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139 articles for “NAD+”
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Research ArticleOpen accessEvery word in the titleThe Burr X Nadarajah Haghighi Distribution: Statistical Properties and Application to the Exceedances of Flood Peaks DataHisham A.H. Elsayed, Haitham M. YousofIn this study, new version from the Nadarajah Haghighi model is proposed. The introduced model has a failure rate function that may change in different directions. Statistical properties of the new density function are derived along with the analysis of variance, Skewness and Kurtosis. Parameter estimates are obtained by the method of maximum likelihood. Illustration of real data set was … …Journal of Mathematics and Statistics, Vol. 15, Issue 1 · 14 Jul 2019 · 7,132 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSynthetic Pyrethroid Resistance in Field Strains of Helicoverpa armigera (Hubner) (Lepidoptera: Noctuidae) in Tamil Nadu, South IndiaP. Duraimurugan, A. RegupathyResistance to synthetic pyrethroids was diagnosed in the field population of American bollworm, Helicoverpa armigera (Hubner) from Coimbatore, Tamil Nadu, South India during 2003-2004 cropping seasons. A Discriminating Dose (DD) bioassay technique was used to monitor fortnightly changes in resistance at Coimbatore where number of crops served as host plants for this pest. The resistance level of various synthetic pyrethroids … …American Journal of Applied Sciences, Vol. 2, Issue 7 · 31 Jul 2005 · 6,856 accessesView PDFCite
EditorialOpen accessEvery word in the titleEditorial Commentary: Challenge of Non–AIDS-Defining Cancers (NADCs), Focusing on Trans Activation Response Element (TAR) RNA Embedding ExosomesLechuang Chen, Ge JinGlobally, 37.9 million people were living with HIV at the end of 2018 (Organization, 2018). Cancer is a major cause of mortality and morbidity in AIDS patients and chronically HIV-infected people. With the aid of combination Antiretroviral Therapy (ART), people living with HIV (PLWH) have a longer life span. However, because the virus is not completely eradicated, PLWH under antiretroviral … …American Journal of Immunology, Vol. 15, Issue 1 · 28 Nov 2019 · 6,657 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEnhanced Fatty Acid Production in Escherichia coli by Over-Expression of NADPH Generating EnzymesYuanda Song, Yong Q. Chen, Haiqin Chen et al.NADPH is an essential factor for Fatty Acid (FA) biosynthesis. The effect of NADPH generating enzymes [NADP+-dependent malic enzyme (NADP-ME), NADP+-dependent isocitrate dehydrogenase (NADP-IDH), Glucose 6-Phosphate Dehydrogenase (GPD) and 6-Phosphogluconate Dehydrogenase (PGD)] on FA biosynthesis was investigated in an engineered Escherichia coli BL21 △fadE/pTE. Among NADPH-generating enzymes, GPD and ICD increased total FA production by 60 and 16% respectively. Especially … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 23 Oct 2017 · 8,578 accessesView PDFCite
Literature ReviewOpen accessIn the keywordsPotential Therapies for Mitochondrial Diseases Caused by mtDNA MutationsAnastasia V. Poznyak, Nikolay A. Orekhov, Dmitry Felixovich Beloyartsev et al.Mitochondrial diseases, caused by mutations in mitochondrial DNA (mtDNA), present significant genetic and clinical complexities that challenge accurate diagnosis and treatment. This review examines the critical molecular mechanisms underlying these disorders, particularly the role of heteroplasmy, where mixtures of mutated and normal mtDNA influence disease severity, and the nuclear-mitochondrial DNA interactions that compound diagnostic and therapeutic challenges. The threshold effect, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,735 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIs RNA Binding in the Rossmann Fold Essential for GAPDH Intranuclear Functions?Natalia Krynetskaia, Manali Phadke, Evgeny KrynetskiyIn addition to its prominent enzymatic activity, GAPDH is an enigmatic component of multiple unrelated biochemical entities. In this study, we explored a series of mutated GAPDH and fusion EGFP-GAPDH polypeptides and compared nuclear accumulation, intranuclear mobility and RNA binding properties of the wild type and variant GAPDH proteins. Our results revealed that RNA binding to T99I-mutated GAPDH with non-functional … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 2 · 14 Jun 2016 · 7,657 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEnhancing Dam Safety and Management: Long Short-Term Memory Based Predictive Models for Accurate Alert ForecastingNisha C. M, N. ThangarasuDam management and early alert systems are critical for effective water resource management. Accurate prediction of dam alert signals facilitates proactive decision-making, thereby aiding in the effective management and reduction of potential risks linked to dam operations. Within this research, Long Short-Term Memory (LSTM) networks are utilized to forecast dam alert signals issued from the dam by leveraging daily parameters, … …Journal of Computer Science, Vol. 22, Issue 1 · 6 Feb 2026 · 1,626 accessesView PDFCite
Research ArticleOpen accessIn the keywordsBoosted Regression Estimates of Spatial Data: Pointwise InferenceMarco Di Marzio, Charles C. TaylorIn this study simple nonparametric techniques have been adopted to estimate the trend surface of the Swiss rainfall data. In particular we employed the Nadaraya-Watson smoother and in addition, an adapted-by boosting-version of it. Additionally, we have explored the use of the Nadaraya-Watson estimator for the construction of pointwise confidence intervals. Overall, boosting does seem to improve the estimate as … …Journal of Mathematics and Statistics, Vol. 1, Issue 4 · 31 Dec 2005 · 6,349 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAntioxidant and Photosynthetic Responses in Plants Under Boron Toxicity: A ReviewLucia Guidi, Alberto Pardossi, Elena Degl’Innocenti, Marco LandiBoron (B) is a micronutrient that has long been known essential not only for plants and animals. Otherwise, in crop plants the range of B concentration from essentiality to toxicity appears extremely narrow. Although B deficiency has been well investigated, during recent years many researchers have also investigated boron toxicity effects, making progress in the comprehension of boron transport within … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 3 · 5 Jul 2012 · 12,762 accessesView PDFCite
Research ArticleOpen accessIn the keywordstNOX (ENOX2) Target for Chemosensitization-Low-Dose Responses in the Hormetic Concentration RangeD. James Morre, Sara Dick, Elena Bosneaga et al.An emerging concept of cancer chemotherapy is that of chemosensitization. Most often applied to the treatment of drug-resistance cancers, chemosensitization has utility when such cancers are rendered drug sensitive through treatment with the sensitizing agent. A particularly striking example of chemosensitization is that encountered with the synthetic isoflavene phenoxodiol where patients with taxane- and/or platinum-resistant ovarian carcinoma once again become … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,568 accessesView PDFCite