6 articles for “Myeloma”

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Research ArticleOpen accessEvery word in the titleUse of an Extremely Biodiverse Probiotic and a Supplement Based on Microbial Chondroitin Sulfate is Associated with a Significant Decrease of Serum Free Kappa Light Chains as well as a Trend Toward Normalization of Kappa/Lambda Ratio and of Plasma Cell Bone Marrow Infiltration in a Case of Multiple MyelomaNicola Antonucci, Stefania Pacini, Marco RuggieroWe describe the case of a 71-year-old woman with multiple myeloma associated with severe chronic renal insufficiency who, since October 2018, assumed a novel, extremely biodiverse, probiotic and a supplement based on microbial chondroitin sulfate, vitamin D3 and ultrapure phosphatidylcholine; such a nutritional regimen was associated with a dramatic decrease of serum free Kappa light chains (from 2,190 to a … …American Journal of Immunology, Vol. 15, Issue 1 · 18 Jun 2019 · 27,919 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsRevealed «Oncologic Markers» in the Sea Star Antibody Response to Horse-Radish PeroxydaseMichel Leclerc, Patricia OttenAt least two genes found in the genome of Asterias rubens after immunizations to the antigen Horse-Radish Peroxydase (HRP), could play the role of oncologic markers: The first one (Igkappa chain V-V region T 1 S 107 B precursor) reveals myeloma; The second (B cell CLL/Lymphoma 9-like) as the first one has a kinship to the IgKappa gene subfamily. …American Journal of Immunology, Vol. 9, Issue 4 · 16 Nov 2013 · 6,807 accessesView PDF Cite

EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,865 accessesView PDF Cite

Research ArticleOpen accessIn the abstractPRODUCTION AND CHARACTERIZATION OF MONOCLONAL AND POLYCLONAL ANTIBODY AGAINST RECOMBINANT OUTER MEMBRANE PROTEINMahdi Fasihi-Ramandi, Amir Nedjad-Moghaddam, Fatemeh Arabsalmany et al.There are many studies related to immunological and molecular methods for diagnosis of Vibrio cholera (V. cholerae). However, most assays dependent on enrichment of culture of bacteria, which need more time and involves the use of costly equipment and reagents. In this study Balb/c mice were immunized with recombinant Outer Membrane Protein (rOMPw) of vibrio cholerae and splenocytes of hyper … …American Journal of Immunology, Vol. 10, Issue 1 · 26 Apr 2014 · 7,444 accessesView PDF Cite

Research ArticleOpen accessIn the abstractPlant Pectin: A Potential Source for Cancer SuppressionSuryakant K. Niture, Lubna RefaiPectin is a branched polysaccharide present widely in a variety of fruits. It has been of high interest to cancer biologists due to its involvement in metal/carcinogen detoxification and its anti-carcinogenic properties. In particular, Citrus Pectin (CP) and Modified Citrus Pectin (MCP) have been shown to have a significant inhibitory role in cancer cell metastasis, invasion, angiogenesis and survival. The … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 1 · 18 Apr 2013 · 15,532 accessesView PDF Cite

Research ArticleOpen accessIn the abstractChemical Composition of Propolis from Different Regions in Java and their Cytotoxic ActivitySyamsudin, Sudjaswadi Wiryowidagdo, Partomuan Simanjuntak, Wan Lelly HeffenProblem statement: Propolis samples from tropical zones, such as Java (Indonesia) with its vast biodiversity, have become a subject of increasing scientific and economic attention. The association of the chemical composition of propolis from different geographic regions with cytotoxic activities lead to the identification of active principles, a fundamental tool to achieve standardization of this bee product. Approach: The purpose … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 4 · 31 Dec 2009 · 8,273 accessesView PDF Cite