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5 results for “Mucor circinelloides”
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Research ArticleOpen accessPhrase in the titleExpression and Induction Optimization of Mucor Circinelloides Lipase in Escherichia ColiYueping Yang, Yao Zhang et al.Microbial lipases serve as versatile biocatalysts for modifying lipid substrates, enabling diverse biotechnological applications spanning food technology, renewable energy production, and pharmaceutical sectors. Genomic analysis of Mucor circinelloides WJ11 revealed multiple lipase-encoding genes, with WJ_23 successfully cloned and heterologously expressed in Escherichia coli. Since the lipase expression was mainly concentrated in the cell pellets, appropriate induction strategies had been investigated … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 13 Jun 2025 · 5,982 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleEffect of Adding Cellulose on Lipid Accumulation in Cellobiohydrolase and Delta-6 Desaturase Engineered Mucor circinelloides StrainsYao Zhang, Yanxia Wang et al.Despite microbial production of multifunctional gamma-linolenic acid (GLA) being an important and promising way, the high cost is still a major factor limiting industrial applications. Previously, we proposed a novel approach to promote the production of GLA from cellulose, a widely available and cheapest resource, by overexpression of the cellobiohydrolase (CBH2) and delta-6 desaturase (D6) in Mucor circinelloides. In the … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 3 · 13 Oct 2023 · 4,731 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleThe Effect of Soybean Oil on Lipid Metabolism in Mucor circinelloides WJ11 by Metabolomic AnalysisCaili Sun, Aabid Manzoor Shah, Junhuan Yang et al.Oleaginous fungus Mucor circinelloides utilizes different carbon sources associated with sustainable production of lipids, using soybean oil as carbon source, the fungus accumulated more intracellular lipids. Nonetheless, the metabolic changes in M. circinelloides upon vegetable oil as main carbon source have not been yet reported. Therefore, this study was conducted to investigate the metabolomics of M. circinelloides WJ11 cultivated in … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 2 · 9 Apr 2021 · 7,199 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleImproved SDA Production in High Lipid Accumulating Strain of Mucor circinelloides WJ11 by Genetic ModificationJunhuan Yang, Md. Ahsanul Kabir Khan, Sergio López-García et al.Stearidonic Acid (SDA; 18:4, n-3) is a ω-3 polyunsaturated fatty acid which is nutritionally important and has pharmaceutical applications. Hence, scientists are trying to construct SDA producing oleaginous microorganisms by genetic modification. Two enzymes, Delta-6 Desaturase (D6D) and ω-3 desaturase catalyze the reactions to produce SDA from Linoleic Acid (LA; 18:2, n-6). But the key enzyme, ω-3 desaturase converts LA … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 1 · 23 Mar 2020 · 8,240 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPreparation of Rose Vinegar Rich in Gamma-Linolenic Acid and Analysis of its Nutritional Composition and Antioxidant ActivityYao Zhang, Qing Liu et al.Despite the rapid development of various types of fruit vinegar or nutrient-fortified vinegar, the weakened functions or high cost is still the main limiting factor for healthy vinegar. In the present study, a new type of rose vinegar was obtained from raw grain supplemented with natural extract of roses through the cooperative fermentation of multiple microorganisms by adding Mucor circinelloides … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 3 · 8 Aug 2023 · 6,388 accessesView PDFCite