TropicsAtsuko Ikeda, Pablo Roberto MariniThe objective of the work was to evaluate if the multiparous adult cows presented any difference in the values of hematological biomarkers compared to young primiparous Nellore cows from the Bolivian tropics. During the month of February 2021, a study was carried out with 14 multiparous adult cows and 13 young prim parous cows. The cows used were: Adult cows … …American Journal of Agricultural and Biological Sciences, Vol. 17, Issue 1 · 4 Feb 2022 · 6,898 accessesView PDFCite
Research ArticleOpen accessIn the abstractMechanically Stimulated Osteoblast Cells GrowthRaffaella Aversa, Antonio Apicella, Francesco Tamburrino, Florian Ion Tiberiu PetrescuThe bones need to be built and then permanently restored to keep them functioning properly. Considering the multiple bone functions, their vitality is essential both to maintain the body and move it and to maintain its health and vigor. When most bones begin to age and have no vital function, the man also begins to age, lose water, minerals, electrolytes, … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 2 · 19 Jun 2018 · 7,882 accessesView PDFCite
Review ArticleOpen accessIn the abstractA Stochastic Approach to Blood Supply, Demand and Screening in Central Blood Banks - A ReviewShaul K. Bar-LevOne of the major issues in securing blood supply to patients worldwide is to provide blood of the best achievable quality, in the needed quantities. Central Blood Services (CBS’s) worldwide are daily faced with the problem how to satisfy demands for blood from various hospitals. These hospitals, in their turn, are faced with the problem how to satisfy demands for … …Current Research in Biostatistics, Vol. 7, Issue 1 · 26 Oct 2017 · 8,072 accessesView PDFCite
EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,281 accessesView PDFCite
EditorialOpen accessIn the abstractNeutrophil Extracellular Traps as Therapeutic Targets for Inflammatory DiseaseRory R. KoenenNeutrophilic granulocytes, or neutrophils are the most abundant circulating white blood cell and constitute a first line of defense against pathogens. They are characterized by a large polymorphic lobular nucleus and the presence of many secretory granules in their cytoplasm. Neutrophils are essential for a functional host defense, as is evidenced by the occurrence of severe infections in individuals with … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 25 Feb 2015 · 8,737 accessesView PDFCite