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6 results for “Plaque Formation”
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Research ArticleOpen accessPhrase in the titleVitamin D Supplements Tone Down the Progression of Atheromatous Plaque Formation in a Dose-Dependent MannerAhmed Farouk, Khalid M. Mohany, Magdy Algowhary et al.Hypovitaminosis D has a negative impact on the cardiovascular system. We performed the current study to investigate the expression of Vitamin D Receptor (VDR) in atherosclerotic human male aortas and to examine the effect of different doses of Vit. D supplementation on VDR expression in the aortas of male rats fed a High-Fat Diet (HFD). Human participants included 50 atherosclerotic … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 3 · 5 Oct 2021 · 6,724 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleOverview of Atherosclerotic Plaque: From Formation to ComplicationAnastasia Vladimirovna Poznyak, Varvara Alexandrovna Orekhova, Vasily Nikolaevich Sukhorukov et al.Atherosclerosis is a serious worldwide health problem. The pathogenesis of this disease is complex and includes a multilevel interaction of such processes as inflammation, endothelial dysfunction, mitochondrial dysfunction, and multiple modifications of lipid particles. With the increase in life expectancy, mankind is more and more often faced with the unpleasant consequences of atherosclerosis. Atherosclerosis is a precursor to serious health … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 6 Mar 2024 · 5,393 accessesView PDFCite
Review ArticleOpen accessIn the keywordsRole of HDL in Atherogenesis: Cholesterol and AtheroprotectionAnastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Victor Yurievich Glanz et al.Atherosclerosis is a major global health burden, responsible for a significant proportion of cardiovascular morbidity and mortality worldwide. Its high prevalence and severe clinical consequences have made it a subject of extensive research. Despite considerable advances, the complexity of its pathogenesis continues to hinder the development of effective preventive strategies and therapeutic interventions. Current evidence implicates chronic inflammation, dysregulated lipid … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 3 Apr 2026 · 1,476 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Effect of Main Heat Shock Proteins on AtherosclerosisAnastasia Vladimirovna Poznyak, Alexey V. Churov et al.Atherosclerosis is a multifaceted disease characterized by complex pathogenesis involving diverse mechanisms. In recent years, the autoimmune nature of atherosclerosis has gained significant attention, emphasizing the indispensable role of the immune system in its initiation and progression. Heat Shock Proteins (HSPs) are vital for cellular functionality, facilitating cellular adaptation to environmental changes and survival under adverse conditions. Notably, various HSP … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 3 Oct 2024 · 4,354 accessesView PDFCite
Review ArticleOpen accessIn the abstractSubfractions of Low-Density-Lipoprotein: Which is the Most Atherogenic?Anastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Mikhail Аleksandrovich Popov et al.Atherosclerosis is a widespread disease of the arteries, which manifests itself in the narrowing of the lumen of the vessel due to the formation of plaque on its walls. Despite an impressive history of study, atherosclerosis still leaves room for researchers. This is realized due to the complexity of pathogenesis, in which important roles are assigned to a variety of … …OnLine Journal of Biological Sciences, Vol. 23, Issue 4 · 3 Sep 2023 · 4,697 accessesView PDFCite
Review ArticleOpen accessIn the abstractBioactive Functional Foods for Cardiovascular DiseasesKiren Mustafa, Iqra Ajmal, Tahira Naz et al.Cardiovascular Disease (CVD) is a chronic pathological disorder regarded as a serious health concern round the globe. It is a multifactorial disease, with a range of various causative agents, among that dietary factor is considered the most important and may to a large degree determine CVD risk. Unfortunately, it has been less widely investigated. This review outlines the general aspects … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 17 Aug 2020 · 7,831 accessesView PDFCite